{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:01:01Z","timestamp":1791295261462,"version":"4.1.0"},"reference-count":58,"publisher":"American Chemical Society (ACS)","issue":"39","license":[{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["42571083"],"award-info":[{"award-number":["42571083"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Key Research and Development Plan of China","award":["2021YFC3200600"],"award-info":[{"award-number":["2021YFC3200600"]}]},{"name":"Shanghai Chengtou Water Group Co. Ltd. Scientific Research Reserve Project","award":["KY.ZH.24.008"],"award-info":[{"award-number":["KY.ZH.24.008"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The dissemination of antibiotic resistance genes (ARGs) in sewer systems poses a potential threat to public health. However, it is currently unclear how hydrogen sulfide (H2S) in anaerobic sewers affects plasmid-mediated ARG transfer. Here, we evaluated the effects of environmentally relevant concentrations (1\u2013100 \u03bcmol\u00b7L\u20131) of H2S on ARG transfer across different sewer microbial communities. The results demonstrated that H2S significantly enhanced the transfer frequency of plasmid pKJK5 in sediment-derived (2.06\u20133.06-fold), sewage-derived (1.50\u20132.81-fold), and bioaerosol-derived (2.42\u20134.68-fold) recipient communities in standardized liquid anaerobic conjugation assays. In mixed-community models, H2S increased total acyl-homoserine lactone (AHL)-equivalent signals and was associated with selective enrichment of polysaccharides in extracellular polymeric substances (EPS), coinciding with enhanced microbial aggregation and contact. In single-strain models, H2S was associated with reductive-stress-like responses, lowered the NAD+\/NADH ratio, enhanced phosphofructokinase and glyceraldehyde-3-phosphate dehydrogenase activities, strengthened proton motive force, and increased ATP content. Inhibitor experiments and structural equation modeling suggested ATP availability as the strongest intracellular predictor of enhanced transfer, with AHL-associated EPS changes acting as a potential extracellular contributor. These findings identify a concentration-dependent sulfide effect on conjugation under anaerobic conditions and support a testable pathway-level framework for future in situ sewer studies.<\/jats:p>","DOI":"10.1021\/acs.est.6c07553","type":"journal-article","created":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T15:02:41Z","timestamp":1790175761000},"page":"28040-28051","source":"Crossref","is-referenced-by-count":0,"title":["Trace Hydrogen Sulfide\nEnhances Plasmid-Mediated Antibiotic\nResistance Gene Transfer under Anaerobic Sewer-Like Conditions: Associations\nwith Contact and Energy-State Responses"],"prefix":"10.1021","volume":"60","author":[{"given":"Jun","family":"Hong","sequence":"first","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiqi","family":"Hou","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]},{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junnan","family":"Li","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuhui","family":"Huang","sequence":"additional","affiliation":[{"name":"Fudan University , , ,","place":["Shanghai, China, 200433"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shanghai Municipal Water Resources Development and Utilization National Engineering Center Co., Ltd. , ,","place":["Shanghai, China, 200082"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2091-6123","authenticated-orcid":true,"given":"Peng","family":"Li","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7672-5727","authenticated-orcid":true,"given":"Yiliang","family":"He","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]},{"name":"Shanghai Jiao Tong University , , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,9,23]]},"reference":[{"issue":"16","key":"2026100609063981900_cit1","doi-asserted-by":"publisher","first-page":"10012","DOI":"10.1021\/acs.est.0c01870","article-title":"CeO2 Nanoparticles Regulate the Propagation\nof Antibiotic Resistance Genes by Altering Cellular Contact and Plasmid\nTransfer","volume":"54","author":"Yu","year":"2020","journal-title":"Environ. Sci. Technol."