{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T11:08:22Z","timestamp":1788865702414,"version":"build-2803163510"},"reference-count":76,"publisher":"American Chemical Society (ACS)","issue":"35","license":[{"start":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T00:00:00Z","timestamp":1724284800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T00:00:00Z","timestamp":1724284800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T00:00:00Z","timestamp":1724284800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21976174"],"award-info":[{"award-number":["21976174"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22076183"],"award-info":[{"award-number":["22076183"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22276189"],"award-info":[{"award-number":["22276189"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22276190"],"award-info":[{"award-number":["22276190"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ. Sci. Technol."],"published-print":{"date-parts":[[2024,9,3]]},"DOI":"10.1021\/acs.est.4c01341","type":"journal-article","created":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T21:53:13Z","timestamp":1724363593000},"page":"15428-15437","source":"Crossref","is-referenced-by-count":6,"title":["Medium-Chain Chlorinated Paraffins Trigger Thyroid Hormone Synthesis and Interfere with Mitochondrial Function in the Thyroid Gland"],"prefix":"10.1021","volume":"58","author":[{"given":"Lin","family":"Cheng","sequence":"first","affiliation":[{"name":"CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning 116023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuangshuang","family":"Chen","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning 116023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Luo","sequence":"additional","affiliation":[{"name":"College of Medicine, Linyi University, Linyi, Shandong 276005, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0974-2647","authenticated-orcid":true,"given":"Yuan","family":"Gao","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning 116023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Ren","sequence":"additional","affiliation":[{"name":"Safety Evaluation Center of Shenyang SYRICI Testing Co., Ltd., Shenyang, Liaoning 110141, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5567-7834","authenticated-orcid":true,"given":"Haijun","family":"Zhang","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning 116023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9404-1687","authenticated-orcid":true,"given":"Jiping","family":"Chen","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning 116023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0809-7463","authenticated-orcid":true,"given":"Ningbo","family":"Geng","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning 116023, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,8,22]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.emcon.2020.03.003"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.2c07548"},{"key":"ref3\/cit3","unstructured":"UNEP. Report of the Conference of the Parties\nto the Stockholm\nConvention on Persistent Organic Pollutants on the work of its eighth\nmeeting. In  POPRC; UNEP, 2017. http:\/\/chm.pops.int\/TheConvention\/ThePOPs\/TheNewPOPs\/tabid\/2511\/Default.aspx."},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2023.108020"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.0c07058"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.2c00264"},{"key":"ref7\/cit7","unstructured":"UNEP. Report of the Persistent Organic Pollutants Review\nCommittee on the work of its nineteenth meeting. In  POPRC.19\/9; UNEP, 2023. https:\/\/chm.pops.int\/TheConvention\/POPsReviewCommittee\/ReportsandDecisions\/tabid\/3309\/Default.aspx."},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2022.134230"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2021.131878"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-031-34087-1_10"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2019.04.016"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2019.04.065"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2021.116922"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2023.139131"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.3c08064"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.137998"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2020.115762"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2021.106514"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.8b02839"},{"key":"ref20\/cit20","doi-asserted-by":"crossref","DOI":"10.6027\/temanord2023-509","volume-title":"Human Exposure to Chlorinated Paraffins in Scandinavia: Association between Human Biomonitoring and External Exposures to SCCPs, MCCPs, and LCCPs in a Norwegian Cohort","author":"Yuan Bo.","year":"2023"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.yrtph.2014.02.002"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2020.110997"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/0300-483x(93)90139-j"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-021-02994-5"},{"key":"ref25\/cit25","volume-title":"Test No. 407: Repeated Dose 28-day Oral Toxicity Study in Rodents, OECD Guidelines for the Testing of Chemicals, Section 4","author":"OECD","year":"2008"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2021.127489"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2021.101562"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.0c03491"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.2903\/j.efsa.2020.5991"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/S0045-6535(99)00433-6"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2019.105231"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2021.129289"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2020.122590"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2020.124245"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.8b06350"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.4103\/0973-0354.99649"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.etp.2009.04.009"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2008.02.005"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1002\/jat.2550150607"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2017.02.012"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1210\/er.2013-1087"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1210\/en.2012-1727"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.3803\/EnM.2021.1198"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.12150"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1210\/er.2011-1050"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1007\/BF00352066"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(80)90179-9"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.2903\/j.efsa.2021.6877"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1186\/s12940-015-0029-4"},{"issue":"10","key":"ref50\/cit50","first-page":"20080","volume":"9","author":"Lv J.","year":"2016","journal-title":"Int. J. Clin Exp Med."},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2018.10.038"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.9b02810"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph14070723"},{"key":"ref54\/cit54","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/978-3-319-90725-3_3","volume-title":"Heat Shock Proteins and Stress","author":"Raghunath A.","year":"2018"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-15-0602-4_8"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.6b00567"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2017.11.020"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1042\/BSR20150295"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-0004(00)01609-1"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(06)53011-0"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19072017"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.2478\/enr-2021-0012"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1210\/er.2013-1006"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.2006.tb00186.x"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.03.012"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms9013"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0508556102"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.3390\/cells11071169"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2012.01.024"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1016\/j.teac.2022.e00161"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2019.05.047"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.9b04879"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2022.107195"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.0c03684"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2023.168192"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2024.134226"}],"container-title":["Environmental Science &amp; Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.4c01341","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.4c01341","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T08:32:03Z","timestamp":1725352323000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.est.4c01341"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,22]]},"references-count":76,"journal-issue":{"issue":"35","published-print":{"date-parts":[[2024,9,3]]}},"alternative-id":["10.1021\/acs.est.4c01341"],"URL":"https:\/\/doi.org\/10.1021\/acs.est.4c01341","relation":{},"ISSN":["0013-936X","1520-5851"],"issn-type":[{"value":"0013-936X","type":"print"},{"value":"1520-5851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,22]]}}}