{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T15:55:38Z","timestamp":1791388538912,"version":"4.3.3"},"reference-count":48,"publisher":"American Chemical Society (ACS)","issue":"39","license":[{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100011791","name":"Jiangsu Provincial Department of Finance","doi-asserted-by":"publisher","award":["BF2025318"],"award-info":[{"award-number":["BF2025318"]}],"id":[{"id":"10.13039\/501100011791","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFD210070202"],"award-info":[{"award-number":["2023YFD210070202"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008868","name":"Jiangsu Provincial Department of Science and Technology","doi-asserted-by":"publisher","award":["BF2025318"],"award-info":[{"award-number":["BF2025318"]}],"id":[{"id":"10.13039\/501100008868","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>CaSR has been recognized as a potential receptor involved in kokumi peptide perception. However, the molecular basis underlying kokumi-peptide-induced cellular responses remains insufficiently understood. Herein, CaSR-associated responses induced by kokumi peptides were investigated in STC-1 cells. Compared with MSG stimulation alone, MSG combined with \u03b3-glutamyl peptides enhanced intracellular Ca2+ mobilization and CCK secretion, with response trends consistent with sensory evaluation. MSG+\u03b3E\u03b3EV elicited the strongest cellular response, increasing CCK secretion from 31.38 \u00b1 3.18 pg\/mL in the MSG group to 60.84 \u00b1 4.45 pg\/mL, while Ca2+ fluorescence intensity increased by 133.60% relative to MSG treatment alone (p &amp;lt; 0.05). Pretreatment with the CaSR antagonist NPS-2143 reduced MSG+\u03b3E\u03b3EV-induced Ca2+ mobilization and CCK secretion by 51.09 and 42.90%, respectively, supporting the involvement of CaSR in these cellular responses. Metabolomic and transcriptomic analyses revealed alterations in signaling-associated metabolites and pathways, including calcium signaling, MAPK signaling, PI3K-Akt signaling, cAMP signaling, phosphoinositide-related metabolism, and glycerophospholipid metabolism. These findings suggest that signaling responses associated with CaSR involvement in STC-1 cells share certain features with taste-related signal transduction processes. Collectively, the results provide insights into kokumi-peptide-induced cellular responses and their potential relevance to umami enhancement.<\/jats:p>","DOI":"10.1021\/acs.jafc.6c11250","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T14:01:59Z","timestamp":1790258519000},"page":"31060-31079","source":"Crossref","is-referenced-by-count":0,"title":["Umami-Enhancing\nEffects of Kokumi Peptides Associated\nwith CaSR-Related Cellular Responses in STC-1 Cells"],"prefix":"10.1021","volume":"74","author":[{"given":"Peng","family":"Deng","sequence":"first","affiliation":[{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]},{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Chen","sequence":"additional","affiliation":[{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]},{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Shen","sequence":"additional","affiliation":[{"name":"Xinjiang Agricultural University , , ,","place":["Urumqi, China, 830052"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0780-1199","authenticated-orcid":true,"given":"Qiuming","family":"Chen","sequence":"additional","affiliation":[{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]},{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaojun","family":"Wang","sequence":"additional","affiliation":[{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]},{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3917-1686","authenticated-orcid":true,"given":"Zhiyong","family":"He","sequence":"additional","affiliation":[{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]},{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Chen","sequence":"additional","affiliation":[{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]},{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9259-1992","authenticated-orcid":true,"given":"Maomao","family":"Zeng","sequence":"additional","affiliation":[{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]},{"name":"Jiangnan University , , ,","place":["Wuxi, China, 214122"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,9,24]]},"reference":[{"key":"2026100711073389500_cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2025.117443","article-title":"Novel umami peptides from Takifugu rubripes and evaluation of their\numami perception through virtual screening and biolayer interferometry","volume":"221","author":"Guo","year":"2025","journal-title":"Food Res. Int."