{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:44:45Z","timestamp":1792784685149,"version":"4.5.0"},"reference-count":49,"publisher":"American Chemical Society (ACS)","issue":"41","license":[{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100011710","name":"Shaanxi Provincial Science and Technology Department","doi-asserted-by":"publisher","award":["2023-CX-PT-19"],"award-info":[{"award-number":["2023-CX-PT-19"]}],"id":[{"id":"10.13039\/501100011710","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015401","name":"Key Research and Development Projects of Shaanxi Province","doi-asserted-by":"publisher","award":["2024SF-ZDCYL-03-18"],"award-info":[{"award-number":["2024SF-ZDCYL-03-18"]}],"id":[{"id":"10.13039\/501100015401","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shaanxi Provincial Administration of Traditional Chinese Medicine","award":["SZY-KJCYC-2025-JC-046"],"award-info":[{"award-number":["SZY-KJCYC-2025-JC-046"]}],"id":[{"id":"https:\/\/ror.org\/03x55t826","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Acute liver injury (ALI) has emerged as a significant public health challenge, driving the need for novel therapeutic strategies. While the seeds of Strychnos nux-vomica L. are widely used in traditional clinics, the hepatoprotective potential of its pruning branches remains poorly explored. The crude branch extract relieved obvious hepatic injury, and bioactivity-guided chromatography isolated an undescribed phenolic glycoside from the raw plant material. This monomer boosted cellular antioxidant capability, regulated disrupted lipid metabolism, and adjusted ferroptosis-related changes with the involvement of the Nrf2 signaling pathway. This work supplies a promising natural hepatoprotective candidate and advances sustainable utilization of the plant-branch resources.<\/jats:p>","DOI":"10.1021\/acs.jafc.6c08484","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T06:02:15Z","timestamp":1791784935000},"page":"32346-32356","source":"Crossref","is-referenced-by-count":0,"title":["Unreported Phenolic\nGlycoside from\n                    <i>Strychnos nux-vomica<\/i>\n                    Branches Attenuates Acute Liver\nInjury with the Participation of the Nrf2 Pathway"],"prefix":"10.1021","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6719-6381","authenticated-orcid":true,"given":"Xinxin","family":"Zhang","sequence":"first","affiliation":[{"name":"Xi\u2019an Jiaotong University , 99 Yanxiang Road, Xixian New Area , , ,","place":["Xi\u2019an, Shaanxi, China, 710115"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saisai","family":"Xin","sequence":"additional","affiliation":[{"name":"Xi\u2019an Jiaotong University , 99 Yanxiang Road, Xixian New Area , , ,","place":["Xi\u2019an, Shaanxi, China, 710115"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumeng","family":"Yan","sequence":"additional","affiliation":[{"name":"Xi\u2019an Jiaotong University , 99 Yanxiang Road, Xixian New Area , , ,","place":["Xi\u2019an, Shaanxi, China, 710115"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojie","family":"Shi","sequence":"additional","affiliation":[{"name":"Xi\u2019an Jiaotong University , 99 Yanxiang Road, Xixian New Area , , ,","place":["Xi\u2019an, Shaanxi, China, 710115"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shufei","family":"Cui","sequence":"additional","affiliation":[{"name":"Xi\u2019an Jiaotong University , 99 Yanxiang Road, Xixian New Area , , ,","place":["Xi\u2019an, Shaanxi, China, 710115"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanli","family":"Yang","sequence":"additional","affiliation":[{"name":"Xi\u2019an Jiaotong University , 99 Yanxiang Road, Xixian New Area , , ,","place":["Xi\u2019an, Shaanxi, China, 710115"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Zhang","sequence":"additional","affiliation":[{"name":"Xi\u2019an Jiaotong University , 99 Yanxiang Road, Xixian New Area , , ,","place":["Xi\u2019an, Shaanxi, China, 710115"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianwei","family":"Dou","sequence":"additional","affiliation":[{"name":"Xi\u2019an Jiaotong University , 99 Yanxiang Road, Xixian New Area , , ,","place":["Xi\u2019an, Shaanxi, China, 710115"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Xi\u2019an Medical University , No.1 Xinwang Road , , ,","place":["Xi\u2019an, Shaanxi, China, 710021"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zengjun","family":"Guo","sequence":"additional","affiliation":[{"name":"Xi\u2019an Jiaotong University , 99 Yanxiang Road, Xixian New Area , , ,","place":["Xi\u2019an, Shaanxi, China, 710115"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,10,12]]},"reference":[{"issue":"17","key":"2026102109082328000_cit1","doi-asserted-by":"publisher","first-page":"11515","DOI":"10.1021\/acs.jafc.5c01868","article-title":"Consistency of phenolic compounds\nin plant residues parts: A review of primary sources, key compounds,\nand extraction trends","volume":"73","author":"Strieder","year":"2025","journal-title":"J. Agric. Food Chem."},{"key":"2026102109082328000_cit2","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1021\/np9703454","article-title":"Strychnochrysine, a new bisindole\nalkaloid from the\nroots of Strychnos nux-vomica","volume":"61","author":"Biala","year":"1998","journal-title":"J. Nat. Prod."},{"key":"2026102109082328000_cit3","doi-asserted-by":"publisher","first-page":"1987","DOI":"10.1021\/np300339r","article-title":"Strynoxlines A and\nB, alkaloids with an unprecedented carbon skeleton from Strychnos nux-vomica","volume":"75","author":"Fu","year":"2012","journal-title":"J. Nat.\nProd."},{"key":"2026102109082328000_cit4","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2025.1675432","article-title":"Multi-omics\nintegration reveals organ-specific biosynthesis of flavonoids and\nterpenoids in the medicinal plant Bidens alba","volume":"16","author":"Wang","year":"2025","journal-title":"Front. Plant Sci."},{"issue":"10","key":"2026102109082328000_cit5","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1097\/MCG.0000000000001409","article-title":"Real world comorbidity burden, health\ncare utilization,\nand costs of nonalcoholic steatohepatitis patients with advanced liver\ndiseases","volume":"55","author":"Wong","year":"2021","journal-title":"J. Clin. Gastroenterol."},{"key":"2026102109082328000_cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2025.156941","article-title":"Ginsenoside\nRg5 ameliorates lipopolysaccharide (LPS)-induced acute\nliver injury via interfering Autophagy\/Nrf2\/Ferroptosis signal axis","volume":"144","author":"Shan","year":"2025","journal-title":"Phytomedicine"},{"issue":"7230","key":"2026102109082328000_cit7","doi-asserted-by":"publisher","first-page":"726","DOI":"10.1038\/nature07583","article-title":"Signalling\nthrough\nRHEB-1 mediates intermittent fasting-induced longevity in C. elegans","volume":"457","author":"Honjoh","year":"2009","journal-title":"Nature"},{"key":"2026102109082328000_cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2024.118135","article-title":"Bioactive compound\nschaftoside from Clinacanthus nutans attenuates acute liver injury by inhibiting ferroptosis through\nactivation the Nrf2\/GPX4 pathway","volume":"328","author":"Yu","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"2026102109082328000_cit9","doi-asserted-by":"publisher","first-page":"1884","DOI":"10.1039\/D2FO02716J","article-title":"Kaempferol\nprevents acetaminophen-induced liver injury by suppressing hepatocyte\nferroptosis via Nrf2 pathway activation","volume":"14","author":"Li","year":"2023","journal-title":"Food\nFunct."},{"key":"2026102109082328000_cit10","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2025.1582435","article-title":"Langqing Meiduo Jiujie\npills treatment attenuates acute liver injury in animals by regulating\nanti-oxidative stress and liver metabolism","volume":"16","author":"Wang","year":"2025","journal-title":"Front. Pharmacol."},{"key":"2026102109082328000_cit11","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1016\/j.freeradbiomed.2024.08.038","article-title":"Caffeic acid ameliorates\nmetabolic dysfunction-associated steatotic liver disease via alleviating\noxidative damage and lipid accumulation in hepatocytes through activating\nNrf2 via targeting Keap1","volume":"224","author":"Zhang","year":"2024","journal-title":"Free Radical Biol.\nMed."