{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T03:59:28Z","timestamp":1791863968940,"version":"4.3.4"},"reference-count":63,"publisher":"American Chemical Society (ACS)","issue":"7","license":[{"start":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T00:00:00Z","timestamp":1752624000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T00:00:00Z","timestamp":1752624000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T00:00:00Z","timestamp":1752624000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100009771","name":"American Society of Pharmacognosy","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009771","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006545","name":"National Institute on Minority Health and Health Disparities","doi-asserted-by":"publisher","award":["U54 MD007600"],"award-info":[{"award-number":["U54 MD007600"]}],"id":[{"id":"10.13039\/100006545","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["3T34GM007821"],"award-info":[{"award-number":["3T34GM007821"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["SC2GM144152"],"award-info":[{"award-number":["SC2GM144152"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Nat. Prod."],"published-print":{"date-parts":[[2025,7,25]]},"DOI":"10.1021\/acs.jnatprod.5c00439","type":"journal-article","created":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T17:36:54Z","timestamp":1752687414000},"page":"1701-1709","source":"Crossref","is-referenced-by-count":1,"title":["In Silico Design and Analysis of Cyanobacterial Pseudo Natural Products"],"prefix":"10.1021","volume":"88","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1039-4790","authenticated-orcid":true,"given":"\u00c1ngel D.","family":"Hern\u00e1ndez-Mej\u00edas","sequence":"first","affiliation":[{"name":"Department of Chemistry","place":["San Juan, United States"]},{"name":"University of Puerto Rico \u2212 Rio Piedras","place":["San Juan, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0343-3235","authenticated-orcid":true,"given":"Gabriel D.","family":"Jimenez-Nieves","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, School of Pharmacy","place":["San Juan, United States"]},{"name":"University of Puerto Rico \u2212 Medical Sciences Campus","place":["San Juan, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2049-6248","authenticated-orcid":true,"given":"Eduardo J. E.","family":"Caro-Diaz","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, School of Pharmacy","place":["San Juan, United States"]},{"name":"University of Puerto Rico \u2212 Medical Sciences Campus","place":["San Juan, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,7,16]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.9b01285"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1039\/D4NP00040D"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1039\/D3NP00045A"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.3390\/md17060320"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.3390\/molecules29225307"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.9b00294"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.1c01494"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-32016-6"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.8b04050"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2016.04.008"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2021847118"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.3c00589"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.7b00671"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202203958"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.4c00441"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/ja00256a070"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/np010049y"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.3390\/md20080494"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.3390\/md15010018"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1248\/cpb.c19-00853"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.3390\/md22120537"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1039\/D3NP00050H"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1039\/D1NP00036E"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1039\/C9MD00128J"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-023-00774-7"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.3390\/md18120640"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-020-00114-z"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1111\/1751-7915.13351"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1614680114"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1126\/science.287.5460.1964"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms1081"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1039\/C8OB02327A"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1515\/bc.2010.013"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-019-0411-x"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202016575"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202002449"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201909518"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.24820\/ark.5550190.p011.348"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.3762\/bjoc.7.191"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2010.02.018"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2018.12.007"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2018.10.024"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1002\/chem.200600599"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1021\/jm100244y"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2011.07.078"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1039\/C6CC03244C"},{"key":"ref47\/cit47","unstructured":"ChemAxon.\n                      Design\nHub\n                      . https:\/\/chemaxon.com\/design-hub (accessed 2025\u201301\u201331)."},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.copbio.2007.10.005"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/ml4004638"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1021\/jm900818s"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1038\/s41570-025-00688-5"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1038\/srep42717"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1186\/s13321-019-0378-z"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1021\/ci700286x"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-13-106"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkad976"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkx1037"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1021\/ci500588j"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1186\/s13321-015-0069-3"},{"key":"ref60\/cit60","unstructured":"RDKit. https:\/\/www.rdkit.org."},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1186\/1758-2946-1-8"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1002\/minf.202200133"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2021.117017"}],"container-title":["Journal of Natural Products"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jnatprod.5c00439","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jnatprod.5c00439","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T08:12:44Z","timestamp":1753431164000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jnatprod.5c00439"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,16]]},"references-count":63,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7,25]]}},"alternative-id":["10.1021\/acs.jnatprod.5c00439"],"URL":"https:\/\/doi.org\/10.1021\/acs.jnatprod.5c00439","relation":{"has-preprint":[{"id-type":"doi","id":"10.26434\/chemrxiv-2025-cs6dz-v2","asserted-by":"object"},{"id-type":"doi","id":"10.26434\/chemrxiv-2025-cs6dz","asserted-by":"object"}]},"ISSN":["0163-3864","1520-6025"],"issn-type":[{"value":"0163-3864","type":"print"},{"value":"1520-6025","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,16]]}}}