{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T13:08:38Z","timestamp":1788872918485,"version":"build-2803163510"},"reference-count":58,"publisher":"American Chemical Society (ACS)","issue":"17","license":[{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T00:00:00Z","timestamp":1787270400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFA1503000"],"award-info":[{"award-number":["2022YFA1503000"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22388102"],"award-info":[{"award-number":["22388102"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22525302"],"award-info":[{"award-number":["22525302"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The predictive fidelity of machine learning force fields (MLFFs) is often limited by the epistemic uncertainty and architectural biases of individual models. Here, we introduce ensemble learning of machine learning force fields (EL-MLFFs), a model-agnostic framework that utilizes a graph neural network (GNN) to integrate predictions from diverse base MLFFs and exploit their complementary error patterns. We propose two fusion architectures: a computationally efficient direct fusion model and a conservative fusion model enforcing energy\u2013force consistency by construction. Evaluated across chemically distinct settings\u2500including methanol adsorption on Cu(100), an in-house elastin-like peptide benchmark, and additional molecular and materials benchmarks\u2500the framework outperforms the evaluated single-model baselines in force MAEs. Across the tested systems, EL-MLFFs also improves several practical simulation-reliability metrics. However, fusing multiple base models can amplify numerical errors and energy drift in finite-precision simulations, even when energy\u2013force consistency is enforced analytically, highlighting numerical stability as a remaining challenge.<\/jats:p>","DOI":"10.1021\/acs.jctc.6c00021","type":"journal-article","created":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T05:05:50Z","timestamp":1787375150000},"page":"9066-9075","source":"Crossref","is-referenced-by-count":0,"title":["Ensemble Learning\nof Machine Learning Force Fields"],"prefix":"10.1021","volume":"22","author":[{"given":"Bangchen","family":"Yin","sequence":"first","affiliation":[{"name":"Tsinghua University , , ,","place":["Beijing, China, 100084"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Yin","sequence":"additional","affiliation":[{"name":"Tsinghua University , , ,","place":["Beijing, China, 100084"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuda W.","family":"Tang","sequence":"additional","affiliation":[{"name":"Tsinghua University , , ,","place":["Beijing, China, 100084"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9399-1584","authenticated-orcid":true,"given":"Hai","family":"Xiao","sequence":"additional","affiliation":[{"name":"Tsinghua University , , ,","place":["Beijing, China, 100084"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,8,21]]},"reference":[{"key":"2026090808093475900_cit1","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1038\/267585a0","article-title":"Dynamics of folded proteins","volume":"267","author":"McCammon","year":"1977","journal-title":"Nature"},{"key":"2026090808093475900_cit2","first-page":"449","article-title":"others\nMultiscale simulation and cinematic visualization of SARS-CoV-2 entry\nand egress","volume":"35","author":"Amaro","year":"2021","journal-title":"Int. J. High Perform. Comput. Appl."},{"key":"2026090808093475900_cit3","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1038\/nchem.1192","article-title":"Large-scale\nscreening of hypothetical\nmetal\u2013organic frameworks","volume":"4","author":"Wilmer","year":"2012","journal-title":"Nat. Chem."},{"key":"2026090808093475900_cit4","doi-asserted-by":"publisher","first-page":"5179","DOI":"10.1021\/ja00124a002","article-title":"A Second Generation Force Field for the Simulation\nof Proteins, Nucleic Acids, and Organic Molecules","volume":"117","author":"Cornell","year":"1995","journal-title":"J. Am. Chem. Soc."