{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T13:17:48Z","timestamp":1783516668626,"version":"3.55.0"},"reference-count":50,"publisher":"American Chemical Society (ACS)","issue":"26","license":[{"start":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T00:00:00Z","timestamp":1782691200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T00:00:00Z","timestamp":1782691200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T00:00:00Z","timestamp":1782691200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100008959","name":"Hunan Agricultural University","doi-asserted-by":"publisher","award":["2019xny-js044"],"award-info":[{"award-number":["2019xny-js044"]}],"id":[{"id":"10.13039\/501100008959","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014472","name":"Scientific Research Foundation of Hunan Provincial Education Department","doi-asserted-by":"publisher","award":["24B0204"],"award-info":[{"award-number":["24B0204"]}],"id":[{"id":"10.13039\/100014472","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32503127"],"award-info":[{"award-number":["32503127"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Agric. Food Chem."],"published-print":{"date-parts":[[2026,7,8]]},"DOI":"10.1021\/acs.jafc.6c05585","type":"journal-article","created":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T09:54:57Z","timestamp":1782726897000},"page":"20674-20688","source":"Crossref","is-referenced-by-count":0,"title":["Chronic Exposure to NaAsO\n                    <sub>2<\/sub>\n                    Induces Renal Fibrosis by Modulating Gut Microbiota-Mediated AhR\/NLRP3 Inflammasome Signaling Pathway"],"prefix":"10.1021","volume":"74","author":[{"given":"Jianyu","family":"Qu","sequence":"first","affiliation":[{"name":"Hunan Engineering Research Center of Livestock and Poultry Health Care, Colleges of Veterinary Medicine","place":["Changsha, China"]},{"name":"Hunan Agricultural University","place":["Changsha, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Fu","sequence":"additional","affiliation":[{"name":"Key Laboratory for Quality Regulation of Livestock and Poultry Products of Hunan Province, College of Animal Science and Technology","place":["Changsha, China"]},{"name":"Hunan Agricultural University","place":["Changsha, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanbin","family":"Wang","sequence":"additional","affiliation":[{"name":"Hunan Engineering Research Center of Livestock and Poultry Health Care, Colleges of Veterinary Medicine","place":["Changsha, China"]},{"name":"Hunan Agricultural University","place":["Changsha, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Jiang","sequence":"additional","affiliation":[{"name":"Hunan Engineering Research Center of Livestock and Poultry Health Care, Colleges of Veterinary Medicine","place":["Changsha, China"]},{"name":"Hunan Agricultural University","place":["Changsha, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Ma","sequence":"additional","affiliation":[{"name":"Hunan Engineering Research Center of Livestock and Poultry Health Care, Colleges of Veterinary Medicine","place":["Changsha, China"]},{"name":"Hunan Agricultural University","place":["Changsha, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jine","family":"Yi","sequence":"additional","affiliation":[{"name":"Hunan Engineering Research Center of Livestock and Poultry Health Care, Colleges of Veterinary Medicine","place":["Changsha, China"]},{"name":"Hunan Agricultural University","place":["Changsha, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9412-4239","authenticated-orcid":true,"given":"Jing","family":"Wu","sequence":"additional","affiliation":[{"name":"Hunan Engineering Research Center of Livestock and Poultry Health Care, Colleges of Veterinary Medicine","place":["Changsha, China"]},{"name":"Hunan Agricultural University","place":["Changsha, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-3048-2521","authenticated-orcid":true,"given":"Yunhuan","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine","place":["Nanjing, China"]},{"name":"Nanjing Agricultural University","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4132-3052","authenticated-orcid":true,"given":"Kehe","family":"Huang","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine","place":["Nanjing, China"]},{"name":"Nanjing Agricultural University","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4185-3563","authenticated-orcid":true,"given":"Ji","family":"Wang","sequence":"additional","affiliation":[{"name":"Hunan Engineering Research Center of Livestock and Poultry Health Care, Colleges of Veterinary Medicine","place":["Changsha, China"]},{"name":"Hunan Agricultural University","place":["Changsha, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihang","family":"Yuan","sequence":"additional","affiliation":[{"name":"Hunan Engineering Research Center of Livestock and Poultry Health Care, Colleges of Veterinary Medicine","place":["Changsha, China"]},{"name":"Hunan Agricultural University","place":["Changsha, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lixin","family":"Wen","sequence":"additional","affiliation":[{"name":"Hunan Engineering Research Center of Livestock and Poultry Health Care, Colleges of Veterinary Medicine","place":["Changsha, China"]},{"name":"Hunan Agricultural University","place":["Changsha, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1543-1512","authenticated-orcid":true,"given":"Shuiping","family":"Liu","sequence":"additional","affiliation":[{"name":"Hunan Engineering Research Center of Livestock and Poultry Health Care, Colleges of Veterinary Medicine","place":["Changsha, China"]},{"name":"Hunan Agricultural University","place":["Changsha, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,6,29]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.154155"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1007\/s11684-011-0158-2"},{"key":"ref3\/cit3","volume-title":"Guidelines for Drinking-Water Quality: Fourth Edition Incorporating the First Addendum","author":"World Health Organization","year":"2017"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jare.2024.01.019"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2026.141087"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2024.135844"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.3c05341"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1002\/imt2.241"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-101921-042929"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-022-00974-4"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-024-02259-3"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202001936"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-024-01913-1"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2021.06.014"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12111931"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.3390\/w14121884"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2022.114370"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1111\/jpi.12812"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.155027"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.202300218"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2025.1703560"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2022.06.025"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2009.06.016"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2023.133038"},{"key":"ref25\/cit25","first-page":"11","volume":"100","author":"IARC Working Group on the Evaluation of Carcinogenic Risks to Humans","year":"2012","journal-title":"IARC Monogr. Eval. Carcinog. Risks Hum."},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-physiol-022516-034227"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.3390\/toxins10070298"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfy172"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1186\/s10020-021-00283-6"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2018.03.016"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1111\/1758-2229.12814"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2024.01.040"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms8040573"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8091424"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-024-01737-3"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10050930"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-020-03645-1"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-01387-y"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.4c04382"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2018.05.003"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.3390\/cells11152296"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2017.07.027"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2022.154546"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202402066"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.3390\/ijms222011265"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.1c05250"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1111\/bph.15062"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms5738"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.13333"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-022-03421-1"}],"container-title":["Journal of Agricultural and Food Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.6c05585","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.6c05585","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T12:43:56Z","timestamp":1783514636000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jafc.6c05585"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,29]]},"references-count":50,"journal-issue":{"issue":"26","published-print":{"date-parts":[[2026,7,8]]}},"alternative-id":["10.1021\/acs.jafc.6c05585"],"URL":"https:\/\/doi.org\/10.1021\/acs.jafc.6c05585","relation":{},"ISSN":["0021-8561","1520-5118"],"issn-type":[{"value":"0021-8561","type":"print"},{"value":"1520-5118","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,29]]}}}