{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T14:04:37Z","timestamp":1789567477612,"version":"build-2803163510"},"reference-count":25,"publisher":"American Chemical Society (ACS)","issue":"36","license":[{"start":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,16]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Durian (Durio zibethinus) is well known for its odoriferous flavor character due to the presence of volatile sulfur compounds. However, its flavor behavior in the oral cavity has not yet been explored. Herein, the in vivo flavor composition of durian during oral processing was characterized, showing that the volatile flavor composition released into the oronasal cavity significantly differs from its headspace composition. It was surprising to observe that only &amp;lt;5 % of the total volatile content released during oral processing reaches the nasal cavity. Moreover, the sulfur-to-ester ratio of volatile components significantly decreases, suggesting that durian flavor may be perceived differently in retronasal versus orthonasal pathways. In vitro simulations further reveal that salivary mucin selectively binds to the sulfur content, changing the eventual volatile composition reaching the olfactory receptors during consumption. These findings hold significant implications toward understanding how oral processing impacts flavor composition and perception through retronasal and orthonasal mechanisms.<\/jats:p>","DOI":"10.1021\/acs.jafc.6c03345","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T18:20:04Z","timestamp":1788459604000},"page":"28622-28627","source":"Crossref","is-referenced-by-count":0,"title":["Saliva Selectively\nBinds to Pungent Odors during Oral\nConsumption of Durian"],"prefix":"10.1021","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1852-4067","authenticated-orcid":true,"given":"Aaron","family":"Thong","sequence":"first","affiliation":[{"name":"Agency for Science, Technology and Research (A*STAR) , , 31 Biopolis Way , Nanos, ,","place":["Singapore, Singapore, 138669"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derick","family":"Lee","sequence":"additional","affiliation":[{"name":"Agency for Science, Technology and Research (A*STAR) , , 31 Biopolis Way , Nanos, ,","place":["Singapore, Singapore, 138669"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1102-374X","authenticated-orcid":true,"given":"Shu Yi Geraldine","family":"Chan","sequence":"additional","affiliation":[{"name":"Agency for Science, Technology and Research (A*STAR) , , 31 Biopolis Way , Nanos, ,","place":["Singapore, Singapore, 138669"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9642-7368","authenticated-orcid":true,"given":"Michio","family":"Apollos","sequence":"additional","affiliation":[{"name":"Agency for Science, Technology and Research (A*STAR) , , 31 Biopolis Way , Nanos, ,","place":["Singapore, Singapore, 138669"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-2465-6413","authenticated-orcid":true,"given":"Michiryu","family":"Aquila","sequence":"additional","affiliation":[{"name":"Agency for Science, Technology and Research (A*STAR) , , 31 Biopolis Way , Nanos, ,","place":["Singapore, Singapore, 138669"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5888-8558","authenticated-orcid":true,"given":"Elijah Lev","family":"Wakefield","sequence":"additional","affiliation":[{"name":"University of Chicago , 5801 S. Ellis Avenue , , ,","place":["Chicago, Illinois, United States, 60637"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7000-1469","authenticated-orcid":true,"given":"Jianshe","family":"Chen","sequence":"additional","affiliation":[{"name":"Agency for Science, Technology and Research (A*STAR) , , 31 Biopolis Way , Nanos, ,","place":["Singapore, Singapore, 138669"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,9,2]]},"reference":[{"issue":"11","key":"2026091609090055500_cit1","doi-asserted-by":"publisher","first-page":"1633","DOI":"10.1038\/ng.3972","article-title":"The Draft Genome of Tropical Fruit Durian (Durio Zibethinus)","volume":"49","author":"Teh","year":"2017","journal-title":"Nat. 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Dairy Sci."},{"issue":"7","key":"2026091609090055500_cit13","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1093\/chemse\/bjy043","article-title":"Different Olfactory\nPercepts Evoked by Orthonasal and Retronasal Odorant Delivery","volume":"43","author":"Hannum","year":"2018","journal-title":"Chem. Senses"},{"issue":"12","key":"2026091609090055500_cit14","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1111\/j.1365-2044.1989.tb09202.x","article-title":"Oropharyngeal Volumes","volume":"44","author":"Newcombe","year":"1989","journal-title":"Anaesthesia"},{"key":"2026091609090055500_cit15","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1016\/S0167-4501(06)80109-3","article-title":"Phase Ratio Variation Method as an\nEfficient Way to Determine the Partition Coefficients of Various Aroma\nCompounds in Mixture","volume":"43","author":"Savary","year":"2006","journal-title":"Dev. 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