},{"key":"2026100609063981900_cit2","doi-asserted-by":"publisher","first-page":"118853","DOI":"10.1016\/j.watres.2022.118853","article-title":"Non-point\nsource fecal contamination from aging wastewater infrastructure is\na primary driver of antibiotic resistance in surface waters","volume":"222","author":"Damashek","year":"2022","journal-title":"Water Res."},{"key":"2026100609063981900_cit3","doi-asserted-by":"publisher","first-page":"128634","DOI":"10.1016\/j.jhazmat.2022.128634","article-title":"Trace antibiotics increase\nthe risk of antibiotic resistance genes transmission by regulating\nthe biofilm extracellular polymeric substances and microbial community\nin the sewer","volume":"432","author":"Xin","year":"2022","journal-title":"J. Hazard. Mater."},{"issue":"1","key":"2026100609063981900_cit4","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1038\/ismej.2016.90","article-title":"Phages rarely encode\nantibiotic resistance genes: a\ncautionary tale for virome analyses","volume":"11","author":"Enault","year":"2017","journal-title":"ISME J."},{"key":"2026100609063981900_cit5","doi-asserted-by":"publisher","first-page":"140147","DOI":"10.1016\/j.jhazmat.2025.140147","article-title":"Bacterial hosts, distribution\npatterns, and risk burden of antibiotic\nresistance genes in urban sewers: From the perspective of horizontal\nand vertical chains","volume":"499","author":"Hong","year":"2025","journal-title":"J. Hazard. Mater."},{"key":"2026100609063981900_cit6","doi-asserted-by":"publisher","first-page":"120046","DOI":"10.1016\/j.watres.2023.120046","article-title":"Hydrogen sulfide control\nin sewer systems: A critical review of recent progress","volume":"240","author":"Zhang","year":"2023","journal-title":"Water Res."},{"key":"2026100609063981900_cit7","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1016\/j.watres.2019.03.074","article-title":"Periodic deprivation\nof gaseous hydrogen sulfide affects the activity of the concrete corrosion\nlayer in sewers","volume":"157","author":"Sun","year":"2019","journal-title":"Water Res."},{"key":"2026100609063981900_cit8","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/j.watres.2016.05.036","article-title":"Indirect sulfur\nreduction via polysulfide\ncontributes to serious odor problem in a sewer receiving nitrate dosage","volume":"100","author":"Liang","year":"2016","journal-title":"Water Res."},{"key":"2026100609063981900_cit9","doi-asserted-by":"publisher","first-page":"120403","DOI":"10.1016\/j.watres.2023.120403","article-title":"Antibiotic\nresistome associated with inhalable bioaerosols from wastewater to\natmosphere: Mobility, bacterial hosts, source contributions and resistome\nrisk","volume":"243","author":"Yang","year":"2023","journal-title":"Water Res."},{"key":"2026100609063981900_cit10","doi-asserted-by":"publisher","first-page":"121572","DOI":"10.1016\/j.watres.2024.121572","article-title":"Spread\nof antibiotic resistance genes in drinking water reservoirs:\nInsights from a deep metagenomic study using a curated database","volume":"256","author":"Wang","year":"2024","journal-title":"Water Res."},{"issue":"9","key":"2026100609063981900_cit11","doi-asserted-by":"publisher","first-page":"2113","DOI":"10.1021\/acssynbio.9b00210","article-title":"Synthetic Gene Circuits Enable Escherichia\ncoli To Use Endogenous H2S as a Signaling Molecule for\nQuorum Sensing","volume":"8","author":"Liu","year":"2019","journal-title":"ACS Synth. Biol."