{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:42:31Z","timestamp":1792784551701,"version":"4.5.0"},"reference-count":56,"publisher":"American Chemical Society (ACS)","issue":"12","license":[{"start":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T00:00:00Z","timestamp":1773792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T00:00:00Z","timestamp":1773792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T00:00:00Z","timestamp":1773792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100007219","name":"Natural Science Foundation of Shanghai Municipality","doi-asserted-by":"publisher","award":["23ZR1416500"],"award-info":[{"award-number":["23ZR1416500"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2018YFA0900300"],"award-info":[{"award-number":["2018YFA0900300"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010040","name":"Taishan Scholar Project of Shandong Province","doi-asserted-by":"publisher","award":["tsqn202312316"],"award-info":[{"award-number":["tsqn202312316"]}],"id":[{"id":"10.13039\/501100010040","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003021","name":"East China University of Science and Technology","doi-asserted-by":"publisher","award":["JKVJ1231036"],"award-info":[{"award-number":["JKVJ1231036"]}],"id":[{"id":"10.13039\/501100003021","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shanghai Pilot Program for Basic Research","award":["22TQ1400100-14"],"award-info":[{"award-number":["22TQ1400100-14"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Agric. Food Chem."],"published-print":{"date-parts":[[2026,4,1]]},"DOI":"10.1021\/acs.jafc.5c17100","type":"journal-article","created":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T13:28:24Z","timestamp":1773840504000},"page":"10489-10500","source":"Crossref","is-referenced-by-count":1,"title":["Soft-Sensing-Guided Glucose\/\n                    <scp>l<\/scp>\n                    -Phenylalanine Cofeeding Strategy and Transcriptomic Analysis of the Optimal\n                    <scp>l<\/scp>\n                    -Phenylalanine Supply Range for Efficient \u03b2-Phenylethanol Biosynthesis in\n                    <i>Saccharomyces cerevisiae<\/i>"],"prefix":"10.1021","volume":"74","author":[{"given":"Chenghan","family":"Yang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Bioreactor Engineering, Qingdao Innovation Institute of East China University of Science and Technology","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]},{"name":"National Engineering Research Center for Biotechnology (Shanghai)","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huining","family":"Jia","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioreactor Engineering, Qingdao Innovation Institute of East China University of Science and Technology","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]},{"name":"National Engineering Research Center for Biotechnology (Shanghai)","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioreactor Engineering, Qingdao Innovation Institute of East China University of Science and Technology","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]},{"name":"National Engineering Research Center for Biotechnology (Shanghai)","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongrun","family":"Lan","sequence":"additional","affiliation":[{"name":"National Engineering Research Center for Biotechnology (Shanghai)","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huyang","family":"Chen","sequence":"additional","affiliation":[{"name":"National Engineering Research Center for Biotechnology (Shanghai)","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Bei","sequence":"additional","affiliation":[{"name":"National Engineering Research Center for Biotechnology (Shanghai)","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6564-9810","authenticated-orcid":true,"given":"Ali","family":"Mohsin","sequence":"additional","affiliation":[{"name":"National Engineering Research Center for Biotechnology (Shanghai)","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6406-1748","authenticated-orcid":true,"given":"Ju","family":"Chu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioreactor Engineering, Qingdao Innovation Institute of East China University of Science and Technology","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]},{"name":"National Engineering Research Center for Biotechnology (Shanghai)","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-4034-3564","authenticated-orcid":true,"given":"Haifeng","family":"Hang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioreactor Engineering, Qingdao Innovation Institute of East China University of Science and Technology","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]},{"name":"National Engineering Research Center for Biotechnology (Shanghai)","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiwei","family":"Tian","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioreactor Engineering, Qingdao Innovation Institute of East China University of Science and Technology","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6772-7306","authenticated-orcid":true,"given":"Yingping","family":"Zhuang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioreactor Engineering, Qingdao Innovation Institute of East China University of Science and Technology","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]},{"name":"National Engineering Research Center for Biotechnology (Shanghai)","place":["Shanghai, China"]},{"name":"East China University of Science and Technology","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,3,18]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/S0141-0229(02)00237-5"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.3390\/fermentation4030054"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3109\/9781420015034-5"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1080\/10412905.2008.9699429"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.molstruc.2024.139236"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1111\/ijfs.17480"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.biortech.2024.130867"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.biotechadv.2005.03.004"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.enzmictec.2019.109459"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.3390\/foods11010109"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2021.601963"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.fgb.2015.12.001"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1002\/bit.24993"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcatb.2003.10.014"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.3390\/foods14142444"},{"issue":"1","key":"ref16\/cit16","first-page":"1","volume":"59","author":"Etschmann M.","year":"2002","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/biot.202300740"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/bit.28936"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1002\/jctb.7582"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelechem.2021.115387"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1007\/s002530051552"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/S0032-9592(01)00223-0"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-014-7897-2"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1002\/btpr.280"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/bp034101n"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.3390\/beverages9030068"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/bit.28681"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/bit.28661"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1128\/aem.55.2.468-477.1989"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.fbp.2014.11.005"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1186\/s12934-023-02268-y"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.biortech.2015.12.069"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1080\/1828051X.2023.2281392"},{"key":"ref34\/cit34","doi-asserted-by":"crossref","unstructured":"Smulko, J.; Wr\u00f3bel, M. S.; Barman, I. Noise in biological Raman spectroscopy.\n                      Proc. 2015 Int. Conf. Noise Fluct. (ICNF)\n                      2015; pp 1\u20136.","DOI":"10.1109\/ICNF.2015.7288562"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1080\/05704928.2014.999936"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1002\/jrs.6225"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2005.05.042"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1080\/05704928.2019.1584567"},{"key":"ref39\/cit39","first-page":"79","volume":"79","author":"Maitra S.","year":"2008","journal-title":"CAS Discussion Paper Program: Applying Multivariate Statistical Models"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1136\/gpsych-2021-100662"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1139\/h04-031"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-019-02227-w"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1089\/omi.2010.0069"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiosc.2011.03.006"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.3390\/molecules29235761"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1021\/je201354k"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02625-07"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1111\/j.1567-1364.2012.00802.x"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms9010007"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.19.2.989"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.fm.2012.12.004"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.375360"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25031870"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/20.24.7209"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1128\/jb.172.8.4280-4287.1990"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02429-15"}],"container-title":["Journal of Agricultural and Food Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.5c17100","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.5c17100","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T08:13:20Z","timestamp":1775031200000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jafc.5c17100"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,18]]},"references-count":56,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2026,4,1]]}},"alternative-id":["10.1021\/acs.jafc.5c17100"],"URL":"https:\/\/doi.org\/10.1021\/acs.jafc.5c17100","relation":{},"ISSN":["0021-8561","1520-5118"],"issn-type":[{"value":"0021-8561","type":"print"},{"value":"1520-5118","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,18]]}}}