{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T14:22:55Z","timestamp":1777213375233,"version":"3.51.4"},"reference-count":59,"publisher":"American Chemical Society (ACS)","issue":"19","license":[{"start":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T00:00:00Z","timestamp":1746489600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T00:00:00Z","timestamp":1746489600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T00:00:00Z","timestamp":1746489600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["1P01ES028942"],"award-info":[{"award-number":["1P01ES028942"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007492","name":"Baylor University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007492","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000139","name":"U.S. Environmental Protection Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000139","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["CBET-2042060"],"award-info":[{"award-number":["CBET-2042060"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ. Sci. Technol."],"published-print":{"date-parts":[[2025,5,20]]},"DOI":"10.1021\/acs.est.5c02446","type":"journal-article","created":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T13:25:59Z","timestamp":1746537959000},"page":"9497-9506","source":"Crossref","is-referenced-by-count":1,"title":["Inhibition of Fin Regeneration in Fathead Minnow (<i>Pimephales promelas<\/i>) by a Potent Synthetic Glucocorticoid and Development of Adverse Outcome Pathway 334"],"prefix":"10.1021","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4608-2518","authenticated-orcid":true,"given":"Alexander R.","family":"Cole","sequence":"first","affiliation":[{"name":"Department of Environmental Science, Center for Reservoir and Aquatic Systems Research","place":["Waco, United States"]},{"name":"Baylor University","place":["Waco, United States"]},{"name":"Great Lakes Toxicology and Ecology Division","place":["Duluth, United States"]},{"name":"US Environmental Protection Agency","place":["Duluth, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9937-615X","authenticated-orcid":true,"given":"Gerald T.","family":"Ankley","sequence":"additional","affiliation":[{"name":"Great Lakes Toxicology and Ecology Division","place":["Duluth, United States"]},{"name":"US Environmental Protection Agency","place":["Duluth, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7883-4740","authenticated-orcid":true,"given":"Jenna E.","family":"Cavallin","sequence":"additional","affiliation":[{"name":"Great Lakes Toxicology and Ecology Division","place":["Duluth, United States"]},{"name":"US Environmental Protection Agency","place":["Duluth, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob R.","family":"Collins","sequence":"additional","affiliation":[{"name":"Great Lakes Toxicology and Ecology Division","place":["Duluth, United States"]},{"name":"Oak Ridge Institute for Science and Education, US EPA","place":["Duluth, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen M.","family":"Jensen","sequence":"additional","affiliation":[{"name":"Great Lakes Toxicology and Ecology Division","place":["Duluth, United States"]},{"name":"US Environmental Protection Agency","place":["Duluth, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael D.","family":"Kahl","sequence":"additional","affiliation":[{"name":"Great Lakes Toxicology and Ecology Division","place":["Duluth, United States"]},{"name":"US Environmental Protection Agency","place":["Duluth, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex J.","family":"Kasparek","sequence":"additional","affiliation":[{"name":"Great Lakes Toxicology and Ecology Division","place":["Duluth, United States"]},{"name":"Oak Ridge Institute for Science and Education, US EPA","place":["Duluth, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ba Reum","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Environmental Science, Center for Reservoir and Aquatic Systems Research","place":["Waco, United States"]},{"name":"Baylor University","place":["Waco, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yesmeena M.","family":"Shmaitelly","sequence":"additional","affiliation":[{"name":"Department of Environmental Science, Center for Reservoir and Aquatic Systems Research","place":["Waco, United States"]},{"name":"Baylor University","place":["Waco, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2095-7163","authenticated-orcid":true,"given":"Laura M.","family":"Langan","sequence":"additional","affiliation":[{"name":"Department of Environmental Science, Center for Reservoir and Aquatic Systems Research","place":["Waco, United States"]},{"name":"Baylor University","place":["Waco, United States"]},{"name":"Department of Environmental Health Sciences","place":["Columbia, United States"]},{"name":"University of South Carolina","place":["Columbia, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2801-0203","authenticated-orcid":true,"given":"Daniel L.","family":"Villeneuve","sequence":"additional","affiliation":[{"name":"Great Lakes Toxicology and Ecology Division","place":["Duluth, United States"]},{"name":"US Environmental Protection Agency","place":["Duluth, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6277-9852","authenticated-orcid":true,"given":"Bryan W.","family":"Brooks","sequence":"additional","affiliation":[{"name":"Department of Environmental Science, Center for Reservoir and Aquatic Systems Research","place":["Waco, United States"]},{"name":"Baylor University","place":["Waco, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2025,5,6]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.1002180"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2021.111904"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2023.121638"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1021\/es072658j"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1159\/000359984"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/acsestwater.3c00253"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/S0049-0172(05)80029-0"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1530\/JME-18-0024"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1080\/10641260390255745"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.084244"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2014.01.010"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.tig.2015.03.012"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfl103"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1093\/etojnl\/vgae041"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxrep.2019.05.013"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpc.2012.05.003"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0531290100"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1159\/000259327"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1002\/reg2.33"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/wdev.367"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2013.04.091"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2018.07.190"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.0c05269"},{"key":"ref24\/cit24","volume-title":"Fundamentals of Biostatistics","author":"Rosner B.","year":"2010","edition":"7"},{"key":"ref25\/cit25","doi-asserted-by":"crossref","DOI":"10.47886\/9780913235584","volume-title":"Methods for Fish Biology","author":"Schreck C. B.","year":"1990"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2089"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2021.117928"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.7150\/ijms.26741"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2017.03.042"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1006\/meth.2001.1262"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.149583"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1096\/fj.14-254755"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2014.00169"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2015.00170"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.3109\/03008207.2015.1077239"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2022.819682"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(01)00622-5"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-110571"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2023.107451"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1186\/1476-4598-8-83"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.98.12061327"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1211\/0022357001774174"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1007\/s40572-014-0029-5"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1002\/etc.2406"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.14573\/altex.1601281"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1677\/joe.1.06703"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2013.07.009"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2022.1048008"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1677\/jme.0.0310141"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1210\/en.2004-1390"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2007.05.019"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-004-1307-8"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2015.05.020"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2019.04.023"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1002\/etc.4231"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1039\/D0NJ03640D"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1007\/s10750-004-0189-7"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2013.0586"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1038\/nature09440"}],"container-title":["Environmental Science &amp; Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.5c02446","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.5c02446","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T11:10:35Z","timestamp":1747739435000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.est.5c02446"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,6]]},"references-count":59,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2025,5,20]]}},"alternative-id":["10.1021\/acs.est.5c02446"],"URL":"https:\/\/doi.org\/10.1021\/acs.est.5c02446","relation":{},"ISSN":["0013-936X","1520-5851"],"issn-type":[{"value":"0013-936X","type":"print"},{"value":"1520-5851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,6]]}}}