},{"key":"2026090808093475900_cit5","doi-asserted-by":"publisher","first-page":"3586","DOI":"10.1021\/jp973084f","article-title":"others All-Atom Empirical\nPotential for Molecular Modeling and Dynamics Studies of Proteins","volume":"102","author":"MacKerell","year":"1998","journal-title":"J. Phys. Chem. B"},{"key":"2026090808093475900_cit6","doi-asserted-by":"publisher","first-page":"9396","DOI":"10.1021\/jp004368u","article-title":"ReaxFF:\nA Reactive Force Field for Hydrocarbons","volume":"105","author":"van Duin","year":"2001","journal-title":"J.\nPhys. Chem. A"},{"key":"2026090808093475900_cit7","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1103\/RevModPhys.79.291","article-title":"Coupled-cluster\ntheory in quantum chemistry","volume":"79","author":"Bartlett","year":"2007","journal-title":"Rev. Mod. Phys."},{"key":"2026090808093475900_cit8","doi-asserted-by":"publisher","first-page":"146401","DOI":"10.1103\/PhysRevLett.98.146401","article-title":"Generalized\nNeural-Network Representation of High-Dimensional\nPotential-Energy Surfaces","volume":"98","author":"Behler","year":"2007","journal-title":"Phys. Rev. Lett."},{"key":"2026090808093475900_cit9","first-page":"2002424","article-title":"Machine Learning\nInteratomic Potentials\nas an Emerging Tool for Materials Science","volume":"33","author":"Deringer","year":"2021","journal-title":"Adv.\nMater."},{"key":"2026090808093475900_cit10","doi-asserted-by":"publisher","first-page":"136403","DOI":"10.1103\/PhysRevLett.104.136403","article-title":"Gaussian Approximation\nPotentials: The Accuracy of Quantum Mechanics, without the Electrons","volume":"104","author":"Barto\u0301k","year":"2010","journal-title":"Phys. Rev. Lett."},{"key":"2026090808093475900_cit11","doi-asserted-by":"publisher","first-page":"241722","DOI":"10.1063\/1.5019779","article-title":"SchNet \u2013 A deep learning architecture\nfor molecules\nand materials","volume":"148","author":"Schu\u0308tt","year":"2018","journal-title":"J. Chem. Phys."},{"key":"2026090808093475900_cit12","doi-asserted-by":"publisher","first-page":"2453","DOI":"10.1038\/s41467-022-29939-5","article-title":"E(3)-equivariant\ngraph neural networks for data-efficient and accurate interatomic\npotentials","volume":"13","author":"Batzner","year":"2022","journal-title":"Nat. Commun."},{"key":"2026090808093475900_cit13","doi-asserted-by":"publisher","first-page":"184110","DOI":"10.1063\/5.0297006","article-title":"A foundation model for atomistic materials\nchemistry","volume":"163","author":"Batatia","year":"2025","journal-title":"J. Chem. Phys."},{"key":"2026090808093475900_cit14","doi-asserted-by":"publisher","first-page":"arXiv:2501.07155","DOI":"10.48550\/arXiv.2501.07155","article-title":"AlphaNet:\nScaling Up Local-frame-based Atomistic Interatomic Potential","author":"Yin","year":"2025","journal-title":"arXiv"},{"key":"2026090808093475900_cit15","doi-asserted-by":"publisher","first-page":"4857","DOI":"10.1021\/acs.jctc.4c00190","article-title":"Scalable parallel algorithm for graph\nneural network interatomic potentials in molecular dynamics simulations","volume":"20","author":"Park","year":"2024","journal-title":"J. Chem. Theory Comput."},{"key":"2026090808093475900_cit16","doi-asserted-by":"publisher","first-page":"arXiv:2405.04967","DOI":"10.48550\/arXiv.2405.04967","article-title":"others Mattersim: A\ndeep learning atomistic model across elements, temperatures and pressures","author":"Yang","year":"2024","journal-title":"arXiv"},{"key":"2026090808093475900_cit17","doi-asserted-by":"publisher","first-page":"arXiv:2502.12147","DOI":"10.48550\/arXiv.2502.12147","article-title":"Learning\nsmooth and expressive interatomic\npotentials for physical property prediction","author":"Fu","year":"2025","journal-title":"arXiv"},{"key":"2026090808093475900_cit18","doi-asserted-by":"crossref","first-page":"11423","DOI":"10.52202\/068431-0830","article-title":"MACE: Higher\norder equivariant message passing neural networks for fast and accurate\nforce fields","volume":"35","author":"Batatia","year":"2022","journal-title":"Adv. Neural Inf. Process. Syst."