{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T22:13:34Z","timestamp":1780092814869,"version":"3.54.0"},"reference-count":57,"publisher":"American Chemical Society (ACS)","issue":"4","license":[{"start":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:00:00Z","timestamp":1768867200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:00:00Z","timestamp":1768867200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:00:00Z","timestamp":1768867200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22376226"],"award-info":[{"award-number":["22376226"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22425607"],"award-info":[{"award-number":["22425607"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["42307308"],"award-info":[{"award-number":["42307308"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["S2013030013474"],"award-info":[{"award-number":["S2013030013474"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ. Sci. Technol."],"published-print":{"date-parts":[[2026,2,3]]},"DOI":"10.1021\/acs.est.5c12017","type":"journal-article","created":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T21:44:23Z","timestamp":1768945463000},"page":"3486-3496","source":"Crossref","is-referenced-by-count":1,"title":["Stable Isotopic Labeling and Automated Reactivity-Directed Approach Accelerating Discovery of Toxic Disinfection Byproducts in Chlorinated and Chloraminated Waters"],"prefix":"10.1021","volume":"60","author":[{"given":"Yijia","family":"Sun","sequence":"first","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology, School of Environmental Science and Engineering","place":["Guangzhou, China"]},{"name":"Sun Yat-sen University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6036-5513","authenticated-orcid":true,"given":"Yangjian","family":"Zhou","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology, School of Environmental Science and Engineering","place":["Guangzhou, China"]},{"name":"Sun Yat-sen University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuemei","family":"Chen","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Bioinorganic and Synthetic Chemistry\/KLGHEI of Environment and Energy Chemistry, School of Chemistry, Institute of Green Chemistry and Molecular Engineering","place":["Guangzhou, China"]},{"name":"Sun Yat-sen University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyan","family":"Xie","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology, School of Environmental Science and Engineering","place":["Guangzhou, China"]},{"name":"Sun Yat-sen University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0326-5325","authenticated-orcid":true,"given":"Junlang","family":"Qiu","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology, School of Environmental Science and Engineering","place":["Guangzhou, China"]},{"name":"Sun Yat-sen University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6939-9975","authenticated-orcid":true,"given":"Fang","family":"Zhu","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Bioinorganic and Synthetic Chemistry\/KLGHEI of Environment and Energy Chemistry, School of Chemistry, Institute of Green Chemistry and Molecular Engineering","place":["Guangzhou, China"]},{"name":"Sun Yat-sen University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0797-6036","authenticated-orcid":true,"given":"Gangfeng","family":"Ouyang","sequence":"additional","affiliation":[{"name":"MOE Key Laboratory of Bioinorganic and Synthetic Chemistry\/KLGHEI of Environment and Energy Chemistry, School of Chemistry, Institute of Green Chemistry and Molecular Engineering","place":["Guangzhou, China"]},{"name":"Sun Yat-sen University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9860-423X","authenticated-orcid":true,"given":"Xin","family":"Yang","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology, School of Environmental Science and Engineering","place":["Guangzhou, China"]},{"name":"Sun Yat-sen University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,1,20]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.7b05440"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.2c01017"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1134\/S1061934822140052"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2019.07.014"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1289\/EHP9985"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2023.122601"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.1c04640"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclepro.2020.123159"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jece.2020.103939"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.8b06711"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/s44221-025-00468-x"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.3c00056"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1039\/D0EM00471E"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.3109\/10408449209146310"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.3109\/10408444.2010.494175"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.9b04926"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.2c05486"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1715821115"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