},{"key":"2026100609063981900_cit12","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.jes.2019.06.011","article-title":"Town-scale microbial\nsewer community\nand H2S emissions response to common chemical and biological\ndosing treatments","volume":"87","author":"Mathews","year":"2020","journal-title":"J. Environ. Sci."},{"key":"2026100609063981900_cit13","doi-asserted-by":"publisher","first-page":"121739","DOI":"10.1016\/j.watres.2024.121739","article-title":"Impact of hydrogen\nsulfide on anammox and nitrate\/nitrite-dependent anaerobic methane\noxidation coupled technologies","volume":"257","author":"Chen","year":"2024","journal-title":"Water Res."},{"key":"2026100609063981900_cit14","doi-asserted-by":"publisher","first-page":"131157","DOI":"10.1016\/j.jhazmat.2023.131157","article-title":"Sulfide inhibition\non polyphosphate accumulating organisms and glycogen accumulating\norganisms: Cumulative inhibitory effect and recoverability","volume":"451","author":"Meng","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"2026100609063981900_cit15","doi-asserted-by":"publisher","first-page":"121222","DOI":"10.1016\/j.watres.2024.121222","article-title":"Regulation\nof quorum sensing for the manipulation of conjugative transfer of\nantibiotic resistance genes in wastewater treatment system","volume":"253","author":"Qiu","year":"2024","journal-title":"Water Res."},{"key":"2026100609063981900_cit16","doi-asserted-by":"publisher","first-page":"101225","DOI":"10.1016\/j.dwt.2025.101225","article-title":"Influence of wastewater quality on\nthe concentration of hydrogen sulphide in a lab-scale model of pressure\nsanitary sewer system","volume":"322","author":"Boguslawski","year":"2025","journal-title":"Desalin. Water Treat."},{"issue":"7","key":"2026100609063981900_cit17","doi-asserted-by":"publisher","first-page":"4967","DOI":"10.1039\/C7SC00873B","article-title":"\u201cOn\ndemand\u201d redox buffering by H2S contributes to antibiotic\nresistance revealed by a bacteria-specific H2S donor","volume":"8","author":"Shukla","year":"2017","journal-title":"Chem. Sci."},{"key":"2026100609063981900_cit18","doi-asserted-by":"publisher","first-page":"17651","DOI":"10.1021\/jacs.2c07225","article-title":"Subcellular Delivery\nof Hydrogen Sulfide Using Small\nMolecule Donors Impacts Organelle Stress","volume":"144","author":"Gilbert","year":"2022","journal-title":"J.\nAm. Chem. Soc."},{"issue":"5","key":"2026100609063981900_cit19","doi-asserted-by":"publisher","first-page":"2138","DOI":"10.1021\/acs.est.2c08577","article-title":"Applying Dynamic\nMagnetic Field To Promote Anaerobic\nDigestion via Enhancing the Electron Transfer of a Microbial Respiration\nChain","volume":"57","author":"Yang","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"2026100609063981900_cit20","doi-asserted-by":"publisher","first-page":"122292","DOI":"10.1016\/j.envpol.2023.122292","article-title":"Citric acid\nand hydrogen sulfide cooperate to mitigate chromium stress in tomato\nplants by modulating the ascorbate-glutathione cycle, chromium sequestration,\nand subcellular allocation of chromium","volume":"335","author":"Kaya","year":"2023","journal-title":"Environ.\nPollut."},{"key":"2026100609063981900_cit21","doi-asserted-by":"publisher","first-page":"101772","DOI":"10.1016\/j.redox.2020.101772","article-title":"Effects of\nhydrogen sulfide on mitochondrial\nfunction and cellular bioenergetics","volume":"38","author":"Paul","year":"2021","journal-title":"Redox Biol."},{"issue":"8","key":"2026100609063981900_cit22","doi-asserted-by":"publisher","first-page":"1601","DOI":"10.1038\/s42255-024-01068-x","article-title":"Hydrogen\nsulfide produced by the gut microbiota impairs\nhost metabolism via reducing GLP-1 levels in male mice","volume":"6","author":"Qi","year":"2024","journal-title":"Nat. Metab."