},{"key":"2026090808093475900_cit19","doi-asserted-by":"publisher","first-page":"arXiv:2506.01686","DOI":"10.48550\/arXiv.2506.01686","article-title":"others A graph neural network for the era of large\natomistic models","author":"Wang","year":"2025","journal-title":"arXiv"},{"key":"2026090808093475900_cit20","doi-asserted-by":"publisher","first-page":"arXiv:2508.17936","DOI":"10.48550\/arXiv.2508.17936","article-title":"Graph atomic cluster expansion for\nfoundational machine learning interatomic potentials","author":"Lysogorskiy","year":"2025","journal-title":"arXiv"},{"key":"2026090808093475900_cit21","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.1603015","article-title":"Machine learning of accurate energy-conserving\nmolecular force fields","volume":"3","author":"Chmiela","year":"2017","journal-title":"Sci. Adv."},{"key":"2026090808093475900_cit22","doi-asserted-by":"publisher","first-page":"015311","DOI":"10.1103\/PhysRevE.105.015311","article-title":"Quality of uncertainty estimates from neural network\npotential ensembles","volume":"105","author":"Kahle","year":"2022","journal-title":"Phys. Rev. E"},{"key":"2026090808093475900_cit23","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1038\/s41524-023-01180-8","article-title":"Single-model uncertainty quantification\nin neural network potentials does not consistently outperform model\nensembles","volume":"9","author":"Tan","year":"2023","journal-title":"npj Comput. Mater."},{"key":"2026090808093475900_cit24","doi-asserted-by":"publisher","first-page":"104105","DOI":"10.1063\/5.0016004","article-title":"Committee neural network\npotentials\ncontrol generalization errors and enable active learning","volume":"153","author":"Schran","year":"2020","journal-title":"J. Chem. Phys."},{"key":"2026090808093475900_cit25","doi-asserted-by":"publisher","first-page":"064114","DOI":"10.1103\/PhysRevB.99.064114","article-title":"Accelerating crystal\nstructure prediction by machine-learning interatomic potentials with\nactive learning","volume":"99","author":"Podryabinkin","year":"2019","journal-title":"Phys. Rev. B"},{"key":"2026090808093475900_cit26","doi-asserted-by":"publisher","first-page":"107206","DOI":"10.1016\/j.cpc.2020.107206","article-title":"DP-GEN: A concurrent learning platform\nfor the generation of reliable deep learning based potential energy\nmodels","volume":"253","author":"Zhang","year":"2020","journal-title":"Comput. Phys. Commun."},{"key":"2026090808093475900_cit27","article-title":"An ensemble method\nfor training high-precision neural\nnetwork interatomic potentials","volume":"1","author":"Wang","year":"2020","journal-title":"AI Sci.: Mind\nMatter."},{"key":"2026090808093475900_cit28","doi-asserted-by":"publisher","first-page":"194106","DOI":"10.1063\/5.0007276","article-title":"Ensemble learning of coarse-grained\nmolecular dynamics\nforce fields with a kernel approach","volume":"152","author":"Wang","year":"2020","journal-title":"J. Chem.\nPhys."},{"key":"2026090808093475900_cit29","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1007\/bf00058655","article-title":"Bagging Predictors","volume":"24","author":"Breiman","year":"1996","journal-title":"Mach. Learn."},{"key":"2026090808093475900_cit30","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1007\/3-540-59119-2_166","article-title":"A Decision-Theoretic\nGeneralization of On-Line Learning\nand an Application to Boosting","volume":"904","author":"Freund","year":"1995","journal-title":"Comput. Learn.\nTheory"},{"key":"2026090808093475900_cit31","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/S0893-6080(05)80023-1","article-title":"Stacked\ngeneralization","volume":"5","author":"Wolpert","year":"1992","journal-title":"Neural Networks"},{"key":"2026090808093475900_cit32","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1162\/neco.1991.3.1.79","article-title":"Adaptive\nMixtures\nof Local Experts","volume":"3","author":"Jacobs","year":"1991","journal-title":"Neural Comput."},{"key":"2026090808093475900_cit33","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1162\/neco.1994.6.2.181","article-title":"Hierarchical Mixtures of Experts\nand the EM Algorithm","volume":"6","author":"Jordan","year":"1994","journal-title":"Neural Comput."