},{"key":"2026102109082328000_cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2023.115717","article-title":"Melatonin alleviates\nparticulate matter-induced liver fibrosis by inhibiting ROS-mediated\nmitophagy and inflammation via Nrf2 activation","volume":"268","author":"Zhu","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"2026102109082328000_cit13","doi-asserted-by":"publisher","first-page":"11041","DOI":"10.2147\/JIR.S498775","article-title":"Maresin1\ninhibits ferroptosis via the Nrf2\/SLC7A11\/GPX4 pathway to protect\nagainst sepsis-induced acute liver injury","volume":"17","author":"Guo","year":"2024","journal-title":"J.\nInflammation Res."},{"key":"2026102109082328000_cit14","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.freeradbiomed.2018.09.043","article-title":"The development of the concept of ferroptosis","volume":"133","author":"Hirschhorn","year":"2019","journal-title":"Free Radical Biol. Med."},{"key":"2026102109082328000_cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2021.113869","article-title":"Pathophysiological\ncommunication between hepatocytes and non-parenchymal cells in liver\ninjury from NAFLD to liver fibrosis","volume":"176","author":"Kumar","year":"2021","journal-title":"Adv. Drug\nDelivery Rev."},{"issue":"3","key":"2026102109082328000_cit16","doi-asserted-by":"publisher","DOI":"10.1097\/HC9.0000000000000658","article-title":"A novel KEAP1 inhibitor, tiliroside, activates NRF2 to protect against\nacetaminophen-induced oxidative stress and acute liver injury","volume":"9","author":"Cai","year":"2025","journal-title":"Hepatol. Commun."},{"issue":"2","key":"2026102109082328000_cit17","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1080\/15548627.2022.2062112","article-title":"Acetylation in the regulation of\nautophagy","volume":"19","author":"Xu","year":"2023","journal-title":"Autophagy"},{"issue":"11","key":"2026102109082328000_cit18","doi-asserted-by":"publisher","DOI":"10.3390\/biom12111652","article-title":"Spatial\nanalysis of NQO1 in non-small cell lung cancer shows its expression\nis independent of NRF1 and NRF2 in the tumor microenvironment","volume":"12","author":"Kaghazchi","year":"2022","journal-title":"Biomolecules"},{"issue":"9","key":"2026102109082328000_cit19","doi-asserted-by":"publisher","DOI":"10.3390\/antiox13091098","article-title":"Carthamus tinctorius L. (Safflower)\nflower extract attenuates hepatic injury and steatosis in a rat model\nof type 2 diabetes mellitus via Nrf2-dependent hypoglycemic, antioxidant,\nand hypolipidemic effects","volume":"13","author":"Alshareef","year":"2024","journal-title":"Antioxidants"},{"key":"2026102109082328000_cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2026.107416","article-title":"Monoterpene indole\nalkaloids from the seeds of Strychnos nux-vomica L. with anti-rheumatoid arthritis\nactivity","volume":"193","author":"Zhang","year":"2026","journal-title":"Fitoterapia"},{"key":"2026102109082328000_cit21","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2022.1098954","article-title":"Red-fleshed\napple flavonoid extract\nalleviates CCl4-induced liver injury in mice","volume":"9","author":"Chen","year":"2022","journal-title":"Front. Nutr."},{"key":"2026102109082328000_cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2020.173244","article-title":"Berbamine\ninduced AMPK activation regulates mTOR\/SREBP-1c axis and Nrf2\/ARE\npathway to allay lipid accumulation and oxidative stress in steatotic\nHepG2 cells","volume":"882","author":"Sharma","year":"2020","journal-title":"Eur. J. Pharmacol."},{"key":"2026102109082328000_cit23","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2026.1735481","article-title":"Acetylshikonin mitigates\ndiet-induced MASLD by targeting PPAR\u03b3-mediated metabolic dysfunction","volume":"17","author":"Ou","year":"2026","journal-title":"Front. Pharmacol."},{"issue":"5","key":"2026102109082328000_cit24","doi-asserted-by":"publisher","first-page":"2351","DOI":"10.7150\/thno.70692","article-title":"SNX10-mediated\ndegradation of LAMP2A by NSAIDs inhibits chaperone-mediated autophagy\nand induces hepatic lipid accumulation","volume":"12","author":"Lee","year":"2022","journal-title":"Theranostics"},{"issue":"267","key":"2026102109082328000_cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2023.115625","article-title":"Perfluorooctane\nsulfonate (PFOS), a novel environmental\npollutant, induces liver injury in mice by activating hepatocyte ferroptosis","volume":"15","author":"Yang","year":"2023","journal-title":"Environmen. Toxicol."