{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T19:11:39Z","timestamp":1793041899809,"version":"4.5.0"},"reference-count":72,"publisher":"American Chemical Society (ACS)","issue":"3","license":[{"start":{"date-parts":[[2021,3,12]],"date-time":"2021-03-12T00:00:00Z","timestamp":1615507200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,3,12]],"date-time":"2021-03-12T00:00:00Z","timestamp":1615507200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,3,12]],"date-time":"2021-03-12T00:00:00Z","timestamp":1615507200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Nat. Prod."],"published-print":{"date-parts":[[2021,3,26]]},"DOI":"10.1021\/acs.jnatprod.0c01196","type":"journal-article","created":{"date-parts":[[2021,3,12]],"date-time":"2021-03-12T14:13:32Z","timestamp":1615558412000},"page":"846-856","source":"Crossref","is-referenced-by-count":11,"title":["The Untargeted Capability of NMR Helps Recognizing Nefarious Adulteration in Natural Products"],"prefix":"10.1021","volume":"84","author":[{"given":"Seon Beom","family":"Kim","sequence":"first","affiliation":[{"name":"Center for Natural Products Technologies (CENAPT), Program for Collaborative Research in the Pharmaceutical Sciences, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1640-9989","authenticated-orcid":true,"given":"Jonathan","family":"Bisson","sequence":"additional","affiliation":[{"name":"Center for Natural Products Technologies (CENAPT), Program for Collaborative Research in the Pharmaceutical Sciences, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0739-9224","authenticated-orcid":true,"given":"J. Brent","family":"Friesen","sequence":"additional","affiliation":[{"name":"Center for Natural Products Technologies (CENAPT), Program for Collaborative Research in the Pharmaceutical Sciences, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States"},{"name":"Physical Sciences Department, Rosary College of Arts and Sciences, Dominican University, River Forest, Illinois 60305, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Bucchini","sequence":"additional","affiliation":[{"name":"Hylobates, Consulting S.R.L., 00135 Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5709-5683","authenticated-orcid":true,"given":"Stefan","family":"Gafner","sequence":"additional","affiliation":[{"name":"American Botanical Council, Austin, Texas 78723, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3166-5980","authenticated-orcid":true,"given":"David C.","family":"Lankin","sequence":"additional","affiliation":[{"name":"Center for Natural Products Technologies (CENAPT), Program for Collaborative Research in the Pharmaceutical Sciences, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0748-0863","authenticated-orcid":true,"given":"Shao-Nong","family":"Chen","sequence":"additional","affiliation":[{"name":"Center for Natural Products Technologies (CENAPT), Program for Collaborative Research in the Pharmaceutical Sciences, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1022-4326","authenticated-orcid":true,"given":"Guido F.","family":"Pauli","sequence":"additional","affiliation":[{"name":"Center for Natural Products Technologies (CENAPT), Program for Collaborative Research in the Pharmaceutical Sciences, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1696-8828","authenticated-orcid":true,"given":"James B.","family":"McAlpine","sequence":"additional","affiliation":[{"name":"Center for Natural Products Technologies (CENAPT), Program for Collaborative Research in the Pharmaceutical Sciences, Pharmacognosy Institute, and Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2021,3,12]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.5b01009"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.6b00975"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.9b00020"},{"key":"ref4\/cit4","unstructured":"Antony, B. Treatment of Alzheimer\u2019s with a curcuminoid mixture and essential oil of turmeric having 45% Ar-turmerone U.S. Patent 8,859,020 B2, 2014."},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1021\/np300066q"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/0300-483X(80)90122-5"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-960004"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-957450"},{"key":"ref9\/cit9","unstructured":"Watson, E. EuroPharma to launch probe into synthetic vs natural curcumin. https:\/\/www.nutraingredients-usa.com\/Article\/2011\/09\/07\/EuroPharma-to-launch-probe-into-synthetic-vs-natural-curcumin (accessed Sep 6, 2011)."},{"key":"ref10\/cit10","unstructured":"Daniells, S. Study highlights progress in turmeric supplement quality, but concerns around synthetic curcumin adulteration. https:\/\/www.nutraingredients-usa.com\/Article\/2018\/06\/18\/Study-highlights-progress-in-turmeric-supplement-quality-but-concerns-around-synthetic-curcumin-adulteration (accessed Jun 18, 2018)."},{"key":"ref11\/cit11","unstructured":"Sabinsa Corporation. Sabinsa takes action against Biotikon\nfor synthetic curcumin adulteration. https:\/\/www.sabinsa.com\/press-release-2017\/190-sabinsa-takes-action-against-biotikon-for-synthetic-curcumin-adulteration (accessed Apr 11, 2017)."},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1872-034X.2008.00486.x"},{"key":"ref13\/cit13","volume":"2018","author":"Lukefahr A. L.","year":"2018","journal-title":"BMJ. Case Rep."},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/6741213"},{"key":"ref15\/cit15","unstructured":"Committee\non Herbal Medicinal\nProducts (HMPC). Assessment\nreport on\n                      Curcuma longa\n                      L. rhizoma. https:\/\/www.ema.europa.eu\/en\/documents\/herbal-report\/final-assessment-report-curcuma-longa-l-rhizoma-revision-1_en.pdf (accessed Sep 24, 2018)."},{"key":"#cr-split#-ref16\/cit16.1","doi-asserted-by":"crossref","unstructured":"Bucchini, L. The 2019 Curcumin Crisis in Italy: What We Know so Far, and Early Lessons. 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Products Research (GA) in Cooperation with the French Society of Pharmacognosy AFERP","DOI":"10.1055\/s-0039-3399667"},{"key":"#cr-split#-ref16\/cit16.2","unstructured":"Innsbruck, Austria, Sep 1-5, 2019."