{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T14:47:38Z","timestamp":1788792458246,"version":"build-2803163510"},"reference-count":63,"publisher":"American Chemical Society (ACS)","issue":"7","license":[{"start":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T00:00:00Z","timestamp":1770854400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T00:00:00Z","timestamp":1770854400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T00:00:00Z","timestamp":1770854400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100010256","name":"Guangzhou Municipal Science and Technology Project","doi-asserted-by":"publisher","award":["2024A04J6476"],"award-info":[{"award-number":["2024A04J6476"]}],"id":[{"id":"10.13039\/501100010256","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Basic Research Program of China (973 Program)","doi-asserted-by":"crossref","award":["2024YFC3712003"],"award-info":[{"award-number":["2024YFC3712003"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["42107468"],"award-info":[{"award-number":["42107468"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China (NSFC)","doi-asserted-by":"crossref","award":["82574042"],"award-info":[{"award-number":["82574042"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ. Sci. Technol."],"published-print":{"date-parts":[[2026,2,24]]},"DOI":"10.1021\/acs.est.5c16736","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T13:50:07Z","timestamp":1770904207000},"page":"5363-5377","source":"Crossref","is-referenced-by-count":3,"title":["Early F-53B Exposure Induces Autism Spectrum Disorder-like Hypomyelination and Oligodendrocytes-Derived Exosomal Protein-Dependent Axonal Energy Imbalance"],"prefix":"10.1021","volume":"60","author":[{"given":"Shen-Pan","family":"Li","sequence":"first","affiliation":[{"name":"Joint International Research Laboratory of Environment and Health, Ministry of Education, Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health","place":["Guangzhou, China"]},{"name":"Sun Yat-Sen University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2249-5811","authenticated-orcid":true,"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Joint International Research Laboratory of Environment and Health, Ministry of Education, Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health","place":["Guangzhou, China"]},{"name":"Sun Yat-Sen University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2204-7727","authenticated-orcid":true,"given":"Wen-Hui","family":"Zhao","sequence":"additional","affiliation":[{"name":"Joint International Research Laboratory of Environment and Health, Ministry of Education, Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health","place":["Guangzhou, China"]},{"name":"Sun Yat-Sen University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su-Qin","family":"Tan","sequence":"additional","affiliation":[{"name":"Joint International Research Laboratory of Environment and Health, Ministry of Education, Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health","place":["Guangzhou, China"]},{"name":"Sun Yat-Sen University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua-Lian","family":"Chen","sequence":"additional","affiliation":[{"name":"Joint International Research Laboratory of Environment and Health, Ministry of Education, Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health","place":["Guangzhou, China"]},{"name":"Sun Yat-Sen University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing-Yu","family":"Chen","sequence":"additional","affiliation":[{"name":"Joint International Research Laboratory of Environment and Health, Ministry of Education, Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health","place":["Guangzhou, China"]},{"name":"Sun Yat-Sen University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Joint International Research Laboratory of Environment and Health, Ministry of Education, Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health","place":["Guangzhou, China"]},{"name":"Sun Yat-Sen University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Cai","sequence":"additional","affiliation":[{"name":"Department of Public Health and Preventive Medicine, School of Medicine","place":["Guangzhou, China"]},{"name":"Jinan University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2578-3369","authenticated-orcid":true,"given":"Guang-Hui","family":"Dong","sequence":"additional","affiliation":[{"name":"Joint International Research Laboratory of Environment and Health, Ministry of Education, Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health","place":["Guangzhou, China"]},{"name":"Sun Yat-Sen University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3918-1841","authenticated-orcid":true,"given":"Xiao-Wen","family":"Zeng","sequence":"additional","affiliation":[{"name":"Joint International Research Laboratory of Environment and Health, Ministry of Education, Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health","place":["Guangzhou, China"]},{"name":"Sun Yat-Sen University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,2,12]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2022.107108"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2021.152446"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1289\/EHP4431"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.6b06049"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.5b05849"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.9b03820"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2019.135885"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.8b04550"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.4c05405"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/envhealth.4c00098"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2023.108272"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/envhealth.4c00158"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.2c07807"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2023.107850"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.4c04500"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.23661"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-019-0578-x"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.eehl.2024.08.002"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2023.108211"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2022.107379"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanplh.2025.101309"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2025.103758"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2024.120638"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2021.08.011"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1038\/s41583-023-00711-y"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-022-00737-3"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2023.106965"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3000621"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1111\/cns.14661"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2021.106986"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2022.118960"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jes.2024.03.034"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2024.118305"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2025.137751"},{"key":"ref35\/cit35","unstructured":"EPA.\n                      Health Effects Support\nDocument for Perfluorooctane Sulfonate (PFOS)\n                      ; US EPA, Office of Water: Washington,\nDC; 2016."},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.7b02102"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2016.09.017"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.1c00616"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24010894"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2024.106601"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2023.132074"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2025.115360"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1039\/D1EM00228G"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00007-10"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2024.176941"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2020.116376"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2025.121128"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2023.121479"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-23201-0"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2025.137111"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.24241"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2023.102722"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","unstructured":"Kong, A. X.; Johnson, M.; Eno, A. F.; Pham, K.; Zhang, P.; Geng, Y.Proteome-wide reverse molecular docking reveals folic acid receptor as a mediator of PFAS-induced neurodevelopmental toxicity\n                      bioRxiv\n                      202462308210.1101\/2024.11.11.623082.","DOI":"10.1101\/2024.11.11.623082"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2013.0510"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.31010"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1186\/s13046-022-02574-0"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1038\/s41594-019-0351-6"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2202949"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1186\/s13229-018-0244-2"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci10120951"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/noad155"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2018.05.022"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2020.107526"}],"container-title":["Environmental Science &amp; Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.5c16736","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.5c16736","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T18:23:52Z","timestamp":1773944632000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.est.5c16736"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,12]]},"references-count":63,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,2,24]]}},"alternative-id":["10.1021\/acs.est.5c16736"],"URL":"https:\/\/doi.org\/10.1021\/acs.est.5c16736","relation":{},"ISSN":["0013-936X","1520-5851"],"issn-type":[{"value":"0013-936X","type":"print"},{"value":"1520-5851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,12]]}}}