{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T18:00:33Z","timestamp":1787508033894,"version":"build-2736575974"},"reference-count":36,"publisher":"American Chemical Society (ACS)","issue":"41","license":[{"start":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T00:00:00Z","timestamp":1759449600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T00:00:00Z","timestamp":1759449600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T00:00:00Z","timestamp":1759449600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100011332","name":"University of Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["WIUCASQD2023011"],"award-info":[{"award-number":["WIUCASQD2023011"]}],"id":[{"id":"10.13039\/501100011332","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LBY22H180005"],"award-info":[{"award-number":["LBY22H180005"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Agric. Food Chem."],"published-print":{"date-parts":[[2025,10,15]]},"DOI":"10.1021\/acs.jafc.5c05650","type":"journal-article","created":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T20:11:16Z","timestamp":1759522276000},"page":"26060-26072","source":"Crossref","is-referenced-by-count":4,"title":["Galangin Alleviates Intervertebral Disc Degeneration via the Nrf2\/NF-\u03baB Pathway"],"prefix":"10.1021","volume":"73","author":[{"given":"Linjie","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Orthopaedics","place":["Wenzhou, China"]},{"name":"The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University","place":["Wenzhou, China"]},{"name":"Key Laboratory of Orthopaedics of Zhejiang Province","place":["Wenzhou, China"]},{"name":"The Second School of Medicine","place":["Wenzhou, China"]},{"name":"Wenzhou Medical University","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suyu","family":"Ying","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics","place":["Wenzhou, China"]},{"name":"The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University","place":["Wenzhou, China"]},{"name":"Key Laboratory of Orthopaedics of Zhejiang Province","place":["Wenzhou, China"]},{"name":"The Second School of Medicine","place":["Wenzhou, China"]},{"name":"Wenzhou Medical University","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenyu","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics","place":["Wenzhou, China"]},{"name":"The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University","place":["Wenzhou, China"]},{"name":"Key Laboratory of Orthopaedics of Zhejiang Province","place":["Wenzhou, China"]},{"name":"The Second School of Medicine","place":["Wenzhou, China"]},{"name":"Wenzhou Medical University","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongye","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics","place":["Wenzhou, China"]},{"name":"The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University","place":["Wenzhou, China"]},{"name":"Key Laboratory of Orthopaedics of Zhejiang Province","place":["Wenzhou, China"]},{"name":"The Second School of Medicine","place":["Wenzhou, China"]},{"name":"Wenzhou Medical University","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxin","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics","place":["Wenzhou, China"]},{"name":"The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University","place":["Wenzhou, China"]},{"name":"Key Laboratory of Orthopaedics of Zhejiang Province","place":["Wenzhou, China"]},{"name":"The Second School of Medicine","place":["Wenzhou, China"]},{"name":"Wenzhou Medical University","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinzhou","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics","place":["Wenzhou, China"]},{"name":"The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University","place":["Wenzhou, China"]},{"name":"Key Laboratory of Orthopaedics of Zhejiang Province","place":["Wenzhou, China"]},{"name":"The Second School of Medicine","place":["Wenzhou, China"]},{"name":"Wenzhou Medical University","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics","place":["Wenzhou, China"]},{"name":"The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University","place":["Wenzhou, China"]},{"name":"Key Laboratory of Orthopaedics of Zhejiang Province","place":["Wenzhou, China"]},{"name":"The Second School of Medicine","place":["Wenzhou, China"]},{"name":"Wenzhou Medical University","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangcheng","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Science","place":["Wenzhou, China"]},{"name":"Wenzhou Medical University","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chencheng","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics","place":["Wenzhou, China"]},{"name":"The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University","place":["Wenzhou, China"]},{"name":"Key Laboratory of Orthopaedics of Zhejiang Province","place":["Wenzhou, China"]},{"name":"The Second School of Medicine","place":["Wenzhou, China"]},{"name":"Wenzhou Medical University","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics","place":["Wenzhou, China"]},{"name":"The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University","place":["Wenzhou, China"]},{"name":"Key Laboratory of Orthopaedics of Zhejiang Province","place":["Wenzhou, China"]},{"name":"The Second School of Medicine","place":["Wenzhou, China"]},{"name":"Wenzhou Medical University","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongsheng","family":"Jiang","sequence":"additional","affiliation":[{"name":"The Affiliated Xiangshan Hospital of Wenzhou Medical University","place":["Ningbo, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics","place":["Wenzhou, China"]},{"name":"The Second Affiliated Hospital and Yuying Children\u2019s Hospital of Wenzhou Medical University","place":["Wenzhou, China"]},{"name":"Zhejiang Engineering Research Center for Tissue Repair Materials","place":["Wenzhou, China"]},{"name":"Wenzhou Institute of University of Chinese Academy of Sciences","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,10,3]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)30480-X"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(18)30488-4"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2020.101227"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000000832"},{"key":"ref4\/cit4a","doi-asserted-by":"publisher","DOI":"10.1007\/s12178-014-9253-8"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000231761.73859.2c"},{"key":"ref5\/cit5a","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-020-00253-0"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-019-2085-6"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2015.09.019"},{"key":"ref7\/cit7a","doi-asserted-by":"publisher","DOI":"10.1016\/j.jot.2025.01.013"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2013.160"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.F.00019"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2025.02.052"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1080\/13510002.2016.1273437"},{"key":"ref11\/cit11a","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2017.05.034"},{"key":"ref11\/cit11b","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.111808"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.111410"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.3390\/biom9080346"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1080\/10715762.2017.1381694"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2016.11.005"},{"key":"ref15\/cit15a","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.13360"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2017.03.015"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.4025"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1039\/D0FO03353G"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e31817c64a9"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202304722"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2023.2274205"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2022.120396"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1186\/ar2275"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000149186.63457.20"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-015-0676-3"},{"key":"ref25\/cit25a","doi-asserted-by":"publisher","DOI":"10.1039\/C9FO02552A"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1042\/BSR20191673"},{"key":"ref26\/cit26a","doi-asserted-by":"publisher","DOI":"10.1007\/s12015-023-10570-w"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.9b00171"},{"key":"ref27\/cit27a","doi-asserted-by":"publisher","DOI":"10.1002\/biof.1507"}],"container-title":["Journal of Agricultural and Food Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.5c05650","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.5c05650","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T08:15:41Z","timestamp":1760516141000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jafc.5c05650"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,3]]},"references-count":36,"journal-issue":{"issue":"41","published-print":{"date-parts":[[2025,10,15]]}},"alternative-id":["10.1021\/acs.jafc.5c05650"],"URL":"https:\/\/doi.org\/10.1021\/acs.jafc.5c05650","relation":{},"ISSN":["0021-8561","1520-5118"],"issn-type":[{"value":"0021-8561","type":"print"},{"value":"1520-5118","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,3]]}}}