},{"key":"2026090808093475900_cit34","first-page":"1","article-title":"Switch Transformers:\nScaling to Trillion\nParameter Models with Simple and Efficient Sparsity","volume":"23","author":"Fedus","year":"2022","journal-title":"J. Mach. Learn. Res."},{"key":"2026090808093475900_cit35","doi-asserted-by":"publisher","first-page":"114801","DOI":"10.1063\/5.0106617","article-title":"GPUMD: A package for constructing accurate machine-learned\npotentials and performing highly efficient atomistic simulations","volume":"157","author":"Fan","year":"2022","journal-title":"J. Chem. Phys."},{"key":"2026090808093475900_cit36","doi-asserted-by":"publisher","first-page":"143001","DOI":"10.1103\/PhysRevLett.120.143001","article-title":"Deep Potential Molecular Dynamics:\nA Scalable Model with the Accuracy of Quantum Mechanics","volume":"120","author":"Zhang","year":"2018","journal-title":"Phys. Rev. Lett."},{"key":"2026090808093475900_cit37","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.1137\/15M1054183","article-title":"Moment\ntensor potentials: a class of systematically improvable interatomic\npotentials","volume":"14","author":"Shapeev","year":"2016","journal-title":"Multiscale Model. Simul."},{"key":"2026090808093475900_cit38","doi-asserted-by":"publisher","first-page":"184115","DOI":"10.1103\/PhysRevB.87.184115","article-title":"On representing chemical environments","volume":"87","author":"Barto\u0301k","year":"2013","journal-title":"Phys. Rev. B:Condens. Matter Mater. Phys."},{"key":"2026090808093475900_cit39","doi-asserted-by":"publisher","first-page":"arXiv:1706.08566","DOI":"10.48550\/arXiv.1706.08566","article-title":"SchNet: A continuous-filter Convolutional Neural Network\nfor Modeling Quantum Interactions","author":"Schu\u0308tt","year":"2017","journal-title":"arXiv"},{"key":"2026090808093475900_cit40","unstructured":"Schu\u0308tt, K.; Unke, O.; Gastegger, M.\n          Equivariant message\npassing for the prediction of tensorial properties and molecular spectra. In  Proceedings of the 38th International Conference on\nMachine Learning; ICML, 2021; pp 9377\u20139388."},{"key":"2026090808093475900_cit41","doi-asserted-by":"publisher","first-page":"3185","DOI":"10.1021\/acs.jctc.7b00174","article-title":"Psi4 1.1: An Open-Source\nElectronic Structure Program Emphasizing Automation, Advanced Libraries,\nand Interoperability","volume":"13","author":"Parrish","year":"2017","journal-title":"J. Chem. Theory Comput."},{"key":"2026090808093475900_cit42","doi-asserted-by":"publisher","first-page":"6059","DOI":"10.1021\/acscatal.0c04525","article-title":"Open Catalyst 2020 (OC20) Dataset and Community\nChallenges","volume":"11","author":"Chanussot","year":"2021","journal-title":"ACS Catal."},{"key":"2026090808093475900_cit43","doi-asserted-by":"publisher","first-page":"7010","DOI":"10.1063\/1.480097","article-title":"A dimer method for finding saddle\npoints on high dimensional\npotential surfaces using only first derivatives","volume":"111","author":"Henkelman","year":"1999","journal-title":"J. Chem. Phys."},{"key":"2026090808093475900_cit44","doi-asserted-by":"publisher","first-page":"arXiv:2103.01436","DOI":"10.48550\/arXiv.2103.01436","article-title":"ForceNet: A Graph\nNeural Network for Large-Scale Quantum Calculations","author":"Hu","year":"2021","journal-title":"arXiv"},{"key":"2026090808093475900_cit45","unstructured":"Gasteiger, J.; Gro\u00df, J.; Gu\u0308nnemann, S.\n          Directional Message Passing\nfor Molecular Graphs; International Conference\non Learning Representations (ICLR), 2020."},{"key":"2026090808093475900_cit46","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1038\/s42256-023-00716-3","article-title":"CHGNet as\na pretrained universal\nneural network potential for charge-informed atomistic modelling","volume":"5","author":"Deng","year":"2023","journal-title":"Nat. Mach. Intell."},{"key":"2026090808093475900_cit47","doi-asserted-by":"publisher","first-page":"37334","DOI":"10.52202\/075280-1623","article-title":"Tensornet: Cartesian tensor representations for efficient\nlearning of molecular potentials","volume":"36","author":"Simeon","year":"2023","journal-title":"Adv. Neural\nInf. Process. Syst."