{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T15:04:41Z","timestamp":1790089481758,"version":"4.0.1"},"reference-count":103,"publisher":"American Chemical Society (ACS)","issue":"37","license":[{"start":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:00:00Z","timestamp":1789084800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci?n y Universidades","doi-asserted-by":"publisher","award":["PID2022-139446OB-C22"],"award-info":[{"award-number":["PID2022-139446OB-C22"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci?n y Universidades","doi-asserted-by":"publisher","award":["RYC2022-038179-I"],"award-info":[{"award-number":["RYC2022-038179-I"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014440","name":"Ministerio de Ciencia, Innovaci?n y Universidades","doi-asserted-by":"publisher","award":["RYC2023-043202-I"],"award-info":[{"award-number":["RYC2023-043202-I"]}],"id":[{"id":"10.13039\/100014440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico","doi-asserted-by":"publisher","award":["150918\/2025-9"],"award-info":[{"award-number":["150918\/2025-9"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004895","name":"European Social Fund Plus","doi-asserted-by":"publisher","award":["RYC2023-043202-I"],"award-info":[{"award-number":["RYC2023-043202-I"]}],"id":[{"id":"10.13039\/501100004895","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,22]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Endocrine-disrupting chemicals (EDCs) are increasingly implicated in chronic diseases, yet their biomonitoring in human studies still relies mainly on urine and serum, which capture only short-term exposure to these fast-elimination compounds. Here, we evaluated hair as a complementary and long-term biomonitoring matrix for EDC mixtures by integrating it into an LC-HRMS exposomics workflow together with paired serum and urine samples. We developed and validated a method targeting 44 endocrine disruptors from five chemical families (benzophenones, phthalates, parabens, bisphenols, and organophosphate esters), combining quantitative analysis with suspect screening and semi-quantification of phase II metabolites. Applied to samples from 20 postmenopausal women, the hair-based approach provided the broadest coverage and highest concentrations (31\/44 compounds), up to about three orders of magnitude higher than in urine or serum, consistent with distinct accumulation mechanisms and temporal integration windows. In hair, EDCs were present in unconjugated form (&amp;gt;99%), whereas urine was dominated by conjugated metabolites and serum showed limited detection. Overall, these findings demonstrate that integrating hair into multimatrix exposomics designs substantially expands both the chemical and temporal resolution of human exposure assessment.<\/jats:p>","DOI":"10.1021\/acs.est.6c05029","type":"journal-article","created":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T16:01:37Z","timestamp":1789142497000},"page":"26100-26115","source":"Crossref","is-referenced-by-count":1,"title":["Exposomic Assessment\nof Endocrine-Disrupting Chemicals\nUsing Hair: A Cross-Matrix Comparison with Serum and Urine by LC-HRMS\nand Metabolite Profiling"],"prefix":"10.1021","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0044-2063","authenticated-orcid":true,"given":"Ana","family":"Gonza\u0301lez-Ruiz","sequence":"first","affiliation":[{"name":"Universitat Rovira i Virgili (URV) , , Sant Llorenc\u0327 21 , ,","place":["Reus, Spain, 43201"]},{"name":"Institut d\u2019Investigacio\u0301 Sanita\u0300ria Pere Virgili (IISPV) , Doctor Mallafre\u0301 Guasch 4 , ,","place":["Tarragona, Spain, 43005"]},{"name":"Institute of Environmental Assessment and Water Research (IDAEA), Spanish Council of Scientific Research (CSIC) , , Jordi Girona 18-26 , ,","place":["Barcelona, Spain, 08034"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5134-1196","authenticated-orcid":true,"given":"Adria\u0300","family":"Sunyer-Caldu\u0301","sequence":"additional","affiliation":[{"name":"Stockholm University , , ,","place":["Stockholm, Sweden, 106 91"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo Braz","family":"Carneiro","sequence":"additional","affiliation":[{"name":"University of Sa\u0303o Paulo (EESC-USP) , , Joa\u0303o Dagnone Ave 1100 , ,","place":["Sa\u0303o Carlos, Brazil, 13563-120"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2246-8279","authenticated-orcid":true,"given":"Esteban","family":"Restrepo-Montes","sequence":"additional","affiliation":[{"name":"Institute