{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T14:31:25Z","timestamp":1792765885279,"version":"4.5.0"},"reference-count":87,"publisher":"American Chemical Society (ACS)","issue":"17","license":[{"start":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T00:00:00Z","timestamp":1745193600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T00:00:00Z","timestamp":1745193600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T00:00:00Z","timestamp":1745193600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000146","name":"Division of Chemical, Bioengineering, Environmental, and Transport Systems","doi-asserted-by":"publisher","award":["CBET-1254929"],"award-info":[{"award-number":["CBET-1254929"]}],"id":[{"id":"10.13039\/100000146","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ. Sci. Technol."],"published-print":{"date-parts":[[2025,5,6]]},"DOI":"10.1021\/acs.est.4c10223","type":"journal-article","created":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T15:08:11Z","timestamp":1745248091000},"page":"8317-8328","source":"Crossref","is-referenced-by-count":7,"title":["Degradation and Deactivation of Intracellular Bacterial Antibiotic Resistance Genes by Commonly Used Healthcare and Personal Care Disinfectants"],"prefix":"10.1021","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0550-0974","authenticated-orcid":true,"given":"Huan","family":"He","sequence":"first","affiliation":[{"name":"State Key Laboratory of Pollution Control and Resource Reuse, Key Laboratory of Yangtze Water Environment, Ministry of Education, College of Environmental Science and Engineering","place":["Shanghai, P.R. China"]},{"name":"Tongji University","place":["Shanghai, P.R. China"]},{"name":"Department of Civil and Environmental Engineering","place":["Seattle, United States"]},{"name":"University of Washington","place":["Seattle, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1191-6041","authenticated-orcid":true,"given":"Sin-Yi","family":"Liou","sequence":"additional","affiliation":[{"name":"Department of Civil and Environmental Engineering","place":["Seattle, United States"]},{"name":"University of Washington","place":["Seattle, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8497-5945","authenticated-orcid":true,"given":"Kyle K.","family":"Shimabuku","sequence":"additional","affiliation":[{"name":"Department of Civil and Environmental Engineering","place":["Seattle, United States"]},{"name":"University of Washington","place":["Seattle, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peiran","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Civil and Environmental Engineering","place":["Seattle, United States"]},{"name":"University of Washington","place":["Seattle, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2177-1181","authenticated-orcid":true,"given":"Yegyun","family":"Choi","sequence":"additional","affiliation":[{"name":"School of Environment and Energy Engineering","place":["Gwangju, Republic of Korea"]},{"name":"Gwangju Institute of Science and Technology (GIST)","place":["Gwangju, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John S.","family":"Meschke","sequence":"additional","affiliation":[{"name":"Department of Environmental and Occupational Health Sciences","place":["Seattle, United States"]},{"name":"University of Washington","place":["Seattle, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilyn C.","family":"Roberts","sequence":"additional","affiliation":[{"name":"Department of Environmental and Occupational Health Sciences","place":["Seattle, United States"]},{"name":"University of Washington","place":["Seattle, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5923-4897","authenticated-orcid":true,"given":"Yunho","family":"Lee","sequence":"additional","affiliation":[{"name":"School of Environment and Energy Engineering","place":["Gwangju, Republic of Korea"]},{"name":"Gwangju Institute of Science and Technology (GIST)","place":["Gwangju, Republic of Korea"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7544-1642","authenticated-orcid":true,"given":"Michael C.","family":"Dodd","sequence":"additional","affiliation":[{"name":"Department of Civil and Environmental Engineering","place":["Seattle, United States"]},{"name":"University of Washington","place":["Seattle, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,4,21]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.00016-10"},{"key":"ref2\/cit2","volume-title":"Antibiotic Resistance Threats in the United States, 2013","volume":"2013"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.2c07503"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)02724-0"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1997.03550110082041"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.080239"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-021-01197-5"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1039\/D2EM00091A"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0122635"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2017.10.128"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2014.11.021"},{"key":"ref12\/cit12","volume-title":"Block\u2019s disinfection, sterilization, and preservation","author":"McDonnell G.","year":"2020","edition":"6"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1086\/597382"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkm520"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-019-0595-2"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2003.12.037"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2020.05.014"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-09575-1"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.0c05651"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.12.1.147"},{"key":"ref21\/cit21","unstructured":"Rutala, W. A.; Weber, D. J. Guideline for disinfection and sterilization in healthcare facilities, 2008; Centers for Disease Control and Prevention 2008; Update: June 2024."