},{"key":"2026100711073389500_cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2025.143621","article-title":"Identification and\ntaste presentation characteristics of umami peptides\nfrom soybean paste based on peptidomics and virtual screening","volume":"477","author":"Pan","year":"2025","journal-title":"Food Chem."},{"key":"2026100711073389500_cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2025.117331","article-title":"Umami peptide synergy\nunveiled: A comprehensive study from molecular simulation to practical\nvalidation of sensing strategy","volume":"278","author":"Yu","year":"2025","journal-title":"Biosens. Bioelectron."},{"issue":"6877","key":"2026100711073389500_cit4","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1038\/nature726","article-title":"An amino-acid taste receptor","volume":"416","author":"Nelson","year":"2002","journal-title":"Nature"},{"issue":"3","key":"2026100711073389500_cit5","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/S0092-8674(03)00844-4","article-title":"The receptors for\nmammalian sweet and umami taste","volume":"115","author":"Zhao","year":"2003","journal-title":"Cell"},{"key":"2026100711073389500_cit6","doi-asserted-by":"publisher","first-page":"15160","DOI":"10.1073\/pnas.2334159100","article-title":"Intracellular\nCa2+ and the phospholipid PIP2 regulate\nthe taste transduction ion channel TRPM5","volume":"100","author":"Liu","year":"2003","journal-title":"Proc.\nNatl. Acad. Sci. U. S. A."},{"key":"2026100711073389500_cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2024.139910","article-title":"Enzymatic synthesis and sensory evaluation\nof the novel kokumi compound N-butyryl phenylalanine","volume":"455","author":"Cai","year":"2024","journal-title":"Food Chem."},{"issue":"45","key":"2026100711073389500_cit8","doi-asserted-by":"publisher","first-page":"17235","DOI":"10.1021\/acs.jafc.3c03239","article-title":"Preparation\nand kokumi properties of N-acetyl-Val\/Leu\/Ile\/Met\/Phe\nin the presence of acetic acid and amino acid: A commercially available\ntransglutaminase and protease A2SD","volume":"71","author":"Lin","year":"2023","journal-title":"J. Agric.\nFood Chem."},{"key":"2026100711073389500_cit9","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1016\/j.tifs.2019.07.022","article-title":"Gamma glutamyl peptides: The food\nsource, enzymatic synthesis, kokumi-active and the potential functional\nproperties \u2013 A review","volume":"91","author":"Yang","year":"2019","journal-title":"Trends Food Sci.\nTechnol."},{"issue":"45","key":"2026100711073389500_cit10","doi-asserted-by":"publisher","first-page":"14395","DOI":"10.1021\/acs.jafc.2c04919","article-title":"Synergistic effect of kokumi-active \u03b3-glutamyl\npeptides and L-glutamate on enhancing umami sensation and stimulating\ncholecystokinin secretion via T1R1\/T1R3 activation in STC-1 cells","volume":"70","author":"Yang","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"2026100711073389500_cit11","doi-asserted-by":"publisher","first-page":"1016","DOI":"10.1074\/jbc.M109.029165","article-title":"Involvement\nof the calcium-sensing receptor in human taste perception","volume":"285","author":"Ohsu","year":"2010","journal-title":"J. Biol. Chem."