},{"key":"2026090808093475900_cit48","doi-asserted-by":"publisher","first-page":"718","DOI":"10.1038\/s43588-022-00349-3","article-title":"A universal graph\ndeep learning interatomic potential\nfor the periodic table","volume":"2","author":"Chen","year":"2022","journal-title":"Nat. Comput. Sci."},{"key":"2026090808093475900_cit49","doi-asserted-by":"publisher","first-page":"arXiv:1710.10903","DOI":"10.48550\/arXiv.1710.10903","article-title":"Graph Attention Networks","author":"Velic\u030ckovic\u0301","year":"2018","journal-title":"arXiv"},{"key":"2026090808093475900_cit50","doi-asserted-by":"crossref","unstructured":"He, K.; Zhang, X.; Ren, S.; Sun, J.\n          Deep Residual Learning for Image Recognition. In  2016 IEEE Conference on Computer Vision and Pattern\nRecognition (CVPR); IEEE, 2016; pp 770\u2013778.","DOI":"10.1109\/CVPR.2016.90"},{"key":"2026090808093475900_cit51","doi-asserted-by":"publisher","first-page":"arXiv:1806.03536","DOI":"10.48550\/arXiv.1806.03536","article-title":"Representation Learning\non Graphs with Jumping Knowledge\nNetworks","author":"Xu","year":"2018","journal-title":"arXiv"},{"key":"2026090808093475900_cit52","doi-asserted-by":"publisher","first-page":"arXiv:2207.09453","DOI":"10.48550\/arXiv.2207.09453","article-title":"e3nn: Euclidean Neural\nNetworks","author":"Geiger","year":"2022","journal-title":"arXiv"},{"key":"2026090808093475900_cit53","doi-asserted-by":"publisher","first-page":"arXiv:2210.07237","DOI":"10.48550\/arXiv.2210.07237","article-title":"Forces are not Enough:\nBenchmark and Critical Evaluation\nfor Machine Learning Force Fields with Molecular Simulations","author":"Fu","year":"2023","journal-title":"arXiv"},{"key":"2026090808093475900_cit54","doi-asserted-by":"publisher","first-page":"arXiv:2503.04070","DOI":"10.48550\/arXiv.2503.04070","article-title":"A foundational potential\nenergy surface dataset for materials","author":"Kaplan","year":"2025","journal-title":"arXiv"},{"key":"2026090808093475900_cit55","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1038\/s41524-020-00481-6","article-title":"Predicting stable\ncrystalline compounds\nusing chemical similarity","volume":"7","author":"Wang","year":"2021","journal-title":"npj Comput. Mater."},{"key":"2026090808093475900_cit56","unstructured":"Zhang, L.; Han, J.; Wang, H.; Saidi, W. A.; Car, R.; Weinan, E.\n          End-To-End Symmetry Preserving Inter-atomic\nPotential Energy\nModel for Finite and Extended Systems; Proceedings\nof the 32nd International Conference on Neural Information Processing\nSystems: Red Hook, NY, USA, 2018; pp 4441\u20134451."},{"key":"2026090808093475900_cit57","doi-asserted-by":"publisher","first-page":"2130","DOI":"10.1103\/PhysRevA.7.2130","article-title":"Structure Factor\nand Radial Distribution Function for Liquid Argon at 85 \u00b0K","volume":"7","author":"Yarnell","year":"1973","journal-title":"Phys. Rev. A:At., Mol., Opt. Phys."},{"key":"2026090808093475900_cit58","doi-asserted-by":"publisher","first-page":"8415","DOI":"10.1088\/0953-8984\/6\/41\/006","article-title":"The radial\ndistribution function probed by X-ray absorption spectroscopy","volume":"6","author":"Filipponi","year":"1994","journal-title":"J. Phys.: Condens. Matter"}],"container-title":["Journal of Chemical Theory\nand Computation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jctc.6c00021","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/jctcce\/article-pdf\/22\/17\/9066\/66963030\/acs.jctc.6c00021.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/jctcce\/article-pdf\/22\/17\/9066\/66963030\/acs.jctc.6c00021.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:30:53Z","timestamp":1788870653000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/jctcce\/article\/22\/17\/9066\/5284176\/Ensemble-Learning-of-Machine-Learning-Force-Fields"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,21]]},"references-count":58,"journal-issue":{"issue":"17","published-online":{"date-parts":[[2026,8,21]]},"published-print":{"date-parts":[[2026,9,8]]}},"URL":"https:\/\/doi.org\/10.1021\/acs.jctc.6c00021","relation":{},"ISSN":["1549-9618","1549-9626"],"issn-type":[{"value":"1549-9618","type":"print"},{"value":"1549-9626","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,21]]}}}