of Environmental Assessment and Water Research (IDAEA), Spanish Council of Scientific Research (CSIC) , , Jordi Girona 18-26 , ,","place":["Barcelona, Spain, 08034"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia","family":"Ballester-Miro\u0301","sequence":"additional","affiliation":[{"name":"Institute of Environmental Assessment and Water Research (IDAEA), Spanish Council of Scientific Research (CSIC) , , Jordi Girona 18-26 , ,","place":["Barcelona, Spain, 08034"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Lobato-Berezo","sequence":"additional","affiliation":[{"name":"Hospital Universitari Mu\u0301tua Terrassa , Plac\u0327a Dr. Robert 5 , ,","place":["Terrassa, Spain, 08221"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramo\u0301n M.","family":"Pujol","sequence":"additional","affiliation":[{"name":"Institut Hospital del Mar , Passeig Mari\u0301tim 25-29 , ,","place":["Barcelona, Spain, 08003"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Montse","family":"Marque\u0300s","sequence":"additional","affiliation":[{"name":"Institute of Environmental Assessment and Water Research (IDAEA), Spanish Council of Scientific Research (CSIC) , , Jordi Girona 18-26 , ,","place":["Barcelona, Spain, 08034"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4269-1036","authenticated-orcid":true,"given":"Rube\u0301n","family":"Gil-Solsona","sequence":"additional","affiliation":[{"name":"Institute of Environmental Assessment and Water Research (IDAEA), Spanish Council of Scientific Research (CSIC) , , Jordi Girona 18-26 , ,","place":["Barcelona, Spain, 08034"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5987-0399","authenticated-orcid":true,"given":"Pablo","family":"Gago-Ferrero","sequence":"additional","affiliation":[{"name":"Institute of Environmental Assessment and Water Research (IDAEA), Spanish Council of Scientific Research (CSIC) , , Jordi Girona 18-26 , ,","place":["Barcelona, Spain, 08034"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,9,11]]},"reference":[{"key":"2026092210111292100_cit1","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1126\/science.aay3164","article-title":"The Exposome and\nHealth: Where Chemistry Meets Biology","volume":"367","author":"Vermeulen","year":"2020","journal-title":"Science"},{"issue":"5","key":"2026092210111292100_cit2","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1038\/s41576-022-00569-3","article-title":"Molecular Mechanisms of Environmental\nExposures and Human Disease","volume":"24","author":"Wu","year":"2023","journal-title":"Nat. Rev. Genet."},{"issue":"5","key":"2026092210111292100_cit3","doi-asserted-by":"publisher","first-page":"812","DOI":"10.1038\/s41593-024-01627-1","article-title":"Assessing the Contribution\nof the Chemical Exposome to Neurodegenerative Disease","volume":"27","author":"Lefe\u0300vre-Arbogast","year":"2024","journal-title":"Nat. Neurosci."},{"issue":"1","key":"2026092210111292100_cit4","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1038\/s41574-019-0273-8","article-title":"Consensus\non the Key Characteristics of Endocrine-Disrupting Chemicals as a\nBasis for Hazard Identification","volume":"16","author":"La Merrill","year":"2020","journal-title":"Nat. Rev. Endocrinol."},{"issue":"12","key":"2026092210111292100_cit5","doi-asserted-by":"publisher","first-page":"4984","DOI":"10.1021\/acs.est.2c09390","article-title":"Food Thermal Labels\nAre a Source of Dietary Exposure to Bisphenol\nS and Other Color Developers","volume":"57","author":"Xu","year":"2023","journal-title":"Environ. Sci.\nTechnol."},{"key":"2026092210111292100_cit6","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1016\/j.envres.2018.03.035","article-title":"Medications as a Potential Source of Exposure to Parabens\nin the U.S. Population","volume":"164","author":"Dodge","year":"2018","journal-title":"Environ. Res."},{"key":"2026092210111292100_cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.157873","article-title":"Long-Term Stability\nof Several Endocrine Disruptors in the First Morning Urine Samples\nand Their Associations with Lifestyle Characteristics","volume":"850","author":"Jia","year":"2022","journal-title":"Sci. Total Environ."