{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:30:08Z","timestamp":1791390608797,"version":"4.3.3"},"reference-count":73,"publisher":"American Chemical Society (ACS)","issue":"27","license":[{"start":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T00:00:00Z","timestamp":1782691200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T00:00:00Z","timestamp":1782691200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T00:00:00Z","timestamp":1782691200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100016047","name":"Science Fund of the Republic of Serbia","doi-asserted-by":"publisher","award":["7010"],"award-info":[{"award-number":["7010"]}],"id":[{"id":"10.13039\/501100016047","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ. Sci. Technol."],"published-print":{"date-parts":[[2026,7,14]]},"DOI":"10.1021\/acs.est.5c17571","type":"journal-article","created":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T19:43:27Z","timestamp":1782762207000},"page":"19064-19079","source":"Crossref","is-referenced-by-count":2,"title":["Population-Specific Probabilistic Risk Assessment of PFOA for Ovarian Function Using PBTK Translation of Data from Subacute Exposure of Mice"],"prefix":"10.1021","volume":"60","author":[{"given":"Jelena","family":"Vukcevic","sequence":"first","affiliation":[{"name":"University of Novi Sad","place":["Novi Sad, Serbia"]},{"name":"Faculty of Sciences, Department of Biology and Ecology","place":["Novi Sad, Serbia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivana","family":"Ivelja","sequence":"additional","affiliation":[{"name":"University of Novi Sad","place":["Novi Sad, Serbia"]},{"name":"Faculty of Sciences, Department of Biology and Ecology","place":["Novi Sad, Serbia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4460-8555","authenticated-orcid":true,"given":"Livia","family":"Vajda","sequence":"additional","affiliation":[{"name":"University of Novi Sad","place":["Novi Sad, Serbia"]},{"name":"Faculty of Sciences, Department of Biology and Ecology","place":["Novi Sad, Serbia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1519-5643","authenticated-orcid":true,"given":"Nemanja","family":"Todorovic","sequence":"additional","affiliation":[{"name":"University of Novi Sad","place":["Novi Sad, Serbia"]},{"name":"Faculty of Medicine, Department of Pharmacy","place":["Novi Sad, Serbia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8354-3868","authenticated-orcid":true,"given":"Mladena","family":"Lalic-Popovic","sequence":"additional","affiliation":[{"name":"University of Novi Sad","place":["Novi Sad, Serbia"]},{"name":"Faculty of Medicine, Department of Pharmacy","place":["Novi Sad, Serbia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2470-2018","authenticated-orcid":true,"given":"Jelena","family":"Markovic Filipovic","sequence":"additional","affiliation":[{"name":"University of Novi Sad","place":["Novi Sad, Serbia"]},{"name":"Faculty of Sciences, Department of Biology and Ecology","place":["Novi Sad, Serbia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1025-8358","authenticated-orcid":true,"given":"Nebojsa","family":"Andric","sequence":"additional","affiliation":[{"name":"University of Novi Sad","place":["Novi Sad, Serbia"]},{"name":"Faculty of Sciences, Department of Biology and Ecology","place":["Novi Sad, Serbia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,6,29]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1080\/15320383.2018.1562420"},{"key":"ref2\/cit2","unstructured":"EPA,\nU. S. FACT\n                      SHEET PFOA & PFOS Drinking\nWater Health Advisories\n                      , EPA 800-F-16\u2013003, 2016."},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/s41545-023-00274-6"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.yrtph.2021.105025"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2025.120916"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1289\/EHP13152"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1289\/EHP5337"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwp279"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.156323"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2025.1526918"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1289\/ehp15422"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.3390\/toxics12020104"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2020.105686"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2020.109963"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2017-02783"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1289\/EHP1203"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgaa303"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijheh.2025.114568"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2017.09.030"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2023.122698"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1289\/EHP14876"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1111\/jne.12848"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/tox.22661"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2025.108986"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2023.166954"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2022.03.011"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.2903\/j.efsa.2018.5194"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.2903\/j.efsa.2020.6223"},{"key":"ref29\/cit29","unstructured":"ATSDR. PFAs Toxicological Profile Key Messages. 2018. (Accessed July 18, 2025)."},{"key":"ref30\/cit30","unstructured":"EPA U. S.\n                      Human Health Toxicity Assessment for Perfluorooctane Sulfonic\nAcid (PFOS) and Related Salts\n                      ; 815R24007, EPA, 2024. (Accessed 18 July 2025)."},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2025.121947"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2025.139402"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfab039"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2022.113559"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.3390\/toxics12040271"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2019.124755"},{"key":"ref37\/cit37","unstructured":"ATSDR.\n                      Toxicological profile for perfluoroalkyls.\n(Draft for public\ncomment)\n                      , 2009."},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1007\/s00420-007-0213-0"},{"key":"ref39\/cit39","volume-title":"Test no. 407: Repeated dose 28-day Oral toxicity study in rodents","author":"OECD","year":"2008"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2010.00872.x"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0170555"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.acthis.2017.12.001"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2199-7-3"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3317"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1923"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-014-0550-8"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-8-387"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-14-128"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2014.01.007"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1080\/15287394.2012.722523"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.yrtph.2010.12.004"},{"key":"ref52\/cit52","unstructured":"Elcombe, C. R.; Wolf, C. R.; Weswood, A. L. US patent application publication. US 2013\/0029928, 2011. Available from: https:\/\/patentimages.storage.googleapis.com\/24\/ee\/73\/f58267c7d70dde\/WO2011101643A1.pdf."},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.4103\/0976-0105.177703"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfac097"},{"key":"ref55\/cit55","unstructured":"EPA, U.S.\n                      Health Effects Support Document for Perfluorooctane Sulfonate\n(PFOS)\n                      , 822-R-16\u2013002, EPA, 2016."},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kft204"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2025.119089"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.21037\/tcr-24-887"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202201246RR"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-40329-8"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2006.12.002"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80402-X"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.11.021"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1126\/science.287.5451.319"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2020.07.005"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1172\/JCI33835"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1007\/s10661-025-13689-0"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1289\/EHP11885"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-008-0553-z"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-025-03127-5"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.15333"},{"key":"ref72\/cit72","unstructured":"World Health Organization\n                      Obesity and Overweight\n                      , 2022."},{"key":"ref73\/cit73","unstructured":"World\nObesity Federation. World\nObesity Atlas 2025.\n                      World Obesity\nFederation\n                      : London, UK, 2025."}],"container-title":["Environmental Science & Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.5c17571","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.5c17571","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T14:37:49Z","timestamp":1784039869000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.est.5c17571"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,29]]},"references-count":73,"journal-issue":{"issue":"27","published-print":{"date-parts":[[2026,7,14]]}},"alternative-id":["10.1021\/acs.est.5c17571"],"URL":"https:\/\/doi.org\/10.1021\/acs.est.5c17571","relation":{},"ISSN":["0013-936X","1520-5851"],"issn-type":[{"value":"0013-936X","type":"print"},{"value":"1520-5851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,29]]}}}