},{"issue":"4","key":"2026100711073389500_cit12","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0034489","article-title":"Kokumi substances,\nenhancers of basic tastes, induce responses in calcium-sensing receptor\nexpressing taste cells","volume":"7","author":"Maruyama","year":"2012","journal-title":"PLoS One"},{"key":"2026100711073389500_cit13","doi-asserted-by":"publisher","DOI":"10.1186\/2044-7248-4-11","article-title":"Mechanism of the perception\nof \u201ckokumi\u201d substances and the sensory\ncharacteristics of the \u201ckokumi\u201d peptide,\n\u03b3-Glu-Val-Gly","volume":"4","author":"Kuroda","year":"2015","journal-title":"Flavour"},{"key":"2026100711073389500_cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2025.118024","article-title":"Unlocking the potential\nof umami peptides: A comprehensive review of preparation methods,\nevaluation strategies, health benefits, and taste transduction mechanisms","volume":"225","author":"Zhao","year":"2026","journal-title":"Food Res. Int."},{"issue":"2","key":"2026100711073389500_cit15","doi-asserted-by":"publisher","first-page":"1462","DOI":"10.1111\/1541-4337.12916","article-title":"Research progress in the screening\nand evaluation of\numami peptides","volume":"21","author":"Qi","year":"2022","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"2026100711073389500_cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2026.118641","article-title":"Preparation,\nisolation, purification\nand identification of umami peptides with functional effects: a review","volume":"231","author":"Hao","year":"2026","journal-title":"Food Res. Int."},{"key":"2026100711073389500_cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2024.139691","article-title":"Unraveling novel umami peptides from\nyeast extract (Saccharomyces cerevisiae) using peptidomics and molecular interaction modeling","volume":"453","author":"Gao","year":"2024","journal-title":"Food Chem."},{"key":"2026100711073389500_cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2023.137386","article-title":"Virtual screening and\ncharacteristics of novel umami\npeptides from porcine type I collagen","volume":"434","author":"Gu","year":"2024","journal-title":"Food\nchem."},{"issue":"5","key":"2026100711073389500_cit19","doi-asserted-by":"publisher","DOI":"10.3390\/chemosensors13050161","article-title":"A systematic review\nof the applications of electronic nose and electronic tongue in food\nquality assessment and safety","volume":"13","author":"Vanaraj","year":"2025","journal-title":"Chemosensors"},{"key":"2026100711073389500_cit20","doi-asserted-by":"publisher","first-page":"3001","DOI":"10.1109\/JSEN.2013.2263125","article-title":"Electronic tongues\u2013a\nreview","volume":"13","author":"Tahara","year":"2013","journal-title":"IEEE Sens.\nJ."},{"key":"2026100711073389500_cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2019.111923","article-title":"Bioelectronic tongue: Current status\nand perspectives","volume":"150","author":"Wasilewski","year":"2020","journal-title":"Biosens. Bioelectron."},{"issue":"7","key":"2026100711073389500_cit22","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202206101","article-title":"Mimicking the biological\nsense of\ntaste in vitro using a taste organoids-on-a-chip\nsystem","volume":"10","author":"Wu","year":"2023","journal-title":"Adv. Sci."},{"issue":"9","key":"2026100711073389500_cit23","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202511309","article-title":"Correlative imaging platform linking\ntaste cell function to molecular\nidentity","volume":"13","author":"Lee","year":"2026","journal-title":"Adv. Sci."},{"issue":"8","key":"2026100711073389500_cit24","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1038\/nrn.2017.68","article-title":"Taste buds: cells, signals and synapses","volume":"18","author":"Roper","year":"2017","journal-title":"Nat. Rev. Neurosci."},{"issue":"18","key":"2026100711073389500_cit25","doi-asserted-by":"publisher","first-page":"1699","DOI":"10.1056\/NEJMra2304578","article-title":"Physiological\nintegration of taste and metabolism","volume":"390","author":"Egan","year":"2024","journal-title":"N. Engl.\nJ. Med."},{"key":"2026100711073389500_cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2024.139466","article-title":"Gamma-glutamylation of beef protein hydrolysates to improve its overall\ntaste and functions of gastro-intestinal hormone (CCK and GLP-1) pro-secretion\nand anti-inflammation","volume":"452","author":"Chen","year":"2024","journal-title":"Food Chem."