},{"issue":"8","key":"2026092210111292100_cit8","doi-asserted-by":"publisher","first-page":"3726","DOI":"10.1021\/acs.est.3c09756","article-title":"Exposure to\nMEHP during Pregnancy and Lactation Impairs Offspring Growth and Development\nby Disrupting Thyroid Hormone Homeostasis","volume":"58","author":"Yin","year":"2024","journal-title":"Environ.\nSci. Technol."},{"key":"2026092210111292100_cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2024.108689","article-title":"Paternal Exposures\nto Endocrine-Disrupting Chemicals Induce Intergenerational Epigenetic\nInfluences on Offspring: A Review","volume":"187","author":"Zhang","year":"2024","journal-title":"Environ.\nInt."},{"issue":"18","key":"2026092210111292100_cit10","doi-asserted-by":"publisher","first-page":"7719","DOI":"10.1021\/acs.est.3c07150","article-title":"Serum Phthalate\nConcentrations and Biomarkers of Oxidative Stress in Adipose Tissue\nin a Spanish Adult Cohort","volume":"58","author":"Pe\u0301rez-Di\u0301az","year":"2024","journal-title":"Environ. Sci. Technol."},{"key":"2026092210111292100_cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2023.108176","article-title":"Prenatal Exposures\nto Mixtures of Endocrine Disrupting Chemicals and Sex-Specific Associations\nwith Children\u2019s BMI and Overweight at 5.5 Years of Age in the\nSELMA Study","volume":"179","author":"Svensson","year":"2023","journal-title":"Environ. Int."},{"issue":"8","key":"2026092210111292100_cit12","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.15041","article-title":"Association\nof Exposure\nto Endocrine-Disrupting Chemicals during Adolescence with Attention-Deficit\/Hyperactivity\nDisorder-Related Behaviors","volume":"3","author":"Shoaff","year":"2020","journal-title":"JAMA Network Open"},{"key":"2026092210111292100_cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2023.108271","article-title":"Perinatal Exposure to Potential Endocrine\nDisrupting Chemicals and Autism Spectrum Disorder: From Norwegian\nBirth Cohort to Zebrafish Studies","volume":"181","author":"Desalegn","year":"2023","journal-title":"Environ.\nInt."},{"key":"2026092210111292100_cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2021.103330","article-title":"Exposure\nto Endocrine Disruptors and Risk of Breast Cancer: A Systematic Review","volume":"161","author":"Rocha","year":"2021","journal-title":"Crit. Rev. Oncol. \/Hematol."},{"key":"2026092210111292100_cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2021.112085","article-title":"Impacts of Endocrine-Disrupting Chemicals\non Prostate\nFunction and Cancer","volume":"204","author":"Lacouture","year":"2022","journal-title":"Environ. Res."},{"issue":"17","key":"2026092210111292100_cit16","doi-asserted-by":"publisher","first-page":"4063","DOI":"10.1007\/s00216-014-7748-1","article-title":"Human Biomonitoring\nof Emerging Pollutants through Non-Invasive Matrices: State of the\nArt and Future Potential","volume":"406","author":"Alves","year":"2014","journal-title":"Anal. Bioanal. Chem."},{"key":"2026092210111292100_cit17","doi-asserted-by":"publisher","first-page":"16302","DOI":"10.1021\/acs.est.4c05235","article-title":"Longitudinal Exposomics in a Multiomic\nWellness Cohort Reveals Distinctive and Dynamic Environmental Chemical\nMixtures in Blood","volume":"58","author":"Sdougkou","year":"2024","journal-title":"Environ. Sci. Technol."},{"key":"2026092210111292100_cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2022.107342","article-title":"Investigating Children\u2019s Chemical\nExposome \u2013 Description and Possible Determinants of Exposure\nin the Region of Luxembourg Based on Hair Analysis","volume":"165","author":"Iglesias-Gonza\u0301lez","year":"2022","journal-title":"Environ. Int."},{"key":"2026092210111292100_cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2021.146330","article-title":"Biomonitoring of Fast-Elimination\nEndocrine Disruptors\n\u2013 Results from a 6-Month Follow up on Human Volunteers with\nRepeated Urine and Hair Collection","volume":"778","author":"Fa\u0308ys","year":"2021","journal-title":"Sci. Total\nEnviron."},{"key":"2026092210111292100_cit20","doi-asserted-by":"crossref","unstructured":"Lallmahomed, A.; Mercier, F.; Costet, N.; Slimani, K.; Dao, T. P. T.; Pe\u0301cheux, M.; Bessonneau, V.; David, A.; Bonvallot, N.; Bot, B. L.\n          Hair Biomonitoring\nUnveiled: A New Angle on Organophosphorus Flame-Retardant Exposure\nversus Urine and Blood\n          SSRN Prepr.