{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T08:36:57Z","timestamp":1791362217057,"version":"4.3.1"},"reference-count":70,"publisher":"American Chemical Society (ACS)","issue":"5","license":[{"start":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T00:00:00Z","timestamp":1738195200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T00:00:00Z","timestamp":1738195200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T00:00:00Z","timestamp":1738195200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51925901"],"award-info":[{"award-number":["51925901"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52330005"],"award-info":[{"award-number":["52330005"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ. Sci. Technol."],"published-print":{"date-parts":[[2025,2,11]]},"DOI":"10.1021\/acs.est.4c12926","type":"journal-article","created":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T02:42:21Z","timestamp":1738291341000},"page":"2815-2826","source":"Crossref","is-referenced-by-count":39,"title":["Incorporating Transformation Products for an Integrated Assessment of Antibiotic Pollution and Risks in Surface Water"],"prefix":"10.1021","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0626-8046","authenticated-orcid":true,"given":"Jingrun","family":"Hu","sequence":"first","affiliation":[{"name":"Key Laboratory of Water and Sediment Sciences, Ministry of Education, College of Environmental Sciences and Engineering","place":["Beijing, China"]},{"name":"Peking University","place":["Beijing, China"]},{"name":"State Environmental Protection Key Laboratory of All Material Fluxes in River Ecosystems","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yitao","family":"Lyu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Water and Sediment Sciences, Ministry of Education, College of Environmental Sciences and Engineering","place":["Beijing, China"]},{"name":"Peking University","place":["Beijing, China"]},{"name":"State Environmental Protection Key Laboratory of All Material Fluxes in River Ecosystems","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Water and Sediment Sciences, Ministry of Education, College of Environmental Sciences and Engineering","place":["Beijing, China"]},{"name":"Peking University","place":["Beijing, China"]},{"name":"State Environmental Protection Key Laboratory of All Material Fluxes in River Ecosystems","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuqi","family":"You","sequence":"additional","affiliation":[{"name":"Key Laboratory of Water and Sediment Sciences, Ministry of Education, College of Environmental Sciences and Engineering","place":["Beijing, China"]},{"name":"Peking University","place":["Beijing, China"]},{"name":"State Environmental Protection Key Laboratory of All Material Fluxes in River Ecosystems","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2588-145X","authenticated-orcid":true,"given":"Damian E.","family":"Helbling","sequence":"additional","affiliation":[{"name":"School of Civil and Environmental Engineering","place":["Ithaca, United States"]},{"name":"Cornell University","place":["Ithaca, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5064-0351","authenticated-orcid":true,"given":"Weiling","family":"Sun","sequence":"additional","affiliation":[{"name":"Key Laboratory of Water and Sediment Sciences, Ministry of Education, College of Environmental Sciences and Engineering","place":["Beijing, China"]},{"name":"Peking University","place":["Beijing, China"]},{"name":"State Environmental Protection Key Laboratory of All Material Fluxes in River Ecosystems","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,1,30]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2113947119"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1360\/nso\/20220029"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-021-00649-x"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2008.11.086"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.8b00299"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1080\/10643389.2022.2045159"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.9b01131"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.4902"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2019.114972"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/es040624v"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/es1030799"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/es2034125"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.4c00125"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/acsenvironau.1c00008"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.3c05008"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2022.119509"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2020.105599"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/es901979h"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.21105\/joss.04029"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.5b02905"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2014.11.009"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1186\/s13321-018-0324-5"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.4c00968"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1186\/s13321-016-0115-9"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku436"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1002\/jms.1777"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2021.146562"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.2c09854"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2017.06.005"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acsenvironau.2c00024"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1186\/s12302-022-00604-4"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1186\/s12302-024-00919-4"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.2c07774"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2021.10.005"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2017.09.013"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.5b00302"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2020.105796"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-021-17723-9"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.8b00945"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1021\/es5002105"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.4c01201"},{"key":"ref42\/cit42","unstructured":"European\nCommission Amending regulation (EC)\nNo 1272\/2008 as\nregards hazard classes and criteria for the classification, labelling\nand packaging of substances and mixtures. https:\/\/eur-lex.europa.eu\/legal-content\/EN\/TXT\/?uri=celex%3A32023R0707 (Accessed on 11 September 2024)."},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1039\/C7EM00064B"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1186\/s13321-018-0263-1"},{"key":"ref45\/cit45","unstructured":"US\nEPA Ecological Structure - Activity\nRelationships Program (ECOSAR)\nMethodology Document v2.0. https:\/\/www.epa.gov\/tsca-screening-tools\/ecological-structure-activity-relationships-program-ecosar-methodology (Accessed on 12 Juanuary 2025)."},{"key":"ref46\/cit46","unstructured":"European Commission, Technical\nGuidance Document on Risk Assessment in support of Commission Directive\n93\/67\/EEC on Risk Assessment for new notified substances, Commission\nRegulation (EC) No 1488\/94 on Risk Assessment for existing substances,\nand Directive 98\/8\/EC of the European Parliament and of the Council\nconcerning the placing of biocidal products on the market. Directive 98\/8\/EC of the European Parliament\nand of the Council Concerning the Placing of Biocidal Products on\nthe Market 2003."},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2015.10.015"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btn307"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/acsestwater.4c00240"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2017.09.328"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.5b00729"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.4c02902"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2024.135399"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2023.120214"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2015.09.017"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.0c02328"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.9b06114"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1021\/jp073030y"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1021\/bi201790u"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-59745-180-2_8"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2018.01.055"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1039\/C4AY00708E"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1002\/jps.20023"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1021\/acsestwater.0c00239"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.154647"},{"key":"ref66\/cit66","unstructured":"World\nHealth Organization WHO List of Medically\nImportant Antimicrobials:\nA risk management tool for mitigating antimicrobial resistance due\nto non-human use. https:\/\/cdn.who.int\/media\/docs\/default-source\/gcp\/who-mia-list-2024-lv.pdf?sfvrsn=3320dd3d_2 (Accessed on 8 January 2025)."},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1021\/es500371t"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.0c06625"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2021.106885"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.3c01744"}],"container-title":["Environmental Science &amp; Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.4c12926","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.4c12926","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T09:28:09Z","timestamp":1739266089000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.est.4c12926"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,30]]},"references-count":70,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,2,11]]}},"alternative-id":["10.1021\/acs.est.4c12926"],"URL":"https:\/\/doi.org\/10.1021\/acs.est.4c12926","relation":{},"ISSN":["0013-936X","1520-5851"],"issn-type":[{"value":"0013-936X","type":"print"},{"value":"1520-5851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,30]]}}}