{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:41:46Z","timestamp":1785544906035,"version":"3.56.0"},"reference-count":58,"publisher":"American Chemical Society (ACS)","issue":"4","funder":[{"DOI":"10.13039\/501100006196","name":"Oulun Yliopisto","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002341","name":"Suomen Akatemia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002341","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Agric. Food Chem."],"published-print":{"date-parts":[[2019,1,30]]},"DOI":"10.1021\/acs.jafc.8b05770","type":"journal-article","created":{"date-parts":[[2018,12,28]],"date-time":"2018-12-28T10:56:17Z","timestamp":1545994577000},"page":"1104-1114","source":"Crossref","is-referenced-by-count":53,"title":["Hypocholesterolemic Effect of the Lignin-Rich Insoluble Residue of Brewer\u2019s Spent Grain in Mice Fed a High-Fat Diet"],"prefix":"10.1021","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4590-456X","authenticated-orcid":true,"given":"Ghulam Shere","family":"Raza","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Maukonen","sequence":"additional","affiliation":[{"name":"VTT Technical Research Centre of Finland, Limited, Post Office Box 1000, Tietotie 2, 02044 Espoo, Finland"},{"name":"DuPont Nutrition & Health, 02460 Kantvik, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Makinen","sequence":"additional","affiliation":[{"name":"Medical Research Center (MRC), University of Oulu and Oulu University Hospital, 90014 Oulu, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piritta","family":"Niemi","sequence":"additional","affiliation":[{"name":"VTT Technical Research Centre of Finland, Limited, Post Office Box 1000, Tietotie 2, 02044 Espoo, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Niiranen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley A.","family":"Hibberd","sequence":"additional","affiliation":[{"name":"Genomics & Microbiome Science, DuPont Nutrition & Health, St. Louis, Missouri 63110, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaisa","family":"Poutanen","sequence":"additional","affiliation":[{"name":"VTT Technical Research Centre of Finland, Limited, Post Office Box 1000, Tietotie 2, 02044 Espoo, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Buchert","sequence":"additional","affiliation":[{"name":"VTT Technical Research Centre of Finland, Limited, Post Office Box 1000, Tietotie 2, 02044 Espoo, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl-Heinz","family":"Herzig","sequence":"additional","affiliation":[{"name":"Medical Research Center (MRC), University of Oulu and Oulu University Hospital, 90014 Oulu, Finland"},{"name":"Department of Gastroenterology and Metabolism, Poznan University of Medical Sciences, 60-512 Poznan, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2018,12,28]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.suc.2005.04.006"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph6102568"},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1016\/S0140-6736(07)61778-4","volume":"370","author":"Prospective Studies Collaboration","year":"2007","journal-title":"Lancet"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114513001025"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.2009.00189.x"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.6486"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.seppur.2013.02.015"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/jf4024195"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/134.1.120"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.6b05552"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1159\/000214834"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-010-0645-9"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.etap.2012.04.005"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.3390\/molecules15129308"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.biortech.2013.03.076"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1002\/oby.21197"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6941.2006.00179.x"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.3945\/jn.112.166322"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3800680"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-8524(03)00073-7"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2008.12.012"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.3945\/jn.110.129056"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/132.6.1173"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/jf401738x"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1038\/197909a0"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1079\/BJN19830088"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.7762\/cnr.2018.7.1.31"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2014.10.004"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201500686"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-012-0479-1"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/80.5.1185"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/jf502062b"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.72.3.1729-1738.2006"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.305789"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.20.4.545"},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/0016-5085(80)90438-2","volume":"79","author":"Schwartz S. E.","year":"1980","journal-title":"Gastroenterology"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.29.04.06.dc05-2374"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M016246"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-003-0438-y"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0151829"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23721"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2010.215665"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1038\/nature12820"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1038\/nature16504"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1111\/1462-2920.13006"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1080\/21623945.2015.1061723"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2012-303304"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1038\/nature05414"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1038\/4441022a"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.nutres.2014.08.004"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114510001571"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.8466"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2007.08.009"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.6972"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2012.03.011"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1021\/jf204465j"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000235697.35431.05"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01075.2008"}],"container-title":["Journal of Agricultural and Food Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jafc.8b05770","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T18:49:00Z","timestamp":1681584540000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jafc.8b05770"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,28]]},"references-count":58,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,1,30]]}},"alternative-id":["10.1021\/acs.jafc.8b05770"],"URL":"https:\/\/doi.org\/10.1021\/acs.jafc.8b05770","relation":{},"ISSN":["0021-8561","1520-5118"],"issn-type":[{"value":"0021-8561","type":"print"},{"value":"1520-5118","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,28]]}}}