{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T01:23:27Z","timestamp":1794360207558,"version":"4.9.0"},"reference-count":53,"publisher":"American Chemical Society (ACS)","issue":"2","license":[{"start":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:00:00Z","timestamp":1768521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:00:00Z","timestamp":1768521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T00:00:00Z","timestamp":1768521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["Y20240158"],"award-info":[{"award-number":["Y20240158"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Visiting Researcher Program, Directorate of Talent Management, National Research and Innovation Agency"},{"name":"CAMS Innovation Fund for Medical Sciences","award":["CIFMS 2021-I2M-1-028"],"award-info":[{"award-number":["CIFMS 2021-I2M-1-028"]}]},{"name":"Research Program House of Research Organization for Life Sciences and Environment"},{"name":"Kunlun Talented People, High-end Innovation and Entrepreneurship Talents Plan of Qinghai Province in 2022"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Nat. Prod."],"published-print":{"date-parts":[[2026,2,27]]},"DOI":"10.1021\/acs.jnatprod.5c01323","type":"journal-article","created":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T17:07:51Z","timestamp":1768583271000},"page":"469-482","source":"Crossref","is-referenced-by-count":1,"title":["Discovery of Antibacterial Piperazic Acid-containing Pseudopeptides from a\n                    <i>Saccharothrix<\/i>\n                    Strain Using Targeted Genetic Screening and Molecular Networking Strategies"],"prefix":"10.1021","volume":"89","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4614-4857","authenticated-orcid":true,"given":"Shaowei","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Microbial Chemistry, Institute of Medicinal Biotechnology","place":["Beijing, China"]},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keke","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Microbial Chemistry, Institute of Medicinal Biotechnology","place":["Beijing, China"]},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiming","family":"Li","sequence":"additional","affiliation":[{"name":"NHC Key Laboratory of Biotechnology for Microbial Drugs, Institute of Medicinal Biotechnology","place":["Beijing, China"]},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Zhang","sequence":"additional","affiliation":[{"name":"NHC Key Laboratory of Biotechnology for Microbial Drugs, Institute of Medicinal Biotechnology","place":["Beijing, China"]},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jixiang","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Microbial Chemistry, Institute of Medicinal Biotechnology","place":["Beijing, China"]},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuyu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Microbial Chemistry, Institute of Medicinal Biotechnology","place":["Beijing, China"]},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongwei","family":"He","sequence":"additional","affiliation":[{"name":"NHC Key Laboratory of Biotechnology for Microbial Drugs, Institute of Medicinal Biotechnology","place":["Beijing, China"]},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1798-4849","authenticated-orcid":true,"given":"Gang","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Microbial Chemistry, Institute of Medicinal Biotechnology","place":["Beijing, China"]},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joko Tri","family":"Wibowo","sequence":"additional","affiliation":[{"name":"Department of Microbial Chemistry, Institute of Medicinal Biotechnology","place":["Beijing, China"]},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Beijing, China"]},{"name":"Research Center for Vaccine and Drugs","place":["Cibinong, Indonesia"]},{"name":"Research Organization for Health, Research and Innovation Agency of Indonesia (BRIN)","place":["Cibinong, Indonesia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ira","family":"Handayani","sequence":"additional","affiliation":[{"name":"Research Center for Applied Microbiology, Research Organization for Life Sciences and Environment","place":["Cibinong, Indonesia"]},{"name":"Research and Innovation Agency of Indonesia (BRIN)","place":["Cibinong, Indonesia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dewi Seswita","family":"Zilda","sequence":"additional","affiliation":[{"name":"Research Center for Applied Microbiology, Research Organization for Life Sciences and Environment","place":["Cibinong, Indonesia"]},{"name":"Research and Innovation Agency of Indonesia (BRIN)","place":["Cibinong, Indonesia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Xiang","sequence":"additional","affiliation":[{"name":"School of Eco-Environmental Engineering","place":["Xining, China"]},{"name":"Qinghai University","place":["Xining, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6813-8274","authenticated-orcid":true,"given":"Chenghang","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Microbial Chemistry, Institute of Medicinal Biotechnology","place":["Beijing, China"]},{"name":"Chinese Academy of Medical Sciences and Peking Union Medical College","place":["Beijing, China"]},{"name":"Research Center for Applied Microbiology, Research Organization for Life Sciences and Environment","place":["Cibinong, Indonesia"]},{"name":"Research and Innovation Agency of Indonesia (BRIN)","place":["Cibinong, Indonesia"]},{"name":"School of Eco-Environmental Engineering","place":["Xining, China"]},{"name":"Qinghai University","place":["Xining, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,1,16]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-024-01141-y"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcat.2023.113733"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1039\/C8NP00076J"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c03660"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1039\/a827437z"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.201200054"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.2411"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25042347"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c04699"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.0c00818"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2117941119"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-021-01197-1"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2025.102584"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28010157"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.4c02230"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz882"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201102305"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.47.1473"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(01)00525-1"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkad344"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-01975-6"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c17876"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5c08076"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-5521(99)80082-9"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-4622(02)00179-5"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/jo035667t"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/ac970289b"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/ac9701795"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/jo991218a"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1038\/195701b0"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.39.1378"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1007\/BF01998972"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.49.811"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0702791104"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M805527200"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaa913"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.2174\/0929867321666140826115734"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2424388122"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.64749-0"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btm404"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msy096"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1080\/10635150490522304"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msn067"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1007\/BF00160154"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1007\/BF01734359"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1007\/BF01731581"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkab301"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1099\/ijsem.0.005906"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btab007"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms11102475"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1101\/gr.1239303"},{"key":"ref52\/cit52","unstructured":"M07\n| Methods for Dilution Antimicrobial Susceptibility Tests for\nBacteria That Grow Aerobically\n                      . https:\/\/clsi.org\/shop\/standards\/m07\/ (accessed April 15, 2025)."},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22136692"}],"container-title":["Journal of Natural Products"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jnatprod.5c01323","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jnatprod.5c01323","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T07:34:46Z","timestamp":1773128086000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jnatprod.5c01323"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,16]]},"references-count":53,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2,27]]}},"alternative-id":["10.1021\/acs.jnatprod.5c01323"],"URL":"https:\/\/doi.org\/10.1021\/acs.jnatprod.5c01323","relation":{"has-part":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1021\/acs.jnatprod.5c01323.s001","asserted-by":"subject"},{"id-type":"doi","id":"https:\/\/doi.org\/10.1021\/acs.jnatprod.5c01323.s002","asserted-by":"subject"}]},"ISSN":["0163-3864","1520-6025"],"issn-type":[{"value":"0163-3864","type":"print"},{"value":"1520-6025","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,16]]}}}