{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T20:19:06Z","timestamp":1778185146005,"version":"3.51.4"},"reference-count":36,"publisher":"American Chemical Society (ACS)","issue":"11","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"The Sanming Project of Medicine in Shenzhen","award":["SZSM202311015"],"award-info":[{"award-number":["SZSM202311015"]}]},{"name":"the Science and Technology Program of Guangdong","award":["2025A0505080007"],"award-info":[{"award-number":["2025A0505080007"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["82373704"],"award-info":[{"award-number":["82373704"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Shenzhen Science and Technology Program","award":["KCXFZ20230731093959008"],"award-info":[{"award-number":["KCXFZ20230731093959008"]}]},{"name":"Shenzhen Science and Technology Program","award":["SYSPG20241211173921049"],"award-info":[{"award-number":["SYSPG20241211173921049"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ. Sci. Technol."],"published-print":{"date-parts":[[2026,3,24]]},"DOI":"10.1021\/acs.est.5c02652","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T10:31:50Z","timestamp":1773138710000},"page":"8315-8325","source":"Crossref","is-referenced-by-count":1,"title":["Cost-Effective Sampling Strategies for Wastewater Surveillance: A Large-Scale Longitudinal Study in Hong Kong and Shenzhen"],"prefix":"10.1021","volume":"60","author":[{"given":"Xiawan","family":"Zheng","sequence":"first","affiliation":[{"name":"Environmental Microbiome Engineering and Biotechnology Laboratory, Center for Environmental Engineering Research, Department of Civil Engineering","place":["Pokfulam, China"]},{"name":"The University of Hong Kong","place":["Pokfulam, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yinghui","family":"Li","sequence":"additional","affiliation":[{"name":"Shenzhen Center for Disease Control and Prevention","place":["Shenzhen, China"]},{"name":"School of Public Health","place":["Guangzhou, China"]},{"name":"Southern Medical University","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Deng","sequence":"additional","affiliation":[{"name":"Environmental Microbiome Engineering and Biotechnology Laboratory, Center for Environmental Engineering Research, Department of Civil Engineering","place":["Pokfulam, China"]},{"name":"The University of Hong Kong","place":["Pokfulam, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bincai","family":"Wei","sequence":"additional","affiliation":[{"name":"School of Public Health and Emergency Management","place":["Shenzhen, China"]},{"name":"Southern University of Science and Technology","place":["Shenzhen, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoqing","family":"Xu","sequence":"additional","affiliation":[{"name":"Environmental Microbiome Engineering and Biotechnology Laboratory, Center for Environmental Engineering Research, Department of Civil Engineering","place":["Pokfulam, China"]},{"name":"The University of Hong Kong","place":["Pokfulam, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen","family":"Du","sequence":"additional","affiliation":[{"name":"Shenzhen Center for Disease Control and Prevention","place":["Shenzhen, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guixian","family":"Luo","sequence":"additional","affiliation":[{"name":"Shenzhen Center for Disease Control and Prevention","place":["Shenzhen, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miaomiao","family":"Luo","sequence":"additional","affiliation":[{"name":"Shenzhen Center for Disease Control and Prevention","place":["Shenzhen, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuyuan","family":"Shi","sequence":"additional","affiliation":[{"name":"School of Public Health and Emergency Management","place":["Shenzhen, China"]},{"name":"Southern University of Science and Technology","place":["Shenzhen, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuejing","family":"Peng","sequence":"additional","affiliation":[{"name":"Shenzhen Center for Disease Control and Prevention","place":["Shenzhen, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuxian","family":"Li","sequence":"additional","affiliation":[{"name":"Environmental Microbiome Engineering and Biotechnology Laboratory, Center for Environmental Engineering Research, Department of Civil Engineering","place":["Pokfulam, China"]},{"name":"The University of Hong Kong","place":["Pokfulam, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiahui","family":"Ding","sequence":"additional","affiliation":[{"name":"Environmental Microbiome Engineering and Biotechnology Laboratory, Center for Environmental Engineering Research, Department of Civil Engineering","place":["Pokfulam, China"]},{"name":"The University of Hong Kong","place":["Pokfulam, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bingjie","family":"Xue","sequence":"additional","affiliation":[{"name":"Environmental Microbiome Engineering and Biotechnology Laboratory, Center for Environmental Engineering Research, Department of Civil Engineering","place":["Pokfulam, China"]},{"name":"The University of Hong Kong","place":["Pokfulam, China"]},{"name":"College of Chemistry and Environmental Engineering","place":["Shenzhen, China"]},{"name":"Shenzhen