},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1007\/s11739-019-02145-w"},{"key":"ref18\/cit18","unstructured":"Bejar, E. Adulteration of turmeric (\n                      Curcuma longa\n                      ) root and rhizome, and root and rhizome extracts. http:\/\/cms.herbalgram.org\/BAP\/BAB\/TurmericRootandRhizomeandExtracts.html (accessed May, 2018)."},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2019.108722"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.9b00744"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.hermed.2019.100281"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2013.12.042"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2008.08.014"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/jf025506a"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2013.12.039"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.3390\/molecules191220091"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.200900453"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.201500686"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/jsfa.8364"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2012.08.003"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.7324\/JAPS.2018.8610"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2014.10.011"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/np501065h"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/jf801815n"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2017.04.055"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1546246"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2019.05.057"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1021\/jm500734a"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8137.2005.01632.x"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.3945\/an.115.009928"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2017.11.017"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1021\/np0497301"},{"key":"ref43\/cit43","volume-title":"Biochemistry and Molecular Biology of Plants","author":"Buchanan B. B.","year":"2015"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1186\/1746-4811-6-14"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1038\/35081178"},{"key":"ref46\/cit46","first-page":"126","volume":"154","author":"Harborne J. B.","year":"1990","journal-title":"Ciba Found. Symp."},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2019.103728"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.21775\/cimb.023.001"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.12.4.564"},{"key":"ref50\/cit50","first-page":"255","volume":"171","author":"Waterman P. G.","year":"2007","journal-title":"Ciba Found. Symp."},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1177\/009286159903300308"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1039\/c1fo10112a"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1002\/cpt.1119"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-012-6595-1"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2016.02.026"},{"key":"ref56\/cit56","doi-asserted-by":"crossref","unstructured":"Integratori alimentari contenenti\nestratti e preparati di\n                      Curcuma longa.\n                      http:\/\/www.salute.gov.it\/portale\/news\/p3_2_1_1_1.jsp?lingua=italiano&menu=notizie&p=dalministero&id=3842 (accessed Jul 26, 2019).","DOI":"10.1155\/2019\/5160293"},{"key":"ref57\/cit57","unstructured":"The Federal Public Service\n(FPS) Health, Commission d\u2019avis des pr\u00e9parations de\nplantes.\n                      Avis Du 24 Octobre 2019 Rendu\nPar La Commission D\u2019avis Des Pr\u00e9parations de Plantes\nConcernant L\u2019utilisation de Compl\u00e9ments Alimentaires\nContenant Des Curcuminoides\n                      ; 2019."},{"key":"ref58\/cit58","first-page":"1679","volume":"8","author":"European Food Safety Authority, Scientific Opinion on the Re-evaluation of Curcumin (E 100) as a Food Additive.","year":"2010","journal-title":"EFSA J."},{"key":"ref59\/cit59","unstructured":"Food\nSafety Authority of Ireland.\n                      Natures\nAid Is Withdrawing All Batches of\nIts Turmeric due to High Levels of Curcumin\n                      , 2018."},{"key":"ref60\/cit60","volume-title":"Tetrahydrocurcuminoids from Turmeric","author":"Sabinsa Europe GmbH.","year":"2020"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1093\/jaoac\/91.6.1387"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.22159\/ijap.2018v10i6.29014"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.5740\/jaoacint.17-0111"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1002\/pca.1129"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.17660\/ActaHortic.2008.786.18"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1177\/0033354917700109"},{"key":"ref67\/cit67","unstructured":"Food Safety\nand Standards Authority\nof India (FSSAI). Manual of\nsimple methods for testing of common adulterants in food; New Delhi, India, 2017; pp 1\u201355."},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.2174\/2210290601102010028"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2010.07.025"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1021\/acs.oprd.6b00347"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201800143"}],"container-title":["Journal of Natural Products"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jnatprod.0c01196","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T18:52:47Z","timestamp":1682535167000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jnatprod.0c01196"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,12]]},"references-count":72,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3,26]]}},"alternative-id":["10.1021\/acs.jnatprod.0c01196"],"URL":"https:\/\/doi.org\/10.1021\/acs.jnatprod.0c01196","relation":{"has-preprint":[{"id-type":"doi","id":"10.26434\/chemrxiv.13173698.v1","asserted-by":"object"}]},"ISSN":["0163-3864","1520-6025"],"issn-type":[{"value":"0163-3864","type":"print"},{"value":"1520-6025","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,12]]}}}