{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T09:00:25Z","timestamp":1780909225485,"version":"3.54.1"},"reference-count":34,"publisher":"American Chemical Society (ACS)","issue":"11","license":[{"start":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T00:00:00Z","timestamp":1779062400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T00:00:00Z","timestamp":1779062400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T00:00:00Z","timestamp":1779062400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62372205"],"award-info":[{"award-number":["62372205"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62472192"],"award-info":[{"award-number":["62472192"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Chem. Inf. Model."],"published-print":{"date-parts":[[2026,6,8]]},"DOI":"10.1021\/acs.jcim.6c00042","type":"journal-article","created":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T17:06:34Z","timestamp":1779123994000},"page":"6768-6781","source":"Crossref","is-referenced-by-count":0,"title":["Conditional Diffusion Model-Based Method for Annotation of Antibiotic Resistance Gene Properties"],"prefix":"10.1021","volume":"66","author":[{"given":"Wen","family":"Kong","sequence":"first","affiliation":[{"name":"Hubei Provincial Key Laboratory of Artificial Intelligence and Smart Learning","place":["Wuhan, P. R. China"]},{"name":"Central China Normal University","place":["Wuhan, P. R. China"]},{"name":"School of Computer","place":["Wuhan, P. R. China"]},{"name":"Central China Normal University","place":["Wuhan, P. R. China"]},{"name":"National Language Resources Monitoring & Research Center for Network Media","place":["Wuhan, P. R. China"]},{"name":"Central China Normal University","place":["Wuhan, P. R. China"]},{"name":"Center for Intelligent Drug Discovery, Academy of Frontier Interdisciplinary Research","place":["Wuhan, P. R. China"]},{"name":"Central China Normal University","place":["Wuhan, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junze","family":"Wu","sequence":"additional","affiliation":[{"name":"Hubei Provincial Key Laboratory of Artificial Intelligence and Smart Learning","place":["Wuhan, P. R. China"]},{"name":"Central China Normal University","place":["Wuhan, P. R. China"]},{"name":"School of Computer","place":["Wuhan, P. R. China"]},{"name":"Central China Normal University","place":["Wuhan, P. R. China"]},{"name":"National Language Resources Monitoring & Research Center for Network Media","place":["Wuhan, P. R. China"]},{"name":"Central China Normal University","place":["Wuhan, P. R. China"]},{"name":"Center for Intelligent Drug Discovery, Academy of Frontier Interdisciplinary Research","place":["Wuhan, P. R. China"]},{"name":"Central China Normal University","place":["Wuhan, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8552-6084","authenticated-orcid":true,"given":"Weizhong","family":"Zhao","sequence":"additional","affiliation":[{"name":"Hubei Provincial Key Laboratory of Artificial Intelligence and Smart Learning","place":["Wuhan, P. R. China"]},{"name":"Central China Normal University","place":["Wuhan, P. R. China"]},{"name":"School of Computer","place":["Wuhan, P. R. China"]},{"name":"Central China Normal University","place":["Wuhan, P. R. China"]},{"name":"National Language Resources Monitoring & Research Center for Network Media","place":["Wuhan, P. R. China"]},{"name":"Central China Normal University","place":["Wuhan, P. R. China"]},{"name":"Center for Intelligent Drug Discovery, Academy of Frontier Interdisciplinary Research","place":["Wuhan, P. R. China"]},{"name":"Central China Normal University","place":["Wuhan, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,5,18]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1007\/s11756-021-00697-x"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-022-00820-y"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/s41576-019-0108-4"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbac052"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btae180"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btx680"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-018-0401-z"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-021-01002-3"},{"key":"ref9\/cit9","unstructured":"Ho, J.; Jain, A.; Abbeel, P.Denoising diffusion probabilistic models. In\n                      Advances in Neural Information Processing Systems\n                      ; Curran Associates, Inc., 2020; Vol. 33, pp 6840\u20136851."},{"key":"ref10\/cit10","unstructured":"Sohl-Dickstein, J.; Weiss, E.; Maheswaranathan, N.; Ganguli, S.Deep unsupervised learning using nonequilibrium thermodynamics. In\n                      International conference on machine learning\n                      ; PMLR, 2015; pp 2256\u20132265."},{"key":"ref11\/cit11","unstructured":"Nichol, A. Q.; Dhariwal, P.Improved denoising diffusion probabilistic models. In\n                      International conference on machine learning\n                      ; PMLR, 2021; pp 8162\u20138171."},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1109\/TPAMI.2023.3261988"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","unstructured":"Huang, R.; Lam, M. W.; Wang, J.; Su, D.; Yu, D.; Ren, Y.; Zhao, Z. Fastdiff: A fast conditional diffusion model for high-quality speech synthesis. arXiv preprint arXiv:2204.09934 2022.","DOI":"10.24963\/ijcai.2022\/577"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1145\/3422622"},{"key":"ref15\/cit15","unstructured":"Pu, Y.; Gan, Z.; Henao, R.; Yuan, X.; Li, C.; Stevens, A.; Carin, L. Variational autoencoder for deep learning of images, labels and captions. In\n                      Advances in Neural Information Processing Systems\n                      ; Curran Associates, Inc., Vol. 29, 2016."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","unstructured":"Zhang, L.; Rao, A.; Agrawala, M.Adding conditional control to text-to-image diffusion models. In\n                      Proceedings of the IEEE\/CVF international conference on computer vision\n                      ; IEEE, 2023; pp 3836\u20133847.","DOI":"10.1109\/ICCV51070.2023.00355"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks261"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01310-13"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/ismej.2014.106"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw1009"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00483-19"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz935"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.59717\/j.xinn-life.2024.100054"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btad690"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btae550"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkl164"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3176"},{"key":"ref28\/cit28","first-page":"3","volume":"741","author":"Reynolds D. A.","year":"2009","journal-title":"Encyclopedia of Biometrics"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btac020"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2016239118"},{"key":"ref31\/cit31","doi-asserted-by":"crossref","unstructured":"Zhu, Y.; Li, Z.; Wang, T.; He, M.; Yao, C.Conditional Text Image Generation With Diffusion Models. In\n                      Proceedings of the IEEE\/CVF Conference on Computer Vision and Pattern Recognition (CVPR)\n                      ; IEEE, 2023; pp 14235\u201314245.","DOI":"10.1109\/CVPR52729.2023.01368"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.engappai.2024.109583"},{"key":"ref33\/cit33","doi-asserted-by":"crossref","unstructured":"Chen, C.F. R.; Fan, Q.; Panda, R.Crossvit: Cross-attention multi-scale vision transformer for image classification. In\n                      Proceedings of the IEEE\/CVF international conference on computer vision\n                      ; IEEE, 2021; pp 357\u2013366.","DOI":"10.1109\/ICCV48922.2021.00041"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1109\/TPAMI.2018.2858826"}],"container-title":["Journal of Chemical Information and Modeling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jcim.6c00042","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jcim.6c00042","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T08:11:29Z","timestamp":1780906289000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jcim.6c00042"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,18]]},"references-count":34,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,6,8]]}},"alternative-id":["10.1021\/acs.jcim.6c00042"],"URL":"https:\/\/doi.org\/10.1021\/acs.jcim.6c00042","relation":{},"ISSN":["1549-9596","1549-960X"],"issn-type":[{"value":"1549-9596","type":"print"},{"value":"1549-960X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,18]]}}}