},{"issue":"11","key":"2026100609063981900_cit23","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1038\/s44221-025-00523-7","article-title":"Hydrogen sulfide drives\nhorizontal transfer of plasmid-borne antibiotic\nresistance genes in wastewater ecosystems","volume":"3","author":"Huang","year":"2025","journal-title":"Nat.\nWater"},{"key":"2026100609063981900_cit24","doi-asserted-by":"publisher","first-page":"133191","DOI":"10.1016\/j.biortech.2025.133191","article-title":"Indole-3-acetic\nacid-mediated root exudates as potential inhibitors of antibiotic\nresistance genes in the rhizosphere microbiome: Mechanistic insights\ninto microbial community assembly and resistome dissemination","volume":"438","author":"Chen","year":"2025","journal-title":"Bioresour. Technol."},{"issue":"17","key":"2026100609063981900_cit25","doi-asserted-by":"publisher","first-page":"6876","DOI":"10.1021\/acs.est.2c09491","article-title":"Phthalates\nPromote\nDissemination of Antibiotic Resistance Genes: An Overlooked Environmental\nRisk","volume":"57","author":"Wu","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"2026100609063981900_cit26","doi-asserted-by":"publisher","first-page":"134255","DOI":"10.1016\/j.jhazmat.2024.134255","article-title":"The fate of\npharmaceuticals and personal care products\n(PPCPs) in sewer sediments: Adsorption triggering resistance gene\nproliferation","volume":"471","author":"Liu","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"2026100609063981900_cit27","doi-asserted-by":"publisher","first-page":"121179","DOI":"10.1016\/j.watres.2024.121179","article-title":"Metabolic\nresponse of bacterial community to sodium hypochlorite and ammonia\nnitrogen affected the antibiotic resistance genes in pipelines biofilm","volume":"252","author":"Wang","year":"2024","journal-title":"Water Res."},{"issue":"4","key":"2026100609063981900_cit28","doi-asserted-by":"publisher","first-page":"1995","DOI":"10.1021\/es203933h","article-title":"Monitoring Bacterial Twitter: Does Quorum Sensing Determine\nthe Behavior of Water and Wastewater Treatment Biofilms?","volume":"46","author":"Shrout","year":"2012","journal-title":"Environ. Sci. Technol."},{"key":"2026100609063981900_cit29","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1016\/j.watres.2017.08.009","article-title":"The role of\nsulfate in aerobic granular sludge process for emerging sulfate-laden\nwastewater treatment","volume":"124","author":"Xue","year":"2017","journal-title":"Water Res."},{"key":"2026100609063981900_cit30","doi-asserted-by":"publisher","first-page":"135181","DOI":"10.1016\/j.jhazmat.2024.135181","article-title":"Mechanisms of conjugative transfer\nof antibiotic resistance genes induced by extracellular polymeric\nsubstances: Insights into molecular diversities and electron transfer\nproperties","volume":"476","author":"Wang","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"2026100609063981900_cit31","doi-asserted-by":"publisher","first-page":"124428","DOI":"10.1016\/j.jhazmat.2020.124428","article-title":"Quantifying\nthe occurrence and transformation potential of extracellular polymeric\nsubstances (EPS)-associated antibiotic resistance genes in activated\nsludge","volume":"408","author":"Wang","year":"2021","journal-title":"J. Hazard. Mater."},{"issue":"42","key":"2026100609063981900_cit32","doi-asserted-by":"publisher","first-page":"22887","DOI":"10.1021\/acs.est.5c10244","article-title":"Unveiling Chemical-Microbial\nCascade Risk Factors from Plastic Pipe Leaching in Drinking Water","volume":"59","author":"Fan","year":"2025","journal-title":"Environ. Sci. Technol."},{"issue":"17","key":"2026100609063981900_cit33","doi-asserted-by":"publisher","first-page":"12573","DOI":"10.1021\/acs.est.2c02701","article-title":"Biochar Effectively\nInhibits the Horizontal Transfer of Antibiotic\nResistance Genes via Restraining the Energy Supply for Conjugative\nPlasmid Transfer","volume":"56","author":"Wu","year":"2022","journal-title":"Environ. Sci. Technol."