{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T19:13:02Z","timestamp":1792005182122,"version":"4.4.0"},"reference-count":65,"publisher":"American Chemical Society (ACS)","issue":"30","license":[{"start":{"date-parts":[[2023,7,19]],"date-time":"2023-07-19T00:00:00Z","timestamp":1689724800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000139","name":"U.S. Environmental Protection Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000139","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000203","name":"U.S. Geological Survey","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000203","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ. Sci. Technol."],"published-print":{"date-parts":[[2023,8,1]]},"DOI":"10.1021\/acs.est.3c01040","type":"journal-article","created":{"date-parts":[[2023,7,19]],"date-time":"2023-07-19T12:48:58Z","timestamp":1689770938000},"page":"10940-10950","source":"Crossref","is-referenced-by-count":127,"title":["Tire-Derived Transformation Product 6PPD-Quinone Induces Mortality and Transcriptionally Disrupts Vascular Permeability Pathways in Developing Coho Salmon"],"prefix":"10.1021","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6660-9976","authenticated-orcid":true,"given":"Justin B.","family":"Greer","sequence":"first","affiliation":[{"name":"U.S. Geological Survey, Western Fisheries Research Center, Seattle, Washington 98115, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8299-7198","authenticated-orcid":true,"given":"Ellie M.","family":"Dalsky","sequence":"additional","affiliation":[{"name":"U.S. Geological Survey, Western Fisheries Research Center, Seattle, Washington 98115, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9202-0612","authenticated-orcid":true,"given":"Rachael F.","family":"Lane","sequence":"additional","affiliation":[{"name":"U.S. Geological Survey, Kansas Water Science Center, Lawrence, Kansas 66049, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John D.","family":"Hansen","sequence":"additional","affiliation":[{"name":"U.S. Geological Survey, Western Fisheries Research Center, Seattle, Washington 98115, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,7,19]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1139\/f99-283"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1577\/1548-8446-33.10.502"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3955\/046.087.0305"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1577\/1548-8446(2007)32[426:RPFESL]2.0.CO;2"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1577\/1548-8675(1994)014<0237:HDACSO>2.3.CO;2"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0028013"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1002\/eap.1615"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1002\/ieam.219"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1126\/science.abd6951"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1080\/02652030500098177"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1007\/s00244-021-00878-4"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.1c07451"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/acs.estlett.1c00682"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2022.118122"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acs.estlett.1c00910"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.2c07652"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.1c07376"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/acs.estlett.1c00148"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.0c04114"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2022.119082"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1021\/acs.estlett.2c00821"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquatox.2019.105231"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2018.03.012"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/acs.estlett.2c00467"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1139\/cjfas-2020-0240"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/acs.estlett.2c00050"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acs.estlett.1c00453"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/etc.5487"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/acs.estlett.2c00683"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu170"},{"key":"ref31\/cit31","unstructured":"Andrews, S. FastQC: a quality control tool for high throughput sequence data. http:\/\/www.bioinformatics.babraham.ac.uk\/projects\/fastqc."},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.4197"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-014-0550-8"},{"key":"ref34\/cit34","unstructured":"Pantano, L.\n                      DEGreport: Report of DEG analysis\n                      , 2017."},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btw313"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1089\/omi.2011.0118"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.0c00872"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1577\/1548-8640(1989)051<0061:RBTUAS>2.3.CO;2"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpc.2010.09.003"},{"key":"ref40\/cit40","first-page":"87","volume":"22","author":"Braunbeck T.","year":"2005","journal-title":"ALTEX-Altern. Anim. Exp."},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquatox.2010.02.019"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquatox.2016.12.015"},{"key":"ref43\/cit43","unstructured":"Manahan, C. Assessment of potential hazards of 6PPD and alternatives. https:\/\/www.ezview.wa.gov\/Portals\/_1962\/Documents\/6ppd\/6PPD%20Alternatives%20Technical%20Memo.pdf."},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0010869"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.1c03569"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01288.2004"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1124\/pr.57.2.4"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.116.306534"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2017.06.003"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20071416"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00055.2011"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1089\/jir.2014.0188"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1172\/JCI200420702"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/S0955-0674(96)80062-7"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8020143"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2016.11.029"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-153-2-201007200-00005"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.4065\/mcp.2010.0159"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1080\/21688370.2016.1154641"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2022.02.014"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-3-37"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2020.00472"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1021\/acs.estlett.2c00431"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1021\/acs.estlett.3c00196"},{"key":"ref65\/cit65","unstructured":"Greer, J. B.\n                      Mortality, morphology, and water chemistry for 6PPD-quinone exposed coho embryos\n                      , U.S. Geological Survey data release, 2023."}],"container-title":["Environmental Science &amp; Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.3c01040","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.3c01040","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,31]],"date-time":"2023-07-31T17:29:46Z","timestamp":1690824586000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.est.3c01040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,19]]},"references-count":65,"journal-issue":{"issue":"30","published-print":{"date-parts":[[2023,8,1]]}},"alternative-id":["10.1021\/acs.est.3c01040"],"URL":"https:\/\/doi.org\/10.1021\/acs.est.3c01040","relation":{},"ISSN":["0013-936X","1520-5851"],"issn-type":[{"value":"0013-936X","type":"print"},{"value":"1520-5851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,19]]}}}