{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T12:44:25Z","timestamp":1791463465390,"version":"4.3.4"},"reference-count":46,"publisher":"American Chemical Society (ACS)","issue":"2","license":[{"start":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T00:00:00Z","timestamp":1574035200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T00:00:00Z","timestamp":1574035200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T00:00:00Z","timestamp":1574035200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["S2016G6417"],"award-info":[{"award-number":["S2016G6417"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["201677003"],"award-info":[{"award-number":["201677003"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["41821005"],"award-info":[{"award-number":["41821005"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Henry Fok Education Foundation","award":["161073"],"award-info":[{"award-number":["161073"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ. Sci. Technol."],"published-print":{"date-parts":[[2020,1,21]]},"DOI":"10.1021\/acs.est.9b03991","type":"journal-article","created":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T10:24:17Z","timestamp":1574072657000},"page":"938-946","source":"Crossref","is-referenced-by-count":72,"title":["Physiologically Based Pharmacokinetic Modeling for Chlorinated Paraffins in Rats and Humans: Importance of Biliary Excretion"],"prefix":"10.1021","volume":"54","author":[{"given":"Zhaomin","family":"Dong","sequence":"first","affiliation":[{"name":"Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China"},{"name":"Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, Beihang University, Beijing 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tong","family":"Li","sequence":"additional","affiliation":[{"name":"Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1312-6254","authenticated-orcid":true,"given":"Yi","family":"Wan","sequence":"additional","affiliation":[{"name":"Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yibin","family":"Sun","sequence":"additional","affiliation":[{"name":"Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1965-7494","authenticated-orcid":true,"given":"Jianying","family":"Hu","sequence":"additional","affiliation":[{"name":"Laboratory for Earth Surface Processes, College of Urban and Environmental Sciences, Peking University, Beijing 100871, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2019,11,18]]},"reference":[{"key":"ref1\/cit1","unstructured":"European Chemicals Bureau,  Alkanes, C10-13, Chloro;\nEuropean Union Risk Assessment Report 2008; 2008; Vol. 81."},{"key":"ref2\/cit2","unstructured":"Environment Canada,  Chlorinated Paraffins. Follow-up\nReport on a PSL1 Assessment for Which Data Were Insufficient to Conclude\nwhether the Substances Were \u201ctoxic\u201d to the Environment\nand to the Human Health; Environment Canada: Ottawa, 2008."},{"key":"ref3\/cit3","volume-title":"The Handbook of Environmental Chemistry","volume":"10","author":"De Boer J.","year":"2010"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.7b06459"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2016.08.105"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2006.05.009"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/es990107q"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/es302463h"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/es703184s"},{"key":"ref10\/cit10","volume-title":"Case Study on Toxiclogical Interactions of Chlorinated Paraffins (UNEP\/POPS\/POPRC.7\/INF\/15)","author":"UNEP (United Nations Environment Programme)","year":"2011"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-009-0489-9"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2005.04.006"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.6b05149"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.6b04246"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.8b02839"},{"key":"ref16\/cit16","volume-title":"Proposal on Next Steps for Short-Chained Chlorinated Paraffins UNEP\/POPS\/POPRC.8\/16\/Annex IV","author":"UNEP","year":"2012"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2016.04.037"},{"key":"ref18\/cit18","volume-title":"Standard Review Risk Assessment of Medium-chain and Lo-ng-chain Chlorinated Paraffins Submitted as PMNs by Dover Chemical","author":"U.S. EPA","year":"2015"},{"key":"ref19\/cit19","volume-title":"Environmental Risk Assessment: Long Chain Chlorinated Paraffins","author":"Brooke D. N.","year":"2009"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/etc.5620220104"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.8805"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1289\/EHP3096"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1289\/EHP2739"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2015.11.066"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.7b04657"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2009.10.019"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfn057"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2015.11.017"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfi288"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.6b01178"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1700558114"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.etap.2010.08.004"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1038\/npjbiofilms.2016.3"},{"key":"ref34\/cit34","volume-title":"Haschek and Rousseaux\u2019s Handbook of Toxicologic Pathology","author":"Haschek W. M.","year":"2013","edition":"3"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1007\/BF00310853"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.yrtph.2010.12.004"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.3390\/ijms12117469"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfw014"},{"key":"ref39\/cit39","volume-title":"Provisional Health Advisories for Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonate (PFOS)","author":"U.S. EPA (U.S. Environmental Protection Agency)","year":"2009"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.11781"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2010.02.008"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1517\/17425255.2012.682569"},{"key":"ref43\/cit43","volume-title":"Chemical-Specific Adjustment Factors for Interspecies Differences and Human Variability: Guidance Document for use of Data in Dose\/Concentration\u2013Response Assessment","author":"WHO (World Health Organization)","year":"2005"},{"key":"ref44\/cit44","volume-title":"Recommended Use of Body Weight 3\/4 as the Default Method in Derivation of the Oral Reference Dose; EPA\/100\/R11\/0001","author":"U.S. EPA","year":"2014"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2017.05.006"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.1002211"}],"container-title":["Environmental Science &amp; Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.est.9b03991","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T23:23:55Z","timestamp":1681773835000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.est.9b03991"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,18]]},"references-count":46,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,1,21]]}},"alternative-id":["10.1021\/acs.est.9b03991"],"URL":"https:\/\/doi.org\/10.1021\/acs.est.9b03991","relation":{},"ISSN":["0013-936X","1520-5851"],"issn-type":[{"value":"0013-936X","type":"print"},{"value":"1520-5851","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,18]]}}}