{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:08:07Z","timestamp":1792084087872,"version":"4.4.0"},"reference-count":37,"publisher":"American Chemical Society (ACS)","issue":"3","license":[{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100031478","name":"European Commission","doi-asserted-by":"publisher","award":["IR0000005"],"award-info":[{"award-number":["IR0000005"]}],"id":[{"id":"10.13039\/100031478","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Italian Ministry of University and Research","award":["CN00000033"],"award-info":[{"award-number":["CN00000033"]}]},{"name":"Italian Ministry of University and Research","award":["CUP B83C22002930006"],"award-info":[{"award-number":["CUP B83C22002930006"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Nat. Prod."],"published-print":{"date-parts":[[2026,3,27]]},"DOI":"10.1021\/acs.jnatprod.5c01414","type":"journal-article","created":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:51:31Z","timestamp":1772171491000},"page":"864-872","source":"Crossref","is-referenced-by-count":1,"title":["Gigobolins A\u2013C, New Ophiobolins with Anticancer Activity from the Phytopathogenic Fungus\n                    <i>Drechslera gigantea<\/i>"],"prefix":"10.1021","volume":"89","author":[{"given":"Marianna","family":"Carbone","sequence":"first","affiliation":[{"name":"National Research Council (CNR), Institute of Biomolecular Chemistry, Via Campi Flegrei 34, 80078 Pozzuoli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sridharan","family":"Jayamohan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Texas Health San Antonio, 7703 Floyd Curl Drive, San Antonio, Texas 78229, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amelia","family":"Scott","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, Texas State University, 601 University Dr., San Marcos, Texas 78666, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Boari","sequence":"additional","affiliation":[{"name":"National Research Council, Institute of Sciences of Food Production, Via Amendola 122\/O, 70125 Bari, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan J.","family":"Rutledge","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, Texas State University, 601 University Dr., San Marcos, Texas 78666, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Cacciapuoti","sequence":"additional","affiliation":[{"name":"National Research Council (CNR), Institute of Biomolecular Chemistry, Via Campi Flegrei 34, 80078 Pozzuoli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vamika","family":"Gautam","sequence":"additional","affiliation":[{"name":"Department of Biology, Baylor University, 101 Bagby Ave., Waco, Texas 76798, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaquelin","family":"Aroujo","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, Baylor University, 101 Bagby Ave., Waco, Texas 76798, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2460-6133","authenticated-orcid":true,"given":"Tania","family":"Betancourt","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, Texas State University, 601 University Dr., San Marcos, Texas 78666, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3805-092X","authenticated-orcid":true,"given":"Daniel","family":"Romo","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, Baylor University, 101 Bagby Ave., Waco, Texas 76798, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9977-3932","authenticated-orcid":true,"given":"Gangadhara Reddy","family":"Sareddy","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Texas Health San Antonio, 7703 Floyd Curl Drive, San Antonio, Texas 78229, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph H.","family":"Taube","sequence":"additional","affiliation":[{"name":"Department of Biology, Baylor University, 101 Bagby Ave., Waco, Texas 76798, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2041-7367","authenticated-orcid":true,"given":"Alexander","family":"Kornienko","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, Texas State University, 601 University Dr., San Marcos, Texas 78666, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9110-1656","authenticated-orcid":true,"given":"Antonio","family":"Evidente","sequence":"additional","affiliation":[{"name":"National Research Council (CNR), Institute of Biomolecular Chemistry, Via Campi Flegrei 34, 80078 Pozzuoli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7308-1011","authenticated-orcid":true,"given":"Maria Letizia","family":"Ciavatta","sequence":"additional","affiliation":[{"name":"National Research Council (CNR), Institute of Biomolecular Chemistry, Via Campi Flegrei 34, 80078 Pozzuoli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,2,27]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1271\/nogeikagaku1924.32.10_739"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.7b00335"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2004.05.021"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2006.07.016"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2013.08.002"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/np50059a001"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.7b00137"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.6b00552"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2019.02.007"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/ja00949a061"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.47371\/mycosci.2020.11.002"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(01)96148-4"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2013.04.034"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1080\/09168451.2018.1429890"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.9b00744"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.8354"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.4c00064"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.70975"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.3390\/md17060346"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23031903"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(00)00668-8"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1039\/D3NP00035D"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.3390\/curroncol31070296"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1007\/s12672-025-02567-3"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2013.85"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2024.129863"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/jso.27459"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.03.027"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-89923-9"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2025.130112"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2020.103816"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/0968-0896(96)00036-3"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/np50115a009"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/noad018"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15072008"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.3390\/molecules181214629"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2016.395"}],"container-title":["Journal of Natural Products"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jnatprod.5c01414","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jnatprod.5c01414","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T08:14:05Z","timestamp":1774599245000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jnatprod.5c01414"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,27]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3,27]]}},"alternative-id":["10.1021\/acs.jnatprod.5c01414"],"URL":"https:\/\/doi.org\/10.1021\/acs.jnatprod.5c01414","relation":{},"ISSN":["0163-3864","1520-6025"],"issn-type":[{"value":"0163-3864","type":"print"},{"value":"1520-6025","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,27]]}}}