{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T20:48:16Z","timestamp":1793479696278,"version":"4.5.0"},"reference-count":52,"publisher":"American Chemical Society (ACS)","issue":"51","license":[{"start":{"date-parts":[[2022,12,15]],"date-time":"2022-12-15T00:00:00Z","timestamp":1671062400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,12,15]],"date-time":"2022-12-15T00:00:00Z","timestamp":1671062400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,12,15]],"date-time":"2022-12-15T00:00:00Z","timestamp":1671062400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["2022YFD1300700"],"award-info":[{"award-number":["2022YFD1300700"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32030101"],"award-info":[{"award-number":["32030101"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32272914"],"award-info":[{"award-number":["32272914"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U21A20252"],"award-info":[{"award-number":["U21A20252"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Heilongjiang Touyan Innovation Team Program"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Agric. Food Chem."],"published-print":{"date-parts":[[2022,12,28]]},"DOI":"10.1021\/acs.jafc.2c05381","type":"journal-article","created":{"date-parts":[[2022,12,15]],"date-time":"2022-12-15T15:40:07Z","timestamp":1671118807000},"page":"16080-16095","source":"Crossref","is-referenced-by-count":36,"title":["Gut-Derived Metabolites from Dietary Tryptophan Supplementation Quench Intestinal Inflammation through the AMPK-SIRT1-Autophagy Pathway"],"prefix":"10.1021","volume":"70","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2272-2074","authenticated-orcid":true,"given":"Nan","family":"Gao","sequence":"first","affiliation":[{"name":"College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Yang","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siqi","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyang","family":"Fang","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiujing","family":"Dou","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Licong","family":"Zhang","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2830-7509","authenticated-orcid":true,"given":"Anshan","family":"Shan","sequence":"additional","affiliation":[{"name":"College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,12,15]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2013.35"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biotechadv.2022.107962"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2009.09.020"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0505256102"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.202000461"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1038\/nature12820"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2014-306928"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1601247"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.1c00706"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2019.08.004"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2017.1402992"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2019.1635384"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.20536"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-019-1634-x"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2015.10.037"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1007\/s00726-008-0225-4"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2016.12.019"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114518000740"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.1c07761"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.14348\/molcells.2015.2193"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2021.1903826"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.1999.277.4.G785"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.22397"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2018.05.003"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201899595"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.1c05820"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1111\/jfbc.14126"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.202001213"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.3390\/nu14142809"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2017.06.007"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2022.113811"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1038\/nature11228"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2022.09.038"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1002\/btm2.10446"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2003.08.028"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2017.11.003"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2016.04.049"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3181a23dbe"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.23925"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2020.11338"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2016.03.046"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclepro.2022.131366"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1039\/C8FO01025K"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1038\/s41574-019-0205-7"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.8b03343"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms8111630"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.3390\/ani8110189"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.02755"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1111\/cas.12705"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2019.07.013"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2016.00068"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2019.110805"}],"container-title":["Journal of Agricultural and Food Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.2c05381","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.2c05381","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T12:31:20Z","timestamp":1682425880000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jafc.2c05381"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,15]]},"references-count":52,"journal-issue":{"issue":"51","published-print":{"date-parts":[[2022,12,28]]}},"alternative-id":["10.1021\/acs.jafc.2c05381"],"URL":"https:\/\/doi.org\/10.1021\/acs.jafc.2c05381","relation":{},"ISSN":["0021-8561","1520-5118"],"issn-type":[{"value":"0021-8561","type":"print"},{"value":"1520-5118","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,15]]}}}