{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:42:27Z","timestamp":1792784547590,"version":"4.5.0"},"reference-count":39,"publisher":"American Chemical Society (ACS)","issue":"8","license":[{"start":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T00:00:00Z","timestamp":1739318400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T00:00:00Z","timestamp":1739318400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T00:00:00Z","timestamp":1739318400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFC2100900"],"award-info":[{"award-number":["2021YFC2100900"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project","award":["TSBICIP-KJGG-020"],"award-info":[{"award-number":["TSBICIP-KJGG-020"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Agric. Food Chem."],"published-print":{"date-parts":[[2025,2,26]]},"DOI":"10.1021\/acs.jafc.4c09781","type":"journal-article","created":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T11:49:51Z","timestamp":1739360991000},"page":"4755-4763","source":"Crossref","is-referenced-by-count":6,"title":["Converting\n                    <i>Bacillus subtilis<\/i>\n                    168 to a Synthetic Methylotroph by Combinatorial Metabolic Regulation Strategies"],"prefix":"10.1021","volume":"73","author":[{"given":"Qingfang","family":"Meng","sequence":"first","affiliation":[{"name":"Tianjin University of Science & Technology","place":["Tianjin, China"]},{"name":"College of Food Science & Engineering","place":["Tianjin, China"]},{"name":"State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing","place":["Tianjin, China"]},{"name":"Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dexin","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing","place":["Tianjin, China"]},{"name":"Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences","place":["Tianjin, China"]},{"name":"National Center of Technology Innovation for Synthetic Biology","place":["Tianjin, China"]},{"name":"Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoping","family":"Fu","sequence":"additional","affiliation":[{"name":"National Center of Technology Innovation for Synthetic Biology","place":["Tianjin, China"]},{"name":"Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences","place":["Tianjin, China"]},{"name":"Industrial Enzymes National Engineering Research Center","place":["Tianjin, China"]},{"name":"Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weitao","family":"Geng","sequence":"additional","affiliation":[{"name":"Tianjin University of Science & Technology","place":["Tianjin, China"]},{"name":"College of Food Science & Engineering","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7780-0784","authenticated-orcid":true,"given":"Hongchen","family":"Zheng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing","place":["Tianjin, China"]},{"name":"Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences","place":["Tianjin, China"]},{"name":"National Center of Technology Innovation for Synthetic Biology","place":["Tianjin, China"]},{"name":"Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences","place":["Tianjin, China"]},{"name":"Industrial Enzymes National Engineering Research Center","place":["Tianjin, China"]},{"name":"Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6202-8613","authenticated-orcid":true,"given":"Wenqin","family":"Bai","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing","place":["Tianjin, China"]},{"name":"Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences","place":["Tianjin, China"]},{"name":"National Center of Technology Innovation for Synthetic Biology","place":["Tianjin, China"]},{"name":"Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences","place":["Tianjin, China"]},{"name":"Industrial Enzymes National Engineering Research Center","place":["Tianjin, China"]},{"name":"Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences","place":["Tianjin, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,2,12]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-021-00836-0"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rser.2015.01.010"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-014-6224-3"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-014-6240-3"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1002\/bbb.1773"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibtech.2019.12.013"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymben.2021.01.009"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1186\/s12934-023-02275-z"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.synbio.2023.06.001"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.copbio.2015.01.007"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymben.2018.07.011"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymben.2017.11.015"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.biortech.2017.05.100"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiotec.2021.12.005"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.biotechadv.2016.11.003"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.copbio.2019.10.002"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymben.2018.08.010"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymben.2016.10.015"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1039\/C6RA27038G"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymben.2014.12.008"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03937-y"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.03110-14"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.07.010"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1128\/jb.99.1.70-77.1969"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1186\/s12934-022-01994-z"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1115485109"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2021.07.005"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1042\/bj0550416"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymben.2021.09.005"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10020220"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.engmic.2023.100081"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-38304-z"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1601797113"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-46655-4"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymben.2019.12.006"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymben.2020.03.003"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-19235-5"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-020-0954-9"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-04795-4"}],"container-title":["Journal of Agricultural and Food Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.4c09781","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.4c09781","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,26]],"date-time":"2025-02-26T04:15:54Z","timestamp":1740543354000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jafc.4c09781"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,12]]},"references-count":39,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,2,26]]}},"alternative-id":["10.1021\/acs.jafc.4c09781"],"URL":"https:\/\/doi.org\/10.1021\/acs.jafc.4c09781","relation":{},"ISSN":["0021-8561","1520-5118"],"issn-type":[{"value":"0021-8561","type":"print"},{"value":"1520-5118","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,12]]}}}