},{"issue":"14","key":"2026100609063981900_cit34","doi-asserted-by":"publisher","first-page":"8731","DOI":"10.1021\/acs.est.5b01129","article-title":"Ionic Liquid Facilitates the Conjugative\nTransfer of Antibiotic Resistance Genes Mediated by Plasmid RP4","volume":"49","author":"Wang","year":"2015","journal-title":"Environ. Sci. Technol."},{"key":"2026100609063981900_cit35","doi-asserted-by":"publisher","first-page":"15594","DOI":"10.1021\/acs.est.2c04276","article-title":"Reductive\nStress Boosts the Horizontal Transfer of Plasmid-Borne Antibiotic\nResistance Genes: The Neglected Side of the Intracellular Redox Spectrum","volume":"56","author":"Huang","year":"2022","journal-title":"Environ. Sci. Technol."},{"issue":"7","key":"2026100609063981900_cit36","doi-asserted-by":"publisher","first-page":"4124","DOI":"10.1021\/acs.chemrev.3c00683","article-title":"Activity-Based Fluorescent Probes for Hydrogen Sulfide\nand Related Reactive Sulfur Species","volume":"124","author":"Fosnacht","year":"2024","journal-title":"Chem. Rev."},{"issue":"6282","key":"2026100609063981900_cit37","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1126\/science.aad4017","article-title":"Complementation of mitochondrial electron transport\nchain by manipulation of the NAD+\/NADH ratio","volume":"352","author":"Titov","year":"2016","journal-title":"Science"},{"key":"2026100609063981900_cit38","doi-asserted-by":"publisher","first-page":"128473","DOI":"10.1016\/j.jhazmat.2022.128473","article-title":"Enhancing\nthe resistance to H2S toxicity during anaerobic digestion\nof low-strength wastewater through granular activated carbon (GAC)\naddition","volume":"430","author":"Zhang","year":"2022","journal-title":"J. Hazard. Mater."},{"issue":"4","key":"2026100609063981900_cit39","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1007\/s12275-018-7537-1","article-title":"Hydrogen sulfide\ninhibits the growth of Escherichia coli through oxidative damage","volume":"56","author":"Fu","year":"2018","journal-title":"J. Microbiol."},{"issue":"1","key":"2026100609063981900_cit40","doi-asserted-by":"publisher","first-page":"5410","DOI":"10.1038\/s41467-025-61227-w","article-title":"Engineering of ATP\nsynthase for enhancement of proton-to-ATP ratio","volume":"16","author":"Ueno","year":"2025","journal-title":"Nat. Commun."},{"issue":"1","key":"2026100609063981900_cit41","doi-asserted-by":"publisher","first-page":"2173","DOI":"10.1038\/s41467-023-37957-0","article-title":"Dynamic fluctuations\nin a bacterial metabolic network","volume":"14","author":"Bi","year":"2023","journal-title":"Nat. Commun."},{"issue":"23","key":"2026100609063981900_cit42","doi-asserted-by":"publisher","first-page":"14984","DOI":"10.1021\/acs.est.0c03714","article-title":"Impact\nof Redox Conditions on Antibiotic Resistance Conjugative Gene Transfer\nFrequency and Plasmid Fate in Wastewater Ecosystems","volume":"54","author":"Jong","year":"2020","journal-title":"Environ. Sci. Technol."},{"key":"2026100609063981900_cit43","doi-asserted-by":"publisher","first-page":"3917","DOI":"10.1021\/acs.est.2c09631","article-title":"hysiological Responses of Methanosarcina\nbarkeri under Ammonia Stress\nat the Molecular Level: The Unignorable Lipid Reprogramming","volume":"57","author":"Liu","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"2026100609063981900_cit44","doi-asserted-by":"publisher","first-page":"3202","DOI":"10.1038\/s41564-025-02175-5","article-title":"Metabolic control of porin permeability influences\nantibiotic resistance in Escherichia coli","volume":"10","author":"Mun\u0303iz","year":"2025","journal-title":"Nat.\nMicrobiol."