{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T00:08:57Z","timestamp":1789085337329,"version":"build-2803163510"},"reference-count":45,"publisher":"American Chemical Society (ACS)","license":[{"start":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T00:00:00Z","timestamp":1741910400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T00:00:00Z","timestamp":1741910400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T00:00:00Z","timestamp":1741910400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100010023","name":"Jiangsu Provincial Department of Education","doi-asserted-by":"publisher","award":["22KJB550003"],"award-info":[{"award-number":["22KJB550003"]}],"id":[{"id":"10.13039\/501100010023","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20211292"],"award-info":[{"award-number":["BK20211292"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32072221"],"award-info":[{"award-number":["32072221"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32272318"],"award-info":[{"award-number":["32272318"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Agric. Food Chem."],"DOI":"10.1021\/acs.jafc.4c12660","type":"journal-article","created":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T10:41:45Z","timestamp":1741948905000},"source":"Crossref","is-referenced-by-count":17,"title":["Polysaccharide from\n                    <i>Momordica charantia<\/i>\n                    L. Alleviates Type 2 Diabetes Mellitus in Mice by Activating the IRS1\/PI3K\/Akt and AMPK Signaling Pathways and Regulating the Gut Microbiota"],"prefix":"10.1021","author":[{"given":"Yanhui","family":"Zhang","sequence":"first","affiliation":[{"name":"College of Food Science and Engineering\/Collaborative Innovation Center for Modern Grain Circulation and Safety\/Key Laboratory of Grains and Oils Quality Control and Processing","place":["Nanjing, China"]},{"name":"Nanjing University of Finance and Economics","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yubo","family":"Cao","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering\/Collaborative Innovation Center for Modern Grain Circulation and Safety\/Key Laboratory of Grains and Oils Quality Control and Processing","place":["Nanjing, China"]},{"name":"Nanjing University of Finance and Economics","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering\/Collaborative Innovation Center for Modern Grain Circulation and Safety\/Key Laboratory of Grains and Oils Quality Control and Processing","place":["Nanjing, China"]},{"name":"Nanjing University of Finance and Economics","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luanfeng","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering\/Collaborative Innovation Center for Modern Grain Circulation and Safety\/Key Laboratory of Grains and Oils Quality Control and Processing","place":["Nanjing, China"]},{"name":"Nanjing University of Finance and Economics","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Xiong","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering\/Collaborative Innovation Center for Modern Grain Circulation and Safety\/Key Laboratory of Grains and Oils Quality Control and Processing","place":["Nanjing, China"]},{"name":"Nanjing University of Finance and Economics","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinchun","family":"Shen","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering\/Collaborative Innovation Center for Modern Grain Circulation and Safety\/Key Laboratory of Grains and Oils Quality Control and Processing","place":["Nanjing, China"]},{"name":"Nanjing University of Finance and Economics","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1091-3084","authenticated-orcid":true,"given":"Haizhao","family":"Song","sequence":"additional","affiliation":[{"name":"College of Food Science and Engineering\/Collaborative Innovation Center for Modern Grain Circulation and Safety\/Key Laboratory of Grains and Oils Quality Control and Processing","place":["Nanjing, China"]},{"name":"Nanjing University of Finance and Economics","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,3,14]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2020.110514"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)30058-2"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.8b05338"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1111\/dme.13040"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1111\/1541-4337.12441"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2016.08.022"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.11648\/j.ijnfs.20150401.21"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2023.216179"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1007\/s13105-019-00706-3"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-07188-9"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1017\/S1462399411002109"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1007\/s10555-022-10027-5"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1909311116"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/5110276"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1126\/science.aam9949"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2020.06.011"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-023-03029-y"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1039\/C7FO01346A"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27186061"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.138300"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.3390\/diabetology2020004"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-44088-z"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2007.09.001"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1039\/C8FO01117F"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.624404"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1186\/s13020-019-0281-6"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.2174\/0929867324666170426142826"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1007\/s00424-020-02417-x"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1042\/BST20221066"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2019.02.007"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgab362"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.3390\/cells12040650"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1006962107"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2012.06.019"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1097\/MOL.0b013e328328d0a4"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0041079"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.jff.2018.05.061"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1101\/2020.12.08.416487"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2023.132057"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-023-06466-x"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1021\/jf4040942"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1005963107"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1038\/nrm.2016.25"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26237066"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2022.111331"}],"container-title":["Journal of Agricultural and Food Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.4c12660","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.4c12660","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T04:33:30Z","timestamp":1742963610000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jafc.4c12660"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,14]]},"references-count":45,"alternative-id":["10.1021\/acs.jafc.4c12660"],"URL":"https:\/\/doi.org\/10.1021\/acs.jafc.4c12660","relation":{},"ISSN":["0021-8561","1520-5118"],"issn-type":[{"value":"0021-8561","type":"print"},{"value":"1520-5118","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,14]]},"article-number":"acs.jafc.4c12660"}}