\n          2026\n          10.2139\/ssrn.6153657.","DOI":"10.2139\/ssrn.6153657"},{"key":"2026092210111292100_cit21","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1016\/j.scitotenv.2019.06.061","article-title":"Hair as a Matrix to Evaluate Cumulative and Aggregate\nExposure to Pesticides in Winegrowers","volume":"687","author":"Polledri","year":"2019","journal-title":"Sci.\nTotal Environ."},{"key":"2026092210111292100_cit22","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/j.envint.2017.10.025","article-title":"Assessment\nof Human Exposure to Pesticides by Hair\nAnalysis: The Case of Vegetable-Producing Areas in Burkina Faso","volume":"111","author":"Lehmann","year":"2018","journal-title":"Environ. Int."},{"key":"2026092210111292100_cit23","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/j.envres.2014.07.012","article-title":"Biomonitoring\nof Dialkylphosphate\nMetabolites (DAPs) in Urine and Hair Samples of Sprayers and Rural\nResidents of Crete, Greece","volume":"134","author":"Kokkinaki","year":"2014","journal-title":"Environ. Res."},{"issue":"1","key":"2026092210111292100_cit24","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.ijheh.2019.10.010","article-title":"Multiple Pesticides in Mothers\u2019\nHair Samples and Children\u2019s Measurements at Birth: Results\nfrom the French National Birth Cohort (ELFE)","volume":"223","author":"Be\u0301ranger","year":"2020","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"2026092210111292100_cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2019.105332","article-title":"Cumulative Exposure to Organic Pollutants\nof French Children Assessed by Hair Analysis","volume":"134","author":"Iglesias-Gonza\u0301lez","year":"2020","journal-title":"Environ. Int."},{"key":"2026092210111292100_cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2021.106481","article-title":"Hair\nversus Urine for the Biomonitoring of Pesticide Exposure: Results\nfrom a Pilot Cohort Study on Pregnant Women","volume":"152","author":"Hardy","year":"2021","journal-title":"Environ. Int."},{"key":"2026092210111292100_cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2021.106526","article-title":"Population-Based\nBiomonitoring of Exposure to Persistent and Non-Persistent Organic\nPollutants in the Grand Duchy of Luxembourg: Results from Hair Analysis","volume":"153","author":"Peng","year":"2021","journal-title":"Environ. Int."},{"key":"2026092210111292100_cit28","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1016\/j.chemosphere.2014.10.044","article-title":"Biomonitoring\nof Bisphenol A in Hair\nof Greek Population","volume":"118","author":"Tzatzarakis","year":"2015","journal-title":"Chemosphere"},{"key":"2026092210111292100_cit29","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.936738","article-title":"Hair Sample\nAnalysis of Residents from Olsztyn, Northeastern Poland, to Evaluate\nLevels of Bisphenol S and Bisphenol A: A Pilot Study","volume":"28","author":"Gonkowski","year":"2022","journal-title":"Med. Sci. Monit."},{"key":"2026092210111292100_cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2019.133864","article-title":"Exposure Assessment\nto Parabens, Bisphenol A and Perfluoroalkyl Compounds in Children,\nWomen and Men by Hair Analysis","volume":"695","author":"Marti\u0301n","year":"2019","journal-title":"Sci. Total Environ."},{"key":"2026092210111292100_cit31","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.cca.2012.10.009","article-title":"Determination\nof Di-(2-Ethylhexyl)Phthalate\n(DEHP) Metabolites in Human Hair Using Liquid Chromatography-Tandem\nMass Spectrometry","volume":"420","author":"Chang","year":"2013","journal-title":"Clin. Chim. Acta"},{"key":"2026092210111292100_cit32","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.envpol.2018.02.040","article-title":"Organophosphate\nEsters and Phthalate Esters in Human Hair from Rural and Urban Areas,\nChongqing, China: Concentrations, Composition Profiles and Sources\nin Comparison to Street Dust","volume":"237","author":"He","year":"2018","journal-title":"Environ. Pollut."},{"issue":"5","key":"2026092210111292100_cit33","doi-asserted-by":"publisher","first-page":"2820","DOI":"10.1021\/acs.est.8b05503","article-title":"Legacy and Currently\nUsed Organic Contaminants in Human Hair and Hand Wipes of Female E-Waste\nDismantling Workers and Workplace Dust in South China","volume":"53","author":"Qiao","year":"2019","journal-title":"Environ. Sci. Technol."