{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T22:01:46Z","timestamp":1792015306746,"version":"4.4.0"},"reference-count":66,"publisher":"American Chemical Society (ACS)","issue":"2","license":[{"start":{"date-parts":[[2023,12,29]],"date-time":"2023-12-29T00:00:00Z","timestamp":1703808000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,12,29]],"date-time":"2023-12-29T00:00:00Z","timestamp":1703808000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,12,29]],"date-time":"2023-12-29T00:00:00Z","timestamp":1703808000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2020YFC1806903"],"award-info":[{"award-number":["2020YFC1806903"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21836003"],"award-info":[{"award-number":["21836003"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22193061"],"award-info":[{"award-number":["22193061"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ. Sci. Technol."],"published-print":{"date-parts":[[2024,1,16]]},"DOI":"10.1021\/acs.est.3c07559","type":"journal-article","created":{"date-parts":[[2023,12,29]],"date-time":"2023-12-29T19:46:00Z","timestamp":1703879160000},"page":"1338-1348","source":"Crossref","is-referenced-by-count":46,"title":["D-Ring Modifications of Tetracyclines Determine Their Ability to Induce Resistance Genes in the Environment"],"prefix":"10.1021","volume":"58","author":[{"given":"Huiming","family":"Tang","sequence":"first","affiliation":[{"name":"College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058, China"},{"name":"Zhejiang Provincial Key Laboratory of Organic Pollution Process and Control, Zhejiang University, Hangzhou 310058, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6820-4593","authenticated-orcid":true,"given":"Zishu","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4700-3498","authenticated-orcid":true,"given":"Baolan","family":"Hu","sequence":"additional","affiliation":[{"name":"College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5044-277X","authenticated-orcid":true,"given":"Lizhong","family":"Zhu","sequence":"additional","affiliation":[{"name":"College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058, China"},{"name":"Zhejiang Provincial Key Laboratory of Organic Pollution Process and Control, Zhejiang University, Hangzhou 310058, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,12,29]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1007\/s10311-013-0404-8"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-009-0172-6"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2021.106620"},{"key":"ref4\/cit4","unstructured":"U.S. Food and Drug Administration\n(FDA).  Summary Report on Antimicrobials\nSold or Distributed for Use in Food-Producing Animals; FDA: Silver Spring, MD, 2014."},{"key":"ref5\/cit5","unstructured":"U.S. Food and Drug Administration\n(FDA).  Summary Report on Antimicrobials\nSold or Distributed for Use in Food-Producing Animals; FDA: Rockville, MD, 2015."},{"key":"ref6\/cit6","unstructured":"State of the World\u2019s\nAntibiotics 2015: Center for Disease Dynamics,\nEconomics Policy: Washington, DC,\nUSA, 2015."},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/es102725n"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/es1007802"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.7b03623"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/es4026358"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.7b03380"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1089\/ees.2017.0520"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/es703199g"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/es902893f"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/es901221x"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/es302657r"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2017.11.067"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-29283-8"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.0c01214"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)00216-6"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.65.2.232-260.2001"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2018.04.006"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1007\/s40121-017-0153-2"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu706"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/jm00027a023"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz935"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a025387"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1128\/aac.00625-07"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1007\/s11274-009-0160-x"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1128\/aac.06187-11"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.47.12.3675-3681.2003"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1216691110"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2015.05.017"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-019-0445-2"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-019-0496-4"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1128\/aac.01326-19"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02713-09"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1128\/jb.00389-11"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.2c06684"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.3c00159"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtho.2018.05.024"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.7b00590"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-022-01119-y"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.0c01226"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.9b04116"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1038\/s43705-022-00101-y"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-29919-9"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.00648"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics9040182"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2023.215326"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-020-6665-2"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.00056-13"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.04478-22"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2022.128889"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1038\/s41559-022-01713-2"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-019-0663-0"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2021.116926"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00780-17"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.0c00983"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1910225116"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01031-21"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2018.00057"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.00342"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1016\/j.cels.2017.10.002"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1038\/nature22308"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-020-0929-x"}],"container-title":["Environmental Science & Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.3c07559","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.3c07559","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T09:20:20Z","timestamp":1705396820000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.est.3c07559"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,29]]},"references-count":66,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,1,16]]}},"alternative-id":["10.1021\/acs.est.3c07559"],"URL":"https:\/\/doi.org\/10.1021\/acs.est.3c07559","relation":{},"ISSN":["0013-936X","1520-5851"],"issn-type":[{"value":"0013-936X","type":"print"},{"value":"1520-5851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,29]]}}}