.7b02184"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.9b03642"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.9b04875"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1038\/s44221-024-00381-9"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1007\/s11306-018-1336-x"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/ac5009089"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/ac403384n"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jes.2023.02.033"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.5b04783"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.8b01675"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.4c05165"},{"key":"ref30\/cit30","unstructured":"Frisch, M. J.; Trucks, G. W.; Schlegel, H. B.; Scuseria, G. E.; Robb, M. A.; Cheeseman, J. R.; Scalmani, G.; Barone, V.; Mennucci, B.; Petersson, G. A.; Nakatsuji, H.; Caricato, M.; Li, X.; Hratchian, H. P.; Izmaylov, A. F.; Bloino, J.; Zheng, G.; Sonnenberg, J. L.; Hada, M.; Ehara, M.; Toyota, K.; Fukuda, R.; Hasegawa, J.; Ishida, M.; Nakajima, T.; Honda, Y.; Kitao, O.; Nakai, H.; Vreven, T.; Montgomery, J. A., Jr.; Peralta, J. E.; Ogliaro, F.; Bearpark, M.; Heyd, J. J.; Brothers, E.; Kudin, K. N.; Staroverov, V. N.; Keith, T.; Kobayashi, R.; Normand, J.; Raghavachari, K.; Rendell, A.; Burant, J. C.; Iyengar, S. S.; Tomasi, J.; Cossi, M.; Rega, N.; Millam, J. M.; Klene, M.; Knox, J. E.; Cross, J. B.; Bakken, V.; Adamo, C.; Jaramillo, J.; Gomperts, R.; Stratmann, R. E.; Yazyev, O.; Austin, A. J.; Cammi, R.; Pomelli, C.; Ochterski, J. W.; Martin, R. L.; Morokuma, K.; Zakrzewski, V. G.; Voth, G. A.; Salvador, P.; annenberg, J. J.; Dapprich, S.; Daniels, A. D.; Farkas, O.; Foresman, J. B.; Ortiz, J. V.; Cioslowski, J.; Fox, D. J.\n                      Gaussian 09, Revision D.01\n                      ; Gaussian, Inc.: Wallingford, CT, 2013."},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1039\/D1CP02805G"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1063\/5.0216272"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.22885"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/0263-7855(96)00018-5"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2014.09.013"},{"key":"ref36\/cit36","unstructured":"United Nations.\n                      Globally Harmonized System of Classification and Labelling\nof Chemicals (GHS)\n                      , 10th ed. United Nations: New York, 2023."},{"key":"ref37\/cit37","unstructured":"Organisation for Economic Co-operation\nand Development (OECD). Test\nNo. 202:\n                      Daphnia\n                      sp. Acute Immobilisation Test.\n                      OECD Guidelines for the Testing of Chemicals\n                      ; OECD: Paris, France, 2006."},{"key":"ref38\/cit38","unstructured":"Organisation for Economic Co-operation\nand Development (OECD). Test\nNo. 203: Fish, Acute Toxicity Test.\n                      OECD Guidelines\nfor the Testing of Chemicals\n                      ; OECD: Paris, France, 2002."},{"key":"ref39\/cit39","unstructured":"Organisation\nfor Economic Co-operation\nand Development (OECD). Test\nNo. 420: Acute Oral Toxicity\u2500Fixed Dose Procedure.\n                      OECD Guidelines for the Testing of Chemicals\n                      ; OECD: Paris, France, 2006; Vol. 1 (4),\npp 1\u201314."},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1021\/ac051437y"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.1c01644"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5b13140"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2023.132792"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1021\/es5002105"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1039\/D0EW00300J"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c10296"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202304023"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1139\/a06-005"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1038\/s44221-023-00064-x"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.3c00771"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1021\/es502855x"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2025.123981"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.1c00078"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2025.123786"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2023.162815"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2015.11.002"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2012.11.046"}],"container-title":["Environmental Science & Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.5c12017","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.5c12017","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T09:16:11Z","timestamp":1770110171000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.est.5c12017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,20]]},"references-count":57,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,2,3]]}},"alternative-id":["10.1021\/acs.est.5c12017"],"URL":"https:\/\/doi.org\/10.1021\/acs.est.5c12017","relation":{},"ISSN":["0013-936X","1520-5851"],"issn-type":[{"value":"0013-936X","type":"print"},{"value":"1520-5851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,20]]}}}