},{"key":"2026102109082328000_cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2026.121659","article-title":"Xin Jia congrong\ntusizi decoction\nreverses ferroptosis in granulosa cells to rescue ovarian function\ndecline via p53\/Nrf2\/SLC7A11\/GPX4 signaling pathway","volume":"367","author":"Liu","year":"2026","journal-title":"J. Ethnopharmacol."},{"key":"2026102109082328000_cit27","volume-title":"Pharmacopoeia of the People\u2019s Republic of China (2025-ed)","author":"Chinese Pharmacopoeia Commission.","year":"2025"},{"issue":"7","key":"2026102109082328000_cit28","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1021\/acschemneuro.2c00797","article-title":"Anti-strychnine\nimmunoconjugate reduces the effects of strychnine-induced toxicity\nin mice","volume":"14","author":"Baehr","year":"2023","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"2026102109082328000_cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2025.103949","article-title":"\u03b2-Hydroxybutyrate\nameliorates lipopolysaccharide-induced liver injury through \u03b2-hydroxybutyrylation of the SOD2 protein in mice","volume":"88","author":"Bai","year":"2025","journal-title":"Redox Biol."},{"key":"2026102109082328000_cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2025.103557","article-title":"Quercetin\nalleviates LPS\/iE-DAP-induced liver injury by suppressing ferroptosis\nvia regulating ferritinophagy and intracellular iron efflux","volume":"81","author":"Zhang","year":"2025","journal-title":"Redox Biol."},{"issue":"8","key":"2026102109082328000_cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.crfs.2024.100699","article-title":"Glucosamine attenuates alcohol-induced\nacute liver\ninjury via inhibiting oxidative stress and inflammation","volume":"8","author":"Lai","year":"2024","journal-title":"Curr. Res. Food Sci."},{"key":"2026102109082328000_cit32","doi-asserted-by":"publisher","first-page":"3288","DOI":"10.1016\/j.tet.2012.03.006","article-title":"New alkaloids from the seeds of Strychnos nux-vomica","volume":"68","author":"Zhao","year":"2012","journal-title":"Tetrahedron"},{"issue":"2","key":"2026102109082328000_cit33","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1515\/reveh-2020-0048","article-title":"Toxicity of\ncarbon tetrachloride,\nfree radicals and role of antioxidants","volume":"36","author":"Unsal","year":"2021","journal-title":"Rev.\nEnviron. Health"},{"issue":"3","key":"2026102109082328000_cit34","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1002\/hep.24755","article-title":"Addition of simvastatin to cold storage solution prevents endothelial\ndysfunction in explanted rat livers","volume":"55","author":"Russo","year":"2012","journal-title":"Hepatology"},{"issue":"5","key":"2026102109082328000_cit35","doi-asserted-by":"publisher","first-page":"1564","DOI":"10.1053\/j.gastro.2018.07.022","article-title":"Simvastatin prevents progression of acute on chronic\nliver failure in rats with cirrhosis and portal hypertension","volume":"155","author":"Tripathi","year":"2018","journal-title":"Gastroenterology"},{"issue":"3","key":"2026102109082328000_cit36","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1016\/S0031-6997(25)07129-7","article-title":"Carbon\ntetrachloride hepatotoxicity","volume":"19","author":"Recknagel","year":"1967","journal-title":"Pharmacol. Rev."},{"issue":"2","key":"2026102109082328000_cit37","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1080\/713611034","article-title":"Hepatotoxicity\nand mechanism of action\nof haloalkanes: carbon tetrachloride as a toxicological model","volume":"33","author":"Weber","year":"2003","journal-title":"Crit. Rev. Toxicol."},{"issue":"2\u20133","key":"2026102109082328000_cit38","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1016\/j.tox.2006.09.019","article-title":"A temporal study on\nthe histopathological, biochemical and molecular\nresponses of CCl4-induced hepatotoxicity in Cyp2e1-null\nmice","volume":"228","author":"Avasarala","year":"2006","journal-title":"Toxicology"},{"issue":"1","key":"2026102109082328000_cit39","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-026-04321-5","article-title":"Preventive\neffects and mechanisms of yam exosome-like nanoparticles on acute\nliver injury","volume":"24","author":"Yao","year":"2026","journal-title":"J. Nanobiotechnol."