{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T16:13:13Z","timestamp":1780416793296,"version":"3.54.1"},"reference-count":55,"publisher":"American Chemical Society (ACS)","issue":"20","license":[{"start":{"date-parts":[[2021,10,7]],"date-time":"2021-10-07T00:00:00Z","timestamp":1633564800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,10,7]],"date-time":"2021-10-07T00:00:00Z","timestamp":1633564800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,10,7]],"date-time":"2021-10-07T00:00:00Z","timestamp":1633564800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["R01ES031657"],"award-info":[{"award-number":["R01ES031657"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81903281"],"award-info":[{"award-number":["81903281"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ. Sci. Technol."],"published-print":{"date-parts":[[2021,10,19]]},"DOI":"10.1021\/acs.est.1c04008","type":"journal-article","created":{"date-parts":[[2021,10,7]],"date-time":"2021-10-07T14:56:03Z","timestamp":1633618563000},"page":"14087-14094","source":"Crossref","is-referenced-by-count":39,"title":["Relationship between Blood Trihalomethane Concentrations and Serum Thyroid Function Measures in U.S. Adults"],"prefix":"10.1021","volume":"55","author":[{"given":"Yang","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, United States"},{"name":"Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng-Fei","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. I. M.","family":"Korevaar","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Academic Center for Thyroid Diseases, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicente","family":"Mustieles","sequence":"additional","affiliation":[{"name":"Center for Biomedical Research (CIBM), University of Granada, 18016 Granada, Spain"},{"name":"Instituto de Investigaci\u00f3n Biosanitaria Ibs GRANADA, 18012 Granada, Spain"},{"name":"Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), 28029 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, United States"},{"name":"Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiong-Fei","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Ministry of Education Key Laboratory of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China"},{"name":"Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37203, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4324-2408","authenticated-orcid":true,"given":"Yi-Xin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3884-1492","authenticated-orcid":true,"given":"Carmen","family":"Messerlian","sequence":"additional","affiliation":[{"name":"Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, United States"},{"name":"Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2021,10,7]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2008.01733.x"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2012.01.006"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2012.01.004"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2012.01.007"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1210\/er.2018-00163"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx050"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.1361"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.0800247"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1080\/03601238209372315"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/es402646c"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1177\/019262339802600501"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1080\/019262301317052530"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/89.12.848"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.8b01802"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.824657"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1080\/00039890409603437"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1289\/ehp7195"},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/B978-0-444-52272-6.00103-3","volume-title":"Encyclopedia of Environmental Health","volume":"3","author":"Blount B.","year":"2011"},{"key":"ref19\/cit19","unstructured":"NCHS About the National\nHealth and Nutrition Examination Survey. https:\/\/www.cdc.gov\/nchs\/nhanes\/about_nhanes.htm (accessed Sept 15, 2020)."},{"key":"ref20\/cit20","unstructured":"NCHS National Health\nand Nutrition Examination Survey. https:\/\/www.cdc.gov\/nchs\/nhanes\/index.htm?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fnchs%2Fnhanes.htm (accessed Nov 30, 2021)."},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-0431"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2015.03.050"},{"key":"ref23\/cit23","unstructured":"NCHS Laboratory Procedure Manual. Trihalomethanes\/MTBE\/Nitromethane. https:\/\/wwwn.cdc.gov\/nchs\/data\/nhanes\/2011-2012\/labmethods\/VOCMWB_G_MET.pdf (accessed April 30, 2021)."},{"key":"ref24\/cit24","unstructured":"NCHS 2007-2008 Data\nDocumentation, Codebook, and Frequencies. Volatile\nOrganic Compounds-Trihalomethanes\/MTBE\/Nitromethane-Blood (VOCMWB_E). https:\/\/wwwn.cdc.gov\/Nchs\/Nhanes\/2007-2008\/VOCMWB_E.htm (accessed\nApril 30, 2021)."},{"key":"ref25\/cit25","unstructured":"NCHS 2007-2008 Data\nDocumentation, Codebook, and Frequencies for\nThyroid Profile. https:\/\/wwwn.cdc.gov\/Nchs\/Nhanes\/2007-2008\/THYROD_E.htm (accessed April 30, 2021)."},{"key":"ref26\/cit26","unstructured":"NCHS NHANES 2007-2008\nLaboratory Methods. https:\/\/wwwn.cdc.gov\/nchs\/data\/nhanes\/2007-2008\/labmethods\/cot_e_met.pdf (accessed April 30, 2021)."},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.1409589"},{"key":"ref28\/cit28","unstructured":"NHANES MEC Laboratory Procedures Manual. https:\/\/wwwn.cdc.gov\/nchs\/data\/nhanes\/2013-2014\/manuals\/2013_mec_laboratory_procedures_manual.pdf (accessed April 30, 2021)."},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.6809"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1996.03530400021033"},{"key":"ref31\/cit31","unstructured":"CDC Fourth National Report on Human Exposure\nto Environmental Chemicals. http:\/\/www.cdc.gov\/exposurereport\/pdf\/fourthreport.pdf (accessed\nApril 30, 2021)."},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.1409234"},{"key":"ref33\/cit33","unstructured":"NCHS Laboratory Procedure Manual. Thyroid Peroxidase Antibodies. https:\/\/wwwn.cdc.gov\/nchs\/data\/nhanes\/2007-2008\/labmethods\/thyrod_e_met_thyroid_peroxidase_antibodies.pdf (accessed April 30, 2021)."},{"key":"ref34\/cit34","unstructured":"NCHS Laboratory\nProcedure Manual. Thyroglobulin Antibodies. https:\/\/wwwn.cdc.gov\/nchs\/data\/nhanes\/2007-2008\/labmethods\/thyrod_e_met_thyroglobulin_antibodies.pdf (accessed April 30, 2021)."},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.1205239"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2010.0077"},{"key":"ref37\/cit37","unstructured":"NCHS Weighting in NHANES. https:\/\/wwwn.cdc.gov\/nchs\/nhanes\/tutorials\/module3.aspx (accessed April 30, 2021)."},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2007.0266"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2016.174"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1210\/er.2009-0041"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2014-3586"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.168.20.2219"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.115.020789"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1161\/circresaha.117.311603"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-16564-2"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2008.08.008"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.2215\/cjn.12081111"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2019.03.009"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.7931171"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.0900677"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/s0304-3894(00)00184-9"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/0160-5402(87)90070-2"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.jes.2017.04.021"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijheh.2017.01.005"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.87.3.8165"}],"container-title":["Environmental Science & Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.1c04008","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T05:01:44Z","timestamp":1682658104000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.est.1c04008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,7]]},"references-count":55,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2021,10,19]]}},"alternative-id":["10.1021\/acs.est.1c04008"],"URL":"https:\/\/doi.org\/10.1021\/acs.est.1c04008","relation":{},"ISSN":["0013-936X","1520-5851"],"issn-type":[{"value":"0013-936X","type":"print"},{"value":"1520-5851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,7]]}}}