University","place":["Shenzhen, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanping","family":"Mao","sequence":"additional","affiliation":[{"name":"College of Chemistry and Environmental Engineering","place":["Shenzhen, China"]},{"name":"Shenzhen University","place":["Shenzhen, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qinghua","family":"Hu","sequence":"additional","affiliation":[{"name":"Shenzhen Center for Disease Control and Prevention","place":["Shenzhen, China"]},{"name":"School of Public Health and Emergency Management","place":["Shenzhen, China"]},{"name":"Southern University of Science and Technology","place":["Shenzhen, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1148-4322","authenticated-orcid":true,"given":"Tong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Environmental Microbiome Engineering and Biotechnology Laboratory, Center for Environmental Engineering Research, Department of Civil Engineering","place":["Pokfulam, China"]},{"name":"The University of Hong Kong","place":["Pokfulam, China"]},{"name":"School of Public Health, LKS Faculty of Medicine","place":["Pokfulam, China"]},{"name":"The University of Hong Kong","place":["Pokfulam, China"]},{"name":"Department of Environmental Science and Engineering","place":["Taipa, China"]},{"name":"Macau University of Science and Technology","place":["Taipa, China"]},{"name":"Shenzhen Innovation and Research Institute","place":["Shenzhen, China"]},{"name":"The University of Hong Kong","place":["Shenzhen, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2026,3,6]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-020-0684-z"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2024.121513"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-5247(23)00010-1"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-05049-6"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-28246-3"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-40305-x"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-31753-y"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1093\/femsmc\/xtad003"},{"key":"ref9\/cit9","volume-title":"Environmental surveillance for SARS-COV-2 to complement public health surveillance","author":"World Health Organization","year":"2023"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.157121"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acsestwater.1c00160"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.eng.2024.01.016"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2024.175235"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2024.175830"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2022.119560"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.1c01767"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.1c03589"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.1c05029"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/acs.estlett.2c00693"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2024.171566"},{"key":"ref21\/cit21","volume-title":"SARS-CoV-2 surveillance employing sewage: Towards a sentinel system","author":"Gawlik B.","year":"2021"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2119600119"},{"key":"ref23\/cit23","unstructured":"Capacity Building Program to Develop a Wastewater-Based\nEpidemiology\nFramework for COVID-19: Case Studies from Ecuador and Uruguay (English)\n                      ; World Bank Group: Washington, D.C., 2021. http:\/\/documents.worldbank.org\/curated\/en\/847141634797552065."},{"key":"ref24\/cit24","unstructured":"Developing a Wastewater Surveillance Sampling Strategy\n                      ; US CDC, 2024. https:\/\/archive.cdc.gov\/www_cdc_gov\/nwss\/sampling.html."},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1289\/EHP8572"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.scib.2022.04.006"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acs.estlett.1c00882"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.143493"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.4c02638"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2023.120573"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2022.118904"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2221887120"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1910242116"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1289\/EHP9966"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/acs.estlett.1c00519"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.lana.2023.100449"}],"container-title":["Environmental Science &amp; Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.5c02652","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.5c02652","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T08:13:23Z","timestamp":1774340003000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.est.5c02652"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,6]]},"references-count":36,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,3,24]]}},"alternative-id":["10.1021\/acs.est.5c02652"],"URL":"https:\/\/doi.org\/10.1021\/acs.est.5c02652","relation":{},"ISSN":["0013-936X","1520-5851"],"issn-type":[{"value":"0013-936X","type":"print"},{"value":"1520-5851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,6]]}}}