{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T03:19:04Z","timestamp":1790479144502,"version":"4.1.0"},"reference-count":58,"publisher":"American Chemical Society (ACS)","issue":"10","license":[{"start":{"date-parts":[[2021,2,23]],"date-time":"2021-02-23T00:00:00Z","timestamp":1614038400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,2,23]],"date-time":"2021-02-23T00:00:00Z","timestamp":1614038400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,2,23]],"date-time":"2021-02-23T00:00:00Z","timestamp":1614038400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21978236, 21776228, and 21978229"],"award-info":[{"award-number":["21978236, 21776228, and 21978229"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Key Research and Development Program of Shaanxi","award":["2019ZDLSF03-01-02 and 2019NY140"],"award-info":[{"award-number":["2019ZDLSF03-01-02 and 2019NY140"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Agric. Food Chem."],"published-print":{"date-parts":[[2021,3,17]]},"DOI":"10.1021\/acs.jafc.0c07805","type":"journal-article","created":{"date-parts":[[2021,2,23]],"date-time":"2021-02-23T20:05:01Z","timestamp":1614110701000},"page":"3082-3093","source":"Crossref","is-referenced-by-count":73,"title":["Ginsenoside Rk3 Ameliorates Obesity-Induced Colitis by Regulating of Intestinal Flora and the TLR4\/NF-\u03baB Signaling Pathway in C57BL\/6 Mice"],"prefix":"10.1021","volume":"69","author":[{"given":"Hongwei","family":"Chen","sequence":"first","affiliation":[{"name":"Shaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Xi\u2019an 710069, China"},{"name":"Shaanxi R&D Center of Biomaterials and Fermentation Engineering, School of Chemical Engineering, Northwest University, Xi\u2019an 710069, China"},{"name":"Biotech & Biomed Research Institute, Northwest University, 229 North Taibai Road, Xi\u2019an 710069, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haixia","family":"Yang","sequence":"additional","affiliation":[{"name":"Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3057-6997","authenticated-orcid":true,"given":"Jianjun","family":"Deng","sequence":"additional","affiliation":[{"name":"Shaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Xi\u2019an 710069, China"},{"name":"Shaanxi R&D Center of Biomaterials and Fermentation Engineering, School of Chemical Engineering, Northwest University, Xi\u2019an 710069, China"},{"name":"Biotech & Biomed Research Institute, Northwest University, 229 North Taibai Road, Xi\u2019an 710069, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9798-1674","authenticated-orcid":true,"given":"Daidi","family":"Fan","sequence":"additional","affiliation":[{"name":"Shaanxi Key Laboratory of Degradable Biomedical Materials, School of Chemical Engineering, Northwest University, Xi\u2019an 710069, China"},{"name":"Shaanxi R&D Center of Biomaterials and Fermentation Engineering, School of Chemical Engineering, Northwest University, Xi\u2019an 710069, China"},{"name":"Biotech & Biomed Research Institute, Northwest University, 229 North Taibai Road, Xi\u2019an 710069, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2021,2,23]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.10.001"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mpg.0000163736.30261.82"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i5.1238"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00098.2010"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/nature13959"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1126\/science.311.5760.464"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2007.616"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/s41366-018-0166-2"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/srep28990"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-018-0025-6"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i5.1192"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-014-0189-7"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.2174\/0929867324666171009121702"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2013.03.007"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0504978102"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.2337\/db07-1403"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.127.6.1617"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1128\/aem.02340-06"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-24716-3_11"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-007-0791-0"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1136\/gut.24.5.399"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2008.165886"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1038\/35100529"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1038\/nrd914"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/s1734-1140(11)70575-8"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.4314\/ajtcam.v2i2.31116"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2020.104746"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.2991\/efood.k.200512.001"},{"key":"ref29\/cit29","first-page":"RA187","volume":"10","author":"Zhou W.","year":"2004","journal-title":"Med. Sci. Monit."},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1039\/c7fo00385d"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0216759"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1039\/c9fo00095j"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.2001.281.3.r1013"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.0c00605"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.jff.2018.12.003"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(12)60026-9"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.2337\/db06-1491"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00107.2017"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.r067629"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-019-0157-3"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2012.01921.x"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2019.01.017"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1172\/jci57132"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0047713"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.00423"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2014-306928"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30036"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/s0016-5085(99)70450-6"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2013.155"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1038\/nature11450"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1038\/nature12331"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.3390\/nu10040432"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1161\/circresaha.106.142851"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2011.01.012"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1126\/science.1227568"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.r066514"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1038\/nm1166"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1038\/nature21363"}],"container-title":["Journal of Agricultural and Food Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.0c07805","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T22:06:29Z","timestamp":1682460389000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jafc.0c07805"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,23]]},"references-count":58,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,3,17]]}},"alternative-id":["10.1021\/acs.jafc.0c07805"],"URL":"https:\/\/doi.org\/10.1021\/acs.jafc.0c07805","relation":{},"ISSN":["0021-8561","1520-5118"],"issn-type":[{"value":"0021-8561","type":"print"},{"value":"1520-5118","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,23]]}}}