{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T20:01:33Z","timestamp":1775678493734,"version":"3.50.1"},"reference-count":40,"publisher":"American Chemical Society (ACS)","issue":"8","license":[{"start":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T00:00:00Z","timestamp":1627948800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T00:00:00Z","timestamp":1627948800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T00:00:00Z","timestamp":1627948800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Nat. Prod."],"published-print":{"date-parts":[[2021,8,27]]},"DOI":"10.1021\/acs.jnatprod.1c00374","type":"journal-article","created":{"date-parts":[[2021,8,3]],"date-time":"2021-08-03T15:22:02Z","timestamp":1628004122000},"page":"2272-2281","source":"Crossref","is-referenced-by-count":10,"title":["Monomeric, Dimeric, and Trimeric Tropane Alkaloids from <i>Pellacalyx saccardianus<\/i>"],"prefix":"10.1021","volume":"84","author":[{"given":"Zi-Yang","family":"Chan","sequence":"first","affiliation":[{"name":"School of Pharmacy, University of Nottingham Malaysia, Jalan Broga, 43500 Semenyih, Selangor, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Premanand","family":"Krishnan","sequence":"additional","affiliation":[{"name":"School of Pharmacy, University of Nottingham Malaysia, Jalan Broga, 43500 Semenyih, Selangor, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sayed Mohammadhossein","family":"Modaresi","sequence":"additional","affiliation":[{"name":"School of Pharmacy, University of Nottingham Malaysia, Jalan Broga, 43500 Semenyih, Selangor, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling-Wei","family":"Hii","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun-Wai","family":"Mai","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oncogenes and Related Genes, Renji-Med X Clinical Stem Cell Research Center, Department of Urology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-Meng","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chee-Onn","family":"Leong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7429-4238","authenticated-orcid":true,"given":"Yun-Yee","family":"Low","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soon-Kit","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kien-Thai","family":"Yong","sequence":"additional","affiliation":[{"name":"Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alyssa Zi-Xin","family":"Leong","sequence":"additional","affiliation":[{"name":"School of Pharmacy, University of Nottingham Malaysia, Jalan Broga, 43500 Semenyih, Selangor, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei-Kee","family":"Lee","sequence":"additional","affiliation":[{"name":"School of Pharmacy, University of Nottingham Malaysia, Jalan Broga, 43500 Semenyih, Selangor, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kang-Nee","family":"Ting","sequence":"additional","affiliation":[{"name":"School of Pharmacy, University of Nottingham Malaysia, Jalan Broga, 43500 Semenyih, Selangor, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1462-3324","authenticated-orcid":true,"given":"Kuan-Hon","family":"Lim","sequence":"additional","affiliation":[{"name":"School of Pharmacy, University of Nottingham Malaysia, Jalan Broga, 43500 Semenyih, Selangor, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2021,8,3]]},"reference":[{"key":"ref1\/cit1","first-page":"439","volume":"60","author":"Grynkiewicz G.","year":"2008","journal-title":"Pharmacol. Rep."},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9422(99)00475-6"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1039\/D0NP00076K"},{"key":"ref4\/cit4","doi-asserted-by":"crossref","unstructured":"Afewerki, S.; Wang, J. X.; Liao, W. W.; C\u00f3rdova, A. In  The Alkaloids: Chemistry and Biology; Kn\u00f6lker, H. J., Ed. Elsevier: Cambridge, MA, 2019; Vol. 81, Chapter 3, pp 151\u2013233.","DOI":"10.1016\/bs.alkal.2018.06.001"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1071\/CH9911013"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1071\/CH9691271"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(00)70172-9"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/np50027a017"},{"key":"ref9\/cit9","unstructured":"Hou, D. In  Flora Malesiana, Series I, Spermatophyta, Rhizophoraceae; van Steenis, C. G. G. J., Ed. P. Noordhoff Ltd: Groningen, The Netherlands, 1957; Vol. 5, pp 429\u2013493."},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytol.2015.05.001"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.11113\/jt.v78.7806"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9422(86)80015-2"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1002\/jps.2600670611"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/np50045a023"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1565(199807\/08)9:4<168::AID-PCA408>3.0.CO;2-Q"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/np040144h"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1039\/j39660000074"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/mrc.3909"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/np50063a032"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/ja00739a022"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1023\/B:CONC.0000025466.77810.83"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2013.01.042"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.200800290"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1007\/s11101-018-9598-5"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/np200450y"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1007\/BF00575051"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2006.11.037"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2006.05.182"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-990876"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1007\/s10495-018-1459-6"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1038\/nature16965"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20184504"},{"key":"ref33\/cit33","first-page":"781","volume":"14","author":"Cherkez S.","year":"1978","journal-title":"Mol. Pharmacol."},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/jm00187a004"},{"key":"ref35\/cit35","unstructured":"Spartan\u201914; Wavefunction,\nInc.: Irvine, CA, 2014."},{"key":"ref36\/cit36","unstructured":"Frisch, M. J.; Trucks, G. W.; Schlegel, H. B.; Scuseria, G. E.; Robb, M. A.; Cheeseman, J. R.; Scalmani, G.; Barone, V.; Mennucci, B.; Petersson, G. A.; Nakatsuji, H.; Caricato, M.; Li, X.; Hratchian, H. P.; Izmaylov, A. F.; Bloino, J.; Zheng, G.; Sonnenberg, J. L.; Hada, M.; Ehara, M.; Toyota, K.; Fukuda, R.; Hasegawa, J.; Ishida, M.; Nakajima, T.; Honda, Y.; Kitao, O.; Nakai, H.; Vreven, T.; Montgomery, J. A., Jr.; Peralta, J. E.; Ogliaro, F.; Bearpark, M.; Heyd, J. J.; Brothers, E.; Kudin, K. N.; Staroverov, V. N.; Keith, T.; Kobayashi, R.; Normand, J.; Raghavachari, K.; Rendell, A.; Burant, J. C.; Iyengar, S. S.; Tomasi, J.; Cossi, M.; Rega, N.; Millam, J. M.; Klene, M.; Knox, J. E.; Cross, J. B.; Bakken, V.; Adamo, C.; Jaramillo, J.; Gomperts, R.; Stratmann, R. E.; Yazyev, O.; Austin, A. J.; Cammi, R.; Pomelli, C.; Ochterski, J. W.; Martin, R. L.; Morokuma, K.; Zakrzewski, V. G.; Voth, G. A.; Salvador, P.; Dannenberg, J. J.; Dapprich, S.; Daniels, A. D.; Farkas, \u00d6.; Foresman, J. B.; Ortiz, J. V.; Cioslowski, J.; Fox, D. J. Gaussian 09, Revision C.01; Gaussian Inc.: Wallingford, CT, 2010."},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.9b00725"},{"key":"ref38\/cit38","unstructured":"Bruhn, T.; Schauml\u00f6ffel, A.; Hemberger, Y.; Pescitelli, G. SpecDis version 1.71; Berlin, Germany, 2017; https:\/\/specdis-software.jimdo.com\/."},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1002\/chir.22138"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2018.03.025"}],"container-title":["Journal of Natural Products"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jnatprod.1c00374","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T20:14:42Z","timestamp":1682626482000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jnatprod.1c00374"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,3]]},"references-count":40,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8,27]]}},"alternative-id":["10.1021\/acs.jnatprod.1c00374"],"URL":"https:\/\/doi.org\/10.1021\/acs.jnatprod.1c00374","relation":{},"ISSN":["0163-3864","1520-6025"],"issn-type":[{"value":"0163-3864","type":"print"},{"value":"1520-6025","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,3]]}}}