{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T18:24:39Z","timestamp":1793039079478,"version":"4.5.0"},"reference-count":50,"publisher":"American Chemical Society (ACS)","issue":"49","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100008562","name":"Nanjing Agricultural University","doi-asserted-by":"publisher","award":["XUEKEN2023039"],"award-info":[{"award-number":["XUEKEN2023039"]}],"id":[{"id":"10.13039\/501100008562","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["12005248"],"award-info":[{"award-number":["12005248"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32071264"],"award-info":[{"award-number":["32071264"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Agric. Food Chem."],"published-print":{"date-parts":[[2023,12,13]]},"DOI":"10.1021\/acs.jafc.3c05216","type":"journal-article","created":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T12:37:32Z","timestamp":1701434252000},"page":"19385-19395","source":"Crossref","is-referenced-by-count":12,"title":["Discovery of Novel <i>Rhizoctonia solani<\/i> DHFR Inhibitors as Fungicides Using Virtual Screening"],"prefix":"10.1021","volume":"71","author":[{"given":"Ruirui","family":"Feng","sequence":"first","affiliation":[{"name":"College of Science, Nanjing Agricultural University, Nanjing 210095, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Sun","sequence":"additional","affiliation":[{"name":"Key Lab of Organic-Based Fertilizers of China and Jiangsu Provincial Key Lab for Solid Organic Waste Utilization, Joint International Research Laboratory of Soil Health, Nanjing Agricultural University, Nanjing 210095, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengkai","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institute of Advanced Science Facilities, Shenzhen 518107, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3868-567X","authenticated-orcid":true,"given":"Erzheng","family":"Su","sequence":"additional","affiliation":[{"name":"College of Light Industry and Food Engineering, Nanjing Forestry University, Nanjing 210037, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4459-9142","authenticated-orcid":true,"given":"Andrey","family":"Kovalevsky","sequence":"additional","affiliation":[{"name":"Neutron Scattering Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Zhang","sequence":"additional","affiliation":[{"name":"State & Local Joint Engineering Research Center of Green Pesticide Invention and Application, College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brad C.","family":"Bennett","sequence":"additional","affiliation":[{"name":"Biological and Environmental Science Department, Samford University, Birmingham, Alabama 35229, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qirong","family":"Shen","sequence":"additional","affiliation":[{"name":"Key Lab of Organic-Based Fertilizers of China and Jiangsu Provincial Key Lab for Solid Organic Waste Utilization, Joint International Research Laboratory of Soil Health, Nanjing Agricultural University, Nanjing 210095, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8309-0341","authenticated-orcid":true,"given":"Qun","family":"Wan","sequence":"additional","affiliation":[{"name":"Key Lab of Organic-Based Fertilizers of China and Jiangsu Provincial Key Lab for Solid Organic Waste Utilization, Joint International Research Laboratory of Soil Health, Nanjing Agricultural University, Nanjing 210095, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,12,1]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rsci.2016.01.005"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1020811019189"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.17221\/9\/2017-PPS"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/S1671-2927(07)60149-7"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-08-029223-6.50048-3"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-7348.2012.00569.x"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/bi00387a052"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2020.112268"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.2174\/0929867326666191016151018"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.2174\/092986706775527938"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/jm010548w"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/S1367-5931(00)00217-9"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2000585117"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/S1359-6446(02)00004-1"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2018.04.022"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-017-1686-9"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/15.4.305"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.5b00559"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1002\/minf.201100020"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-409X(00)00129-0"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-1414"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkl124"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.2174\/1381612033453712"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008100132405"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/bi00492a021"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-03819-2"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1107\/S0021889892009944"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkh398"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.str.2016.11.012"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/ci200227u"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.21334"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkab255"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsb.2009.01.001"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1007\/s000110050455"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1111\/1574-6968.12065"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.softx.2015.06.001"},{"key":"ref37\/cit37","unstructured":"Case, D. A.; Anandakrishnan, R.; Ayers, K.; Betz, R.; Zhang, W. Ambertools18; University of California: San Francisco, 2018."},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jctc.1c00645"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/ci100275a"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1021\/ct300418h"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1307130110"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2013.832635"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1204556109"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1021\/jm101020z"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1007\/s10822-007-9165-4"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1107\/S0907444904030422"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1021\/bi982728m"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.9b00222"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1999.3328"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1111\/jph.12591"}],"container-title":["Journal of Agricultural and Food Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.3c05216","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.3c05216","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,13]],"date-time":"2023-12-13T11:44:26Z","timestamp":1702467866000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jafc.3c05216"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,1]]},"references-count":50,"journal-issue":{"issue":"49","published-print":{"date-parts":[[2023,12,13]]}},"alternative-id":["10.1021\/acs.jafc.3c05216"],"URL":"https:\/\/doi.org\/10.1021\/acs.jafc.3c05216","relation":{},"ISSN":["0021-8561","1520-5118"],"issn-type":[{"value":"0021-8561","type":"print"},{"value":"1520-5118","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,1]]}}}