{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T15:10:04Z","timestamp":1793286604615,"version":"4.5.0"},"reference-count":48,"publisher":"American Chemical Society (ACS)","issue":"25","license":[{"start":{"date-parts":[[2021,6,21]],"date-time":"2021-06-21T00:00:00Z","timestamp":1624233600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,6,21]],"date-time":"2021-06-21T00:00:00Z","timestamp":1624233600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,6,21]],"date-time":"2021-06-21T00:00:00Z","timestamp":1624233600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81760769"],"award-info":[{"award-number":["81760769"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ningxia Hui Autonomous Region key research and development program","award":["2020BFG03007"],"award-info":[{"award-number":["2020BFG03007"]}]},{"name":"Fundamental Research Funds for the Youthful Teacher of Beijing University of Chinese Medicine","award":["2018-JYBZZ-JS017"],"award-info":[{"award-number":["2018-JYBZZ-JS017"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Agric. Food Chem."],"published-print":{"date-parts":[[2021,6,30]]},"DOI":"10.1021\/acs.jafc.1c02362","type":"journal-article","created":{"date-parts":[[2021,6,21]],"date-time":"2021-06-21T16:29:02Z","timestamp":1624292942000},"page":"7074-7083","source":"Crossref","is-referenced-by-count":27,"title":["Dietary Ursolic Acid Prevents Alcohol-Induced Liver Injury via Gut\u2013Liver Axis Homeostasis Modulation: The Key Role of Microbiome Manipulation"],"prefix":"10.1021","volume":"69","author":[{"given":"Xin","family":"Yan","sequence":"first","affiliation":[{"name":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"},{"name":"Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueyang","family":"Ren","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"},{"name":"Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyun","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"},{"name":"Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"},{"name":"Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiamu","family":"Ma","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"},{"name":"Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruolan","family":"Song","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"},{"name":"Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiuhuan","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"},{"name":"Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Dong","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"},{"name":"Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiqi","family":"Fan","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"},{"name":"Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wei","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"},{"name":"Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axiang","family":"Yu","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"},{"name":"Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9552-6288","authenticated-orcid":true,"given":"Gaimei","family":"She","sequence":"additional","affiliation":[{"name":"School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"},{"name":"Beijing Key Laboratory for Quality Evaluation of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2021,6,21]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/5623683"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.20471\/acc.2016.55.01.19"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1111\/ajad.12420"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2016.01.014"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1080\/08870446.2013.828293"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.cld.2018.09.011"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.cld.2012.08.004"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.0c01467"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.0c01947"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2012.08.011"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2017.10.028"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2016.01.017"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.3390\/molecules201119721"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.8b04116"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.etap.2014.03.011"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/jf0520342"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2005.05.060"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1573(200005)14:3<163::AID-PTR588>3.0.CO;2-D"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2014.10.042"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1093\/alcalc\/agx025"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-018-0099-1"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00354.2012"},{"issue":"3","key":"ref23\/cit23","first-page":"997","volume":"294","author":"Banan A.","year":"2000","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"3","key":"ref24\/cit24","first-page":"1075","volume":"291","author":"Banan A.","year":"1999","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21138"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2017.0067"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.10.019"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.7b03377"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2018.07.002"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1038\/s41366-019-0332-1"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201700741RR"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/710381"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-014-0189-7"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2008.10.028"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0053028"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.3390\/nu12061623"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2006.050617"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2008.10.028"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.3945\/jn.112.164947"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.102.047415"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-09045-z"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2015.212"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13164"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-205-43703"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20184568"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24018"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1039\/C9FO03015H"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.14598"}],"container-title":["Journal of Agricultural and Food Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.1c02362","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T09:41:11Z","timestamp":1682415671000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jafc.1c02362"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,21]]},"references-count":48,"journal-issue":{"issue":"25","published-print":{"date-parts":[[2021,6,30]]}},"alternative-id":["10.1021\/acs.jafc.1c02362"],"URL":"https:\/\/doi.org\/10.1021\/acs.jafc.1c02362","relation":{},"ISSN":["0021-8561","1520-5118"],"issn-type":[{"value":"0021-8561","type":"print"},{"value":"1520-5118","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,21]]}}}