{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T04:23:57Z","timestamp":1791260637148,"version":"4.1.0"},"reference-count":53,"publisher":"American Chemical Society (ACS)","issue":"7","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100020084","name":"Guangzhou Municipal Science and Technology Bureau","doi-asserted-by":"publisher","award":["202002020032"],"award-info":[{"award-number":["202002020032"]}],"id":[{"id":"10.13039\/501100020084","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82574652"],"award-info":[{"award-number":["82574652"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024A1515012135"],"award-info":[{"award-number":["2024A1515012135"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Agric. Food Chem."],"published-print":{"date-parts":[[2026,2,25]]},"DOI":"10.1021\/acs.jafc.5c11938","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T02:38:44Z","timestamp":1770863924000},"page":"6193-6207","source":"Crossref","is-referenced-by-count":4,"title":["Activating PXR by Curcumol Ameliorates DSS-Induced Ulcerative Colitis via Transcriptional Repression of STING Signaling"],"prefix":"10.1021","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-3999-4872","authenticated-orcid":true,"given":"Wenmin","family":"Xie","sequence":"first","affiliation":[{"name":"State Key Laboratory of Traditional Chinese Medicine Syndrome, School of Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangzhou University of Chinese Medicine","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4147-7791","authenticated-orcid":true,"given":"Ting","family":"Yang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Traditional Chinese Medicine Syndrome, School of Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangzhou University of Chinese Medicine","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8792-7004","authenticated-orcid":true,"given":"Fei","family":"Mo","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Traditional Chinese Medicine Syndrome, School of Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangzhou University of Chinese Medicine","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6011-4853","authenticated-orcid":true,"given":"Wanting","family":"Meng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Traditional Chinese Medicine Syndrome, School of Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangzhou University of Chinese Medicine","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-2563-8882","authenticated-orcid":true,"given":"Linsheng","family":"Xu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Traditional Chinese Medicine Syndrome, School of Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangzhou University of Chinese Medicine","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6027-0278","authenticated-orcid":true,"given":"Jian","family":"Liang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Traditional Chinese Medicine Syndrome, School of Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangzhou University of Chinese Medicine","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6165-4313","authenticated-orcid":true,"given":"Changhui","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Traditional Chinese Medicine Syndrome, School of Pharmaceutical Sciences","place":["Guangzhou, China"]},{"name":"Guangzhou University of Chinese Medicine","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-5358-1505","authenticated-orcid":true,"given":"Yanhua","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Acupuncture-rehabilitation","place":["Guangzhou, China"]},{"name":"The Third Affiliated Hospital of Guangzhou University of Chinese Medicine","place":["Guangzhou, China"]},{"name":"Department of Rehabilitation Medicine","place":["Guangzhou, China"]},{"name":"Guangzhou-Liwan Hospital of Chinese Medicine","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,2,11]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)00966-2"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32448-0"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/nature11582"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.848344"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2018-317571"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.3390\/cells12242846"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2017.52"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2001.29694"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2012-303207"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0b013e318281f54e"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjy215"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(18)30231-0"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(24)00044-X"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1606910"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.3390\/cells9112395"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2020551118"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2019.09.010"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1124\/pharmrev.124.000978"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3558"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1038\/nature12306"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2021.05.008"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1818281116"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2019.02.055"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2017.10.007"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-50656-5"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.34716"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-021-03015-4"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.3390\/ijms160819851"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.6158"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2017.06.037"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2018.09.007"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmgh.2015.01.006"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1093\/gastro\/goae021"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v23.i33.6016"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.3390\/nu10091196"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.6616"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2025.156752"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1111\/bph.14424"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2020-321774"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2017.044"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2019.1635384"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2013.11.007"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.01070"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/2624941"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2021.107920"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21072346"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1002\/eji.202048777"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izab217"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.11.101"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2021.05.008"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1111\/acel.13622"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2022.102305"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202308771"}],"container-title":["Journal of Agricultural and Food Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.5c11938","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.5c11938","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T08:56:14Z","timestamp":1773132974000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jafc.5c11938"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,11]]},"references-count":53,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,2,25]]}},"alternative-id":["10.1021\/acs.jafc.5c11938"],"URL":"https:\/\/doi.org\/10.1021\/acs.jafc.5c11938","relation":{},"ISSN":["0021-8561","1520-5118"],"issn-type":[{"value":"0021-8561","type":"print"},{"value":"1520-5118","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,11]]}}}