{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T23:20:43Z","timestamp":1790896843438,"version":"4.1.0"},"reference-count":72,"publisher":"American Chemical Society (ACS)","issue":"21","license":[{"start":{"date-parts":[[2022,8,2]],"date-time":"2022-08-02T00:00:00Z","timestamp":1659398400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004052","name":"King Abdullah University of Science and Technology","doi-asserted-by":"publisher","award":["BAS\/1\/1033-01-01"],"award-info":[{"award-number":["BAS\/1\/1033-01-01"]}],"id":[{"id":"10.13039\/501100004052","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ. Sci. Technol."],"published-print":{"date-parts":[[2022,11,1]]},"DOI":"10.1021\/acs.est.2c01834","type":"journal-article","created":{"date-parts":[[2022,8,2]],"date-time":"2022-08-02T19:58:45Z","timestamp":1659470325000},"page":"15007-15018","source":"Crossref","is-referenced-by-count":74,"title":["Investigation of Antibiotic Resistome in Hospital Wastewater during the COVID-19 Pandemic: Is the Initial Phase of the Pandemic Contributing to Antimicrobial Resistance?"],"prefix":"10.1021","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9488-8789","authenticated-orcid":true,"given":"Changzhi","family":"Wang","sequence":"first","affiliation":[{"name":"Bioengineering Program, Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Kingdom of Saudi Arabia"},{"name":"Water Desalination and Reuse Center, Division of Biological and Environmental Science and Engineering, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Mantilla-Calderon","sequence":"additional","affiliation":[{"name":"Water Desalination and Reuse Center, Division of Biological and Environmental Science and Engineering, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanghui","family":"Xiong","sequence":"additional","affiliation":[{"name":"Environmental Science and Engineering, Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Kingdom of Saudi Arabia"},{"name":"Water Desalination and Reuse Center, Division of Biological and Environmental Science and Engineering, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohsen","family":"Alkahtani","sequence":"additional","affiliation":[{"name":"Environmental Health Laboratory, Ministry of Health, P.O. Box 34496, Jeddah 21468, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasir M.","family":"Bashawri","sequence":"additional","affiliation":[{"name":"General Directorate of Environment Health, Ministry of Health, P.O. Box 2903, Riyadh 11461, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamed","family":"Al Qarni","sequence":"additional","affiliation":[{"name":"General Directorate of Environment Health, Ministry of Health, P.O. Box 2903, Riyadh 11461, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4474-6600","authenticated-orcid":true,"given":"Pei-Ying","family":"Hong","sequence":"additional","affiliation":[{"name":"Bioengineering Program, Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Kingdom of Saudi Arabia"},{"name":"Environmental Science and Engineering, Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Kingdom of Saudi Arabia"},{"name":"Water Desalination and Reuse Center, Division of Biological and Environmental Science and Engineering, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,8,2]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)02724-0"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1093\/jacamr\/dlaa049"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1093\/jacamr\/dlaa051"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa524"},{"key":"ref5\/cit5","unstructured":"Organization,\nM. o. H.\n                      Saudi MoH Protocol for Patients\nSuspected of\/Confirmed with COVID-19\n                      ; Ministry\nof Health: 2020."},{"key":"ref6\/cit6","unstructured":"Srinivasan, A. In\n                      The Intersection of Antibiotic Resistance (AR), Antibiotic Use (AU), and COVID-19\n                      ; 2020."},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2021.09.008"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2020.11.010"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics10020132"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics10070778"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)32798-9"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-819722-6.00015-8"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.3390\/w10030244"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2021.07.004"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6948e1"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2021.110748"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jece.2022.107478"},{"key":"ref18\/cit18","unstructured":"Andrews, S.\n                      FastQC: a quality control tool for high throughput sequence data\n                      ; 2017."},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu170"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1923"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz935."},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1038\/nature14486"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.65088"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-020-00861-6"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2014.226"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btv033"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-06393-w"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-10-421"},{"key":"ref29\/cit29","unstructured":"Wilkins, D.\n                      gggenes: draw gene arrow maps in \u2018ggplot2\u2019\n                      , R package version 0.4.0; 2019."},{"key":"ref30\/cit30","unstructured":"Team, R. C.\n                      R: A language\nand environment for statistical computing\n                      ; 2013."},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.1319"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1101\/gr.186072.114"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2017.126"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btz848"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.3390\/w12123477"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2017.1344235"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2007.01861.x"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.sjbs.2014.08.002"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00117-13"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1021\/bi901690r"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7600898"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.3389\/fenvs.2022.845448"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1177\/1753466620951053"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2020.105949"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.5582\/ddt.2020.01012"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(21)00310-6"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00461-X"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2020.05.085"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2020.09.055"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2020.381"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2020.12.018"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2014.02.040"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.jenvman.2018.10.051"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.03760-12"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.67.4.1494-1502.2001"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00665-07"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1093\/jacamr\/dlab092"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1086\/338786"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01749-16"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkl178"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.43.3.573"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-03988-0"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.3201\/eid1202.050570"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0064097"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)33296-8"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2021.09.008"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofab185"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics10070841"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2022.02.014"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkac028"},{"key":"ref71\/cit71","unstructured":"GLASS Report: Early Implementation 2020\n                      ; World Health Organization: 2020."},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1126\/science.aba3432"}],"container-title":["Environmental Science &amp; Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.2c01834","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.2c01834","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T02:54:27Z","timestamp":1682477667000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.est.2c01834"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,2]]},"references-count":72,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2022,11,1]]}},"alternative-id":["10.1021\/acs.est.2c01834"],"URL":"https:\/\/doi.org\/10.1021\/acs.est.2c01834","relation":{"is-basis-for":[{"id-type":"doi","id":"10.52843\/cassyni.49gbpn","asserted-by":"object"}]},"ISSN":["0013-936X","1520-5851"],"issn-type":[{"value":"0013-936X","type":"print"},{"value":"1520-5851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,2]]}}}