},{"key":"ref22\/cit22","volume-title":"Russell, Hugo and Ayliffe\u2019s principles and practice of disinfection, preservation and sterilization","author":"Fraise A. P.","year":"2013","edition":"5"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.0c05274"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.2c00567"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.8b04393"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/es303652q"},{"key":"ref27\/cit27","volume-title":"Russell, Hugo and Ayliffe\u2019s principles and practice of disinfection, preservation and sterilization","author":"Fraise A. P.","year":"2013","edition":"5"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2023.01.001"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/0195-6701(95)90044-6"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2008.03.004"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0152831"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2018.06.028"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1089\/mdr.2020.0543"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1080\/09603129509356839"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1139\/w05-130"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1038\/s41522-020-00140-0"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2019.103630"},{"key":"ref38\/cit38","volume-title":"Antibiotic resistance threats in the United States, 2019","year":"2019"},{"key":"ref39\/cit39","volume-title":"Disinfection, sterilization, and preservation","author":"Block S. S.","year":"2001"},{"key":"ref40\/cit40","doi-asserted-by":"crossref","unstructured":"Wendt, C.; Frei, R.; Widmer, A. F. In  Manual of Clinical Microbiology, 11th Edition; American Society of Microbiology, 2015; pp 183\u2013216.","DOI":"10.1128\/9781555817381.ch13"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1093\/jambio\/lxad244"},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1017\/ice.2019.161","volume":"40","author":"Boyce J. M.","year":"2019","journal-title":"Infect. Cont. Hosp. Ep."},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1128\/jb.177.14.3904-3910.1995"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1128\/jb.94.3.562-570.1967"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1128\/jb.81.5.741-746.1961"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/0926-6550(63)90386-4"},{"key":"ref47\/cit47","volume-title":"Quantitative method for evaluating bactericidal activity of microbicides used on hard non-porous surfaces","year":"2013"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1053\/jhin.2000.0805"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2019.04.001"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/S0964-8305(98)00020-1"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2007.07.026"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1021\/j150497a007"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1111\/j.1745-4581.2009.00182.x"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1023\/A:1010072226737"},{"key":"ref55\/cit55","doi-asserted-by":"crossref","unstructured":"Bustin, S. A.; Benes, V.; Garson, J. A.; Hellemans, J.; Huggett, J.; Kubista, M.; Mueller, R.; Nolan, T.; Pfaffl, M. W.; Shipley, G. L. The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments; Oxford University Press, 2009","DOI":"10.1373\/clinchem.2008.112797"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2006.03.071"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.5b02385"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.1c00939"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1128\/jb.169.8.3601-3607.1987"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1039\/c2em00006g"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2023.119626"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1039\/b201230h"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1039\/c3pp50078k"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2025263118"},{"key":"ref65\/cit65","volume-title":"Alternative disinfectants and oxidants guidance manual","year":"1999"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.275.15.10851"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1128\/aem.59.11.3545-3550.1993"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.4014\/jmb.2211.11027"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2022.118379"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-3841.2011.02476.x"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.4315\/0362-028X-59.11.1233"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2787(72)90509-6"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-405881-1.00001-X"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.3109\/10715768909073427"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.micro.57.030502.090938"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.1089\/dna.2005.24.394"},{"key":"ref77\/cit77","doi-asserted-by":"publisher","DOI":"10.1039\/D2DT03168J"},{"key":"ref78\/cit78","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(90)80651-X"},{"key":"ref79\/cit79","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.17.9738"},{"key":"ref80\/cit80","doi-asserted-by":"publisher","DOI":"10.1080\/10643380500326564"},{"key":"ref81\/cit81","doi-asserted-by":"publisher","DOI":"10.1021\/tx0002278"},{"key":"ref82\/cit82","doi-asserted-by":"publisher","DOI":"10.1006\/abbi.1996.0322"},{"key":"ref83\/cit83","doi-asserted-by":"publisher","DOI":"10.1016\/0147-619X(79)90054-4"},{"key":"ref84\/cit84","unstructured":"Dubnau, D. In  Bacillus subtilis and other gram-positive bacteria: biochemistry, physiology, and molecular genetics. Sonenshein, A. L., Hoch, J. A., Losick, R., Eds. American Society for Microbiology: Washington D.C, 1993; pp 555\u2013584."},{"key":"ref85\/cit85","doi-asserted-by":"publisher","DOI":"10.1128\/jb.112.1.220-223.1972"},{"key":"ref86\/cit86","doi-asserted-by":"publisher","DOI":"10.1086\/507964"},{"key":"ref87\/cit87","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2020.04.011"}],"container-title":["Environmental Science &amp; Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.4c10223","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.4c10223","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T08:12:57Z","timestamp":1746519177000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.est.4c10223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,21]]},"references-count":87,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2025,5,6]]}},"alternative-id":["10.1021\/acs.est.4c10223"],"URL":"https:\/\/doi.org\/10.1021\/acs.est.4c10223","relation":{},"ISSN":["0013-936X","1520-5851"],"issn-type":[{"value":"0013-936X","type":"print"},{"value":"1520-5851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,21]]}}}