},{"issue":"26","key":"2026092210111292100_cit34","doi-asserted-by":"publisher","first-page":"6665","DOI":"10.1007\/s00216-014-8106-z","article-title":"Development\nof a Broad Spectrum Method for Measuring Flame Retardants - Overcoming\nthe Challenges of Non-Invasive Human Biomonitoring Studies","volume":"406","author":"Kucharska","year":"2014","journal-title":"Anal. Bioanal. Chem."},{"key":"2026092210111292100_cit35","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1016\/j.chemosphere.2016.11.008","article-title":"Biomonitoring of 21 Endocrine Disrupting Chemicals\nin Human Hair Samples Using Ultra-High Performance Liquid Chromatography\u2013Tandem\nMass Spectrometry","volume":"168","author":"Rodri\u0301guez-Go\u0301mez","year":"2017","journal-title":"Chemosphere"},{"issue":"1","key":"2026092210111292100_cit36","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1002\/rcm.8302","article-title":"Development of a\nLiquid Chromatography\/Tandem Mass\nSpectrometry Method for Monitoring of Long-Term Exposure to Parabens","volume":"33","author":"Cho","year":"2019","journal-title":"Rapid Commun. Mass Spectrom."},{"issue":"29","key":"2026092210111292100_cit37","doi-asserted-by":"publisher","first-page":"8725","DOI":"10.1007\/s00216-015-9026-2","article-title":"Multi-Class\nMethod for Biomonitoring of Hair Samples Using Gas Chromatography-Mass\nSpectrometry","volume":"407","author":"Marti\u0301n","year":"2015","journal-title":"Anal. Bioanal. Chem."},{"key":"2026092210111292100_cit38","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.aca.2016.10.004","article-title":"Analytical Method for\nBiomonitoring of Endocrine-Disrupting Compounds (Bisphenol A, Parabens,\nPerfluoroalkyl Compounds and a Brominated Flame Retardant) in Human\nHair by Liquid Chromatography-Tandem Mass Spectrometry","volume":"945","author":"Marti\u0301n","year":"2016","journal-title":"Anal. Chim. Acta"},{"key":"2026092210111292100_cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.156789","article-title":"Associations between Concentrations of Typical Ultraviolet\nFilter\nBenzophenones in Indoor Dust and Human Hair from China: A Human Exposure\nStudy","volume":"841","author":"Li","year":"2022","journal-title":"Sci. Total Environ."},{"key":"2026092210111292100_cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2020.116394","article-title":"Plasticizer\nContamination in the Urine and Hair of Preschool Children, Airborne\nParticles in Kindergartens, and Drinking Water in Hong Kong","volume":"271","author":"Li","year":"2021","journal-title":"Environ. Pollut."},{"key":"2026092210111292100_cit41","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.envint.2015.05.015","article-title":"Assessment of Human Hair as an Indicator\nof Exposure\nto Organophosphate Flame Retardants. Case Study on a Norwegian Mother-Child\nCohort","volume":"83","author":"Kucharska","year":"2015","journal-title":"Environ. Int."},{"key":"2026092210111292100_cit42","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1016\/j.cca.2021.10.004","article-title":"Analysis of Hair Steroid\nHormone Concentrations at Different Parts of the Head by Liquid Chromatography-Tandem\nMass Spectrometry","volume":"523","author":"Hobo","year":"2021","journal-title":"Clin. Chim. Acta"},{"key":"2026092210111292100_cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.heha.2023.100086","article-title":"Applying Hair Exposome\nfor Linking\nEnvironmental Exposure to Reproductive Health: A Comprehensive Review\nand Research Perspective","volume":"9","author":"Ren","year":"2024","journal-title":"Hyg. Environ. Health\nAdv."},{"issue":"3","key":"2026092210111292100_cit44","doi-asserted-by":"publisher","DOI":"10.20517\/jeea.2024.17","article-title":"Establishing\na Biomonitoring Baseline by Characterizing the Hair Metabolome across\nAge and Sex Using High-Resolution Mass Spectrometry","volume":"3","author":"Chang","year":"2024","journal-title":"J. Environ. Exposure Assess."},{"key":"2026092210111292100_cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2020.127807","article-title":"Analysis of Polybrominated\nDiphenyl Ethers, Hexabromocyclododecanes, and Legacy and Emerging\nPhosphorus Flame Retardants in Human Hair","volume":"262","author":"Tang","year":"2021","journal-title":"Chemosphere"},{"key":"2026092210111292100_cit46","unstructured":"ECHA, E. C. A.\n          . ECHA\nCHEM Database2025https:\/\/chem.echa.europa.eu\/. (accessed February 25, 2026)."},{"key":"2026092210111292100_cit47","unstructured":"European Commission.\n          . 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