},{"issue":"1","key":"2026100711073389500_cit27","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.bios.2012.02.028","article-title":"Sweet and\nbitter tastants specific\ndetection by the taste cell-based sensor","volume":"35","author":"Hui","year":"2012","journal-title":"Biosens.\nBioelectron."},{"key":"2026100711073389500_cit28","doi-asserted-by":"publisher","first-page":"768","DOI":"10.1016\/j.foodchem.2016.06.016","article-title":"Sweetness-induced\nactivation of membrane\ndipole potential in STC-1 taste cells","volume":"212","author":"Chen","year":"2016","journal-title":"Food\nChem."},{"issue":"12","key":"2026100711073389500_cit29","doi-asserted-by":"publisher","DOI":"10.1002\/bmc.4369","article-title":"Establishment and application of\na method for screening the therapeutic drugs of ethanol-induced liver\ninjury based on cellular metabonomics","volume":"32","author":"Zhang","year":"2018","journal-title":"Biomed.\nChromatogr."},{"key":"2026100711073389500_cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2024.114534","article-title":"Insights into\nthe identification of bitter peptides from Jinhua ham and its taste\nmechanism by molecular docking and transcriptomics analysis","volume":"189","author":"Dai","year":"2024","journal-title":"Food Res. Int."},{"issue":"38","key":"2026100711073389500_cit31","doi-asserted-by":"publisher","first-page":"14046","DOI":"10.1021\/acs.jafc.3c02454","article-title":"Identification and characterization\nof novel umami peptides from\nprotein hydrolysates of Morchella esculenta and their\ninteraction with T1R1\/T1R3 receptor","volume":"71","author":"Wang","year":"2023","journal-title":"J. Agric.\nFood Chem."},{"key":"2026100711073389500_cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2024.141569","article-title":"Targeted discovery\nof pea protein-derived GLP-1-secreting peptides by CaSR activation-based\nmolecular docking and their digestive stability","volume":"464","author":"Zhang","year":"2025","journal-title":"Food Chem."},{"issue":"4","key":"2026100711073389500_cit33","doi-asserted-by":"publisher","first-page":"2392","DOI":"10.1073\/pnas.042617699","article-title":"Expression of bitter taste receptors of the T2R family\nin the gastrointestinal tract and enteroendocrine STC-1 cells","volume":"99","author":"Wu","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"7","key":"2026100711073389500_cit34","doi-asserted-by":"publisher","first-page":"4071","DOI":"10.1039\/C9FO00313D","article-title":"\u03b3-[Glu](n\u00a0=\u00a01,2)-Phe\/-Met\/-Val\nstimulates gastrointestinal\nhormone (CCK and GLP-1) secretion by activating the calcium-sensing\nreceptor","volume":"10","author":"Yang","year":"2019","journal-title":"Food Funct."},{"key":"2026100711073389500_cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2020.109717","article-title":"GPCR mediated control\nof calcium dynamics: A systems perspective","volume":"74","author":"Dhyani","year":"2020","journal-title":"Cell. Signalling"},{"key":"2026100711073389500_cit36","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-67844-3","article-title":"Analyzing\nkinetic signaling data for G-protein-coupled receptors","volume":"10","author":"Hoare","year":"2020","journal-title":"Sci. Rep."},{"issue":"18","key":"2026100711073389500_cit37","doi-asserted-by":"publisher","first-page":"1991","DOI":"10.1097\/WNR.0b013e3282f242d3","article-title":"Intestinal\nSTC-1 cells respond to\nfive basic taste stimuli","volume":"18","author":"Saitoh","year":"2007","journal-title":"NeuroReport"},{"key":"2026100711073389500_cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2022.134225","article-title":"Food peptides as inducers\nof CCK and GLP-1 secretion and GPCRs involved in enteroendocrine cell\nsignalling","volume":"402","author":"Santos-Herna\u0301ndez","year":"2023","journal-title":"Food Chem."},{"issue":"2","key":"2026100711073389500_cit39","doi-asserted-by":"publisher","first-page":"171","DOI":"10.2220\/biomedres.35.171","article-title":"Effect of five taste\nligands on the release of CCK from an enteroendocrine cell line, STC-1","volume":"35","author":"Miyata","year":"2014","journal-title":"Biomed. Res."