{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T14:47:39Z","timestamp":1760453259833,"version":"3.40.5"},"reference-count":65,"publisher":"American Chemical Society (ACS)","issue":"8","license":[{"start":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T00:00:00Z","timestamp":1711065600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T00:00:00Z","timestamp":1711065600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T00:00:00Z","timestamp":1711065600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Chem. Inf. Model."],"published-print":{"date-parts":[[2024,4,22]]},"DOI":"10.1021\/acs.jcim.3c01730","type":"journal-article","created":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T11:15:48Z","timestamp":1711106148000},"page":"3503-3523","source":"Crossref","is-referenced-by-count":3,"title":["Molecular Insights into the Variability in Infection and Immune Evasion Capabilities of SARS-CoV-2 Variants: A Sequence and Structural Investigation of the RBD Domain"],"prefix":"10.1021","volume":"64","author":[{"given":"Tian Hua","family":"Wang","sequence":"first","affiliation":[{"name":"College of Chemistry & Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hai Ping","family":"Shao","sequence":"additional","affiliation":[{"name":"College of Chemistry & Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7182-4993","authenticated-orcid":true,"given":"Bing Qiang","family":"Zhao","sequence":"additional","affiliation":[{"name":"College of Chemistry & Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7088-4962","authenticated-orcid":true,"given":"Hong Lin","family":"Zhai","sequence":"additional","affiliation":[{"name":"College of Chemistry & Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2024,3,22]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)01003-6"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2020.04.009"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1126\/science.1116480"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bty407"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.p1900"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.46234\/ccdcw2021.255"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2017.22.13.30494"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msab120"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.molbev.a040572"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1080\/10635150490522584"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btaa145"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.16498"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac1077"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky427"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.03.045"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2022.01.001"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abf1906"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2381-y"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-03807-6"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/pro.5560020916"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gki464"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/ct700301q"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jctc.5b00255"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/ct400751u"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1063\/1.445869"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1063\/1.1808117"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/jp8001614"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jctc.1c00645"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2180-5"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2179-y"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1126\/science.abb2762"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwaa101"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1126\/science.abb9983"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/0141-8130(83)90042-9"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-94602-w"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-33088-0"},{"key":"ref37\/cit37","unstructured":"R., W. Glycoprotein Builder www.glycam.org."},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20820"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-5-367"},{"key":"ref40\/cit40","unstructured":"An EUA for Bamlanivimab\nand Etesevimab for COVID-19.  Med. Lett. Drugs\nTher. 2021, 63, 49\u201350."},{"key":"ref41\/cit41","unstructured":"An EUA for Sotrovimab\nfor Treatment of COVID-19.  Med. Lett. Drugs\nTher. 2021, 63, 97\u201398."},{"key":"ref42\/cit42","unstructured":"COVID-19 updates:\nFDA restricts use of sotrovimab.  The Medical\nletter on drugs and therapeutics 2022, 64, 64."},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-81-1-181"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.62.11.4288-4295.1988"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01925-19"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2008.01.025"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M509233200"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.22.13848-13855.2005"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1186\/s12985-019-1182-0"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23062986"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsb.2010.11.021"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1010627"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2021.11.005"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1063\/1.4978893"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcb.2c07079"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c04798"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jctc.1c00374"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2019.00094"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2100425118"},{"key":"ref60\/cit60","doi-asserted-by":"crossref","first-page":"2254","DOI":"10.1038\/s41467-024-46490-7","volume":"15","author":"Planas D.","year":"2024","journal-title":"Nat. Commun."},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1016\/s1473-3099(23)00575-3"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7600640"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1126\/science.abc0870"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-05644-7"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.830527"}],"container-title":["Journal of Chemical Information and Modeling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jcim.3c01730","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jcim.3c01730","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T08:12:23Z","timestamp":1713773543000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jcim.3c01730"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,22]]},"references-count":65,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,4,22]]}},"alternative-id":["10.1021\/acs.jcim.3c01730"],"URL":"https:\/\/doi.org\/10.1021\/acs.jcim.3c01730","relation":{},"ISSN":["1549-9596","1549-960X"],"issn-type":[{"type":"print","value":"1549-9596"},{"type":"electronic","value":"1549-960X"}],"subject":[],"published":{"date-parts":[[2024,3,22]]}}}