},{"key":"2026102109082328000_cit40","doi-asserted-by":"publisher","first-page":"12208","DOI":"10.1021\/acs.jafc.9b05495","article-title":"Apple polyphenol extract alleviates\nhigh-fat-diet-induced hepatic steatosis in male C57BL\/6 mice by targeting\nLKB1\/AMPK pathway","volume":"67","author":"Li","year":"2019","journal-title":"J. Agric. Food Chem."},{"key":"2026102109082328000_cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2025.157276","article-title":"Grifolin-4-l-ergothioneine\nfrom Albatrellus dispansus ameliorates CCl4-induced liver\ninjury via activating SIRT1\/AMPK\/NRF2 signaling in hepatocytes","volume":"148","author":"Li","year":"2025","journal-title":"Phytomedicine"},{"issue":"3","key":"2026102109082328000_cit42","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1007\/BF02628465","article-title":"Further cellular\ninvestigation of the human hepatoblastoma-derived cell line HepG2:\nMorphology and immunocytochemical studies of hepatic-secreted proteins","volume":"25","author":"Bouma","year":"1989","journal-title":"In Vitro Cell. Dev. Biol."},{"key":"2026102109082328000_cit43","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202521818","article-title":"Artesunate\nameliorates APAP-induced liver injury by promoting NEDD4L-mediated\nubiquitination and degradation of TXNIP","volume":"13","author":"Zhang","year":"2026","journal-title":"Adv.\nSci."},{"key":"2026102109082328000_cit44","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1016\/j.freeradbiomed.2025.11.005","article-title":"Ammonium tetrathiomolybdate\nameliorates heat stroke-induced murine liver injury by activating\nthe Nrf2\/HO-1 signaling pathway and inhibiting oxidative stress","volume":"242","author":"Jiang","year":"2026","journal-title":"Free Radical Biol. Med."},{"key":"2026102109082328000_cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2025.120998","article-title":"Prophylactic\nisoimperatorin protects against LPS-ALI via mTOR-dependent control\nof inflammation, oxidative stress and ferroptosis markers","volume":"358","author":"Zhang","year":"2026","journal-title":"J. Ethnopharmacol."},{"issue":"7","key":"2026102109082328000_cit46","doi-asserted-by":"publisher","DOI":"10.3390\/md23070287","article-title":"Rosmarinic acid\nprotects against acetaminophen-induced hepatotoxicity\nby suppressing ferroptosis and oxidative stress through Nrf2\/HO-1\nactivation in mice","volume":"23","author":"Wu","year":"2025","journal-title":"Mar. Drugs"},{"issue":"1","key":"2026102109082328000_cit47","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1002\/tox.24412","article-title":"Resveratrol\nalleviated T-2 toxin-induced liver injury\nvia preservation of Nrf2 pathway and GSH synthesis","volume":"40","author":"Jin","year":"2025","journal-title":"Environmen. Toxicol."},{"key":"2026102109082328000_cit48","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1002\/iub.1409","article-title":"Curcumin attenuates ethanol-induced\nhepatic steatosis through modulating Nrf2\/FXR signaling in hepatocytes","volume":"67","author":"Lu","year":"2015","journal-title":"IUBMB Life"},{"key":"2026102109082328000_cit49","doi-asserted-by":"publisher","first-page":"1060","DOI":"10.1016\/j.cell.2012.03.042","article-title":"Ferroptosis:\nan iron-dependent form of nonapoptotic cell death","volume":"149","author":"Dixon","year":"2012","journal-title":"Cell"}],"container-title":["Journal of Agricultural\nand Food Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.6c08484","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/jafcau\/article-pdf\/doi\/10.1021\/acs.jafc.6c08484\/68813947\/acs.jafc.6c08484.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/jafcau\/article-pdf\/doi\/10.1021\/acs.jafc.6c08484\/68813947\/acs.jafc.6c08484.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T13:30:36Z","timestamp":1792589436000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/jafcau\/article\/74\/41\/32346\/5448653\/Unreported-Phenolic-Glycoside-from-Strychnos-nux"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,12]]},"references-count":49,"journal-issue":{"issue":"41","published-online":{"date-parts":[[2026,10,12]]},"published-print":{"date-parts":[[2026,10,21]]}},"URL":"https:\/\/doi.org\/10.1021\/acs.jafc.6c08484","relation":{},"ISSN":["0021-8561","1520-5118"],"issn-type":[{"value":"0021-8561","type":"print"},{"value":"1520-5118","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,12]]}}}