},{"issue":"3","key":"2026100711073389500_cit40","doi-asserted-by":"publisher","first-page":"G271","DOI":"10.1152\/ajpgi.00074.2012","article-title":"Sensing of amino acids by the gut-expressed\ntaste receptor\nT1R1-T1R3 stimulates CCK secretion","volume":"304","author":"Daly","year":"2013","journal-title":"Am. J. Physiol.\nGastrointest. Liver Physiol."},{"key":"2026100711073389500_cit41","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1111\/j.1748-1716.2011.02308.x","article-title":"Taste receptor\nsignalling - from tongues to lungs","volume":"204","author":"Kinnamon","year":"2012","journal-title":"Acta Physiol."},{"key":"2026100711073389500_cit42","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1111\/j.1749-6632.2009.04106.x","article-title":"Receptors\nand transduction of umami taste stimuli","volume":"1170","author":"Kinnamon","year":"2009","journal-title":"Ann.\nN. Y. Acad. Sci."},{"issue":"8","key":"2026100711073389500_cit43","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1008925","article-title":"A subset of broadly\nresponsive Type III taste cells contribute to the detection of bitter,\nsweet and umami stimuli","volume":"16","author":"Dutta Banik","year":"2020","journal-title":"PLoS Genet."},{"issue":"6","key":"2026100711073389500_cit44","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0098777","article-title":"Calcium sensing receptor\nmodulates extracellular calcium entry and\nproliferation via TRPC3\/6 channels in cultured human mesangial cells","volume":"9","author":"Meng","year":"2014","journal-title":"PLoS One"},{"issue":"8001","key":"2026100711073389500_cit45","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1038\/s41586-024-07055-2","article-title":"Allosteric modulation and G-protein selectivity of\nthe Ca2+-sensing receptor","volume":"626","author":"He","year":"2024","journal-title":"Nature"},{"issue":"1","key":"2026100711073389500_cit46","doi-asserted-by":"publisher","first-page":"R1","DOI":"10.1530\/JME-18-0049","article-title":"Insights\ninto calcium-sensing receptor trafficking and biased signalling by\nstudies of calcium homeostasis","volume":"61","author":"Gorvin","year":"2018","journal-title":"J. Mol. Endocrinol."},{"issue":"4","key":"2026100711073389500_cit47","doi-asserted-by":"publisher","first-page":"1054","DOI":"10.1016\/j.celrep.2017.12.089","article-title":"AP2\u03c3 mutations\nimpair calcium-sensing receptor trafficking and signaling, and show\nan endosomal pathway to spatially direct G-protein selectivity","volume":"22","author":"Gorvin","year":"2018","journal-title":"Cell Rep."},{"issue":"17","key":"2026100711073389500_cit48","doi-asserted-by":"publisher","first-page":"12970","DOI":"10.1074\/jbc.275.17.12970","article-title":"Integrins\nregulate the linkage between\nupstream and downstream events in G protein-coupled receptor signaling\nto mitogen-activated protein kinase","volume":"275","author":"Short","year":"2000","journal-title":"J. Biol.\nChem."}],"container-title":["Journal of Agricultural\nand Food Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.6c11250","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/jafcau\/article-pdf\/74\/39\/31060\/68640317\/acs.jafc.6c11250.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/jafcau\/article-pdf\/74\/39\/31060\/68640317\/acs.jafc.6c11250.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T15:31:10Z","timestamp":1791387070000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/jafcau\/article\/74\/39\/31060\/5437766\/Umami-Enhancing-Effects-of-Kokumi-Peptides"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,24]]},"references-count":48,"journal-issue":{"issue":"39","published-online":{"date-parts":[[2026,9,24]]},"published-print":{"date-parts":[[2026,10,7]]}},"URL":"https:\/\/doi.org\/10.1021\/acs.jafc.6c11250","relation":{},"ISSN":["0021-8561","1520-5118"],"issn-type":[{"value":"0021-8561","type":"print"},{"value":"1520-5118","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,24]]}}}