},{"issue":"1","key":"2026100609063981900_cit45","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1021\/acs.est.4c10991","article-title":"Microplastics Exacerbated Conjugative\nTransfer of Antibiotic Resistance\nGenes during Ultraviolet Disinfection: Highlighting Difference between\nConventional and Biodegradable Ones","volume":"59","author":"Zhang","year":"2025","journal-title":"Environ.\nSci. Technol."},{"issue":"1","key":"2026100609063981900_cit46","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1007\/s00284-024-03985-2","article-title":"Resensitization of Multi Drug-Resistant\nAeromonas caviae with Exogenous Hydrogen Sulfide Potentiated Antibiotics","volume":"82","author":"Selvakumar","year":"2025","journal-title":"Curr. Microbiol."},{"key":"2026100609063981900_cit47","doi-asserted-by":"publisher","first-page":"122958","DOI":"10.1016\/j.watres.2024.122958","article-title":"A feasible regulation\nstrategy for\nconjugation of antibiotic resistance genes based on different bacterial\nquorum sensing inhibition methods","volume":"272","author":"Jiang","year":"2025","journal-title":"Water Res."},{"issue":"1","key":"2026100609063981900_cit48","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1038\/s41467-023-35978-3","article-title":"Real-time visualisation of the intracellular dynamics\nof conjugative plasmid transfer","volume":"14","author":"Couturier","year":"2023","journal-title":"Nat. Commun."},{"issue":"3","key":"2026100609063981900_cit49","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1111\/mmi.14670","article-title":"Type IV secretion\nsystems: Advances in structure, function,\nand activation","volume":"115","author":"Costa","year":"2021","journal-title":"Mol. Microbiol."},{"key":"2026100609063981900_cit50","doi-asserted-by":"publisher","first-page":"132085","DOI":"10.1016\/j.jhazmat.2023.132085","article-title":"Microplastic biofilm:\nAn important microniche that may accelerate the spread of antibiotic\nresistance genes via natural transformation","volume":"459","author":"Wang","year":"2023","journal-title":"J. Hazard. Mater."},{"issue":"2","key":"2026100609063981900_cit51","doi-asserted-by":"publisher","DOI":"10.1128\/jb.00430-23","article-title":"The atypical organization\nof the luxI\/R family genes in AHL-driven\nquorum-sensing circuits","volume":"206","author":"Cai","year":"2024","journal-title":"J. Bacteriol."},{"issue":"31","key":"2026100609063981900_cit52","doi-asserted-by":"publisher","first-page":"11430","DOI":"10.1021\/acs.est.3c01980","article-title":"Seasonality Determines the Variations\nof Biofilm Microbiome and Antibiotic Resistome in a Pilot-Scale Chlorinated\nDrinking Water Distribution System Deciphered by Metagenome Assembly","volume":"57","author":"Ke","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"2026100609063981900_cit53","doi-asserted-by":"publisher","first-page":"123136","DOI":"10.1016\/j.watres.2025.123136","article-title":"Biofilms on\npipelines shape the microbiome\nand antibiotic resistome in drinking water","volume":"274","author":"Lin","year":"2025","journal-title":"Water Res."},{"issue":"17","key":"2026100609063981900_cit54","doi-asserted-by":"publisher","first-page":"7291","DOI":"10.1021\/acs.est.4c02751","article-title":"Phthalates\nBoost Natural Transformation of Extracellular Antibiotic Resistance\nGenes through Enhancing Bacterial Motility and DNA Environmental Persistence","volume":"58","author":"Wu","year":"2024","journal-title":"Environ. Sci. 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Technol."},{"issue":"10","key":"2026100609063981900_cit57","doi-asserted-by":"publisher","first-page":"6466","DOI":"10.1021\/acs.est.2c01889","article-title":"Nitric\nOxide: A Neglected Driver for the Conjugative Transfer of Antibiotic\nResistance Genes among Wastewater Microbiota","volume":"56","author":"Huang","year":"2022","journal-title":"Environ. Sci. 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