{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T11:48:41Z","timestamp":1771328921077,"version":"3.50.1"},"reference-count":46,"publisher":"American Chemical Society (ACS)","issue":"4","license":[{"start":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T00:00:00Z","timestamp":1743033600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T00:00:00Z","timestamp":1743033600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T00:00:00Z","timestamp":1743033600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["18K05337"],"award-info":[{"award-number":["18K05337"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["21K05291"],"award-info":[{"award-number":["21K05291"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Nat. Prod."],"published-print":{"date-parts":[[2025,4,25]]},"DOI":"10.1021\/acs.jnatprod.5c00095","type":"journal-article","created":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T17:47:58Z","timestamp":1743097678000},"page":"1023-1029","source":"Crossref","is-referenced-by-count":5,"title":["Hedopeptolide, a NO Production Inhibitor from the Marine Cyanobacterium <i>Okeania<\/i> sp."],"prefix":"10.1021","volume":"88","author":[{"given":"Shunya","family":"Tojo","sequence":"first","affiliation":[{"name":"Graduate School of Engineering and Science, University of the Ryukyus, 1 Senbaru, Nishihara, Okinawa 903-0213, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriyuki","family":"Natsume","sequence":"additional","affiliation":[{"name":"Graduate School of Engineering and Science, University of the Ryukyus, 1 Senbaru, Nishihara, Okinawa 903-0213, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taiki","family":"Niino","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Life Science, School of Advanced Engineering, Kogakuin University, 2665-1 Nakano-machi, Hachi-oji, Tokyo 192-0015, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3775-5066","authenticated-orcid":true,"given":"Arihiro","family":"Iwasaki","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yoko-hama, Kanagawa 223-8522, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5343-5890","authenticated-orcid":true,"given":"Kiyotake","family":"Suenaga","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yoko-hama, Kanagawa 223-8522, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8147-6857","authenticated-orcid":true,"given":"Osamu","family":"Ohno","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Life Science, School of Advanced Engineering, Kogakuin University, 2665-1 Nakano-machi, Hachi-oji, Tokyo 192-0015, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7018-7734","authenticated-orcid":true,"given":"Toshiaki","family":"Teruya","sequence":"additional","affiliation":[{"name":"Graduate School of Engineering and Science, University of the Ryukyus, 1 Senbaru, Nishihara, Okinawa 903-0213, Japan"},{"name":"Faculty of Education, University of the Ryukyus, 1 Senbaru, Nishihara, Okinawa 903-0213, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2025,3,27]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1039\/D2NP00083K"},{"key":"ref2\/cit2a","doi-asserted-by":"publisher","DOI":"10.1021\/ja00302a042"},{"key":"ref2\/cit2b","doi-asserted-by":"publisher","DOI":"10.1351\/pac198658050701"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1021\/jo00302a007"},{"key":"ref4\/cit4a","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-894X(00)00150-5"},{"key":"ref4\/cit4b","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2004.08.068"},{"key":"ref4\/cit4c","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2004.08.069"},{"key":"ref4\/cit4d","doi-asserted-by":"publisher","DOI":"10.1021\/cr900016w"},{"key":"ref4\/cit4e","doi-asserted-by":"publisher","DOI":"10.2146\/ajhp110237"},{"key":"ref4\/cit4f","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-45001-9"},{"key":"ref5\/cit5a","doi-asserted-by":"publisher","DOI":"10.1021\/ol0062502"},{"key":"ref5\/cit5b","doi-asserted-by":"publisher","DOI":"10.1039\/C4NP00051J"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.hal.2019.05.001"},{"key":"ref7\/cit7a","doi-asserted-by":"publisher","DOI":"10.1021\/ja00256a070"},{"key":"ref7\/cit7b","doi-asserted-by":"publisher","DOI":"10.1021\/np980321c"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/np010049y"},{"key":"ref9\/cit9a","doi-asserted-by":"publisher","DOI":"10.1038\/nbt832"},{"key":"ref9\/cit9b","doi-asserted-by":"publisher","DOI":"10.1038\/nrd3629"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.2289"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.0c00042"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.1c00817"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c04459"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.5b00301"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1107\/S0108767383001762"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1107\/S0021889800007184"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1007\/BF02908688"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/0278-6915(84)90224-2"},{"key":"ref19\/cit19a","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.7b00137"},{"key":"ref19\/cit19b","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2020.127069"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/ja010015c"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(02)01209-1"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1002\/ange.200461239"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/chem.200500624"},{"key":"ref24\/cit24a","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200500702"},{"key":"ref24\/cit24b","doi-asserted-by":"publisher","DOI":"10.1021\/ja060064v"},{"key":"ref25\/cit25a","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2004.06.111"},{"key":"ref25\/cit25b","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2005.12.026"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1002\/chem.200600383"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bts252"},{"key":"ref28\/cit28a","doi-asserted-by":"publisher","DOI":"10.1080\/10635150701472164"},{"key":"ref28\/cit28b","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.molbev.a026334"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2109"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1080\/10635150390235520"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1093\/sysbio\/sys029"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/0300-9084(96)84768-7"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.2144\/19962003390"}],"container-title":["Journal of Natural Products"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jnatprod.5c00095","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jnatprod.5c00095","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T08:11:19Z","timestamp":1745568679000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jnatprod.5c00095"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,27]]},"references-count":46,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4,25]]}},"alternative-id":["10.1021\/acs.jnatprod.5c00095"],"URL":"https:\/\/doi.org\/10.1021\/acs.jnatprod.5c00095","relation":{},"ISSN":["0163-3864","1520-6025"],"issn-type":[{"value":"0163-3864","type":"print"},{"value":"1520-6025","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,27]]}}}