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The two known cholestane glycosides 1 and 2 and the five new cholestane glycosides galtonosides A\u2013E (3\u20137) were isolated after bioassay-directed fractionation. The structures of the new compounds were determined by interpretation of their NMR and mass spectra. Among these compounds, galtonoside B (4) displayed the most potent antiplasmodial activity, with an IC50 value of 0.214 \u03bcM against the drug-resistant Dd2 strain of Plasmodium falciparum.<\/jats:p>","DOI":"10.1021\/acs.jnatprod.9b01064","type":"journal-article","created":{"date-parts":[[2020,3,31]],"date-time":"2020-03-31T14:22:07Z","timestamp":1585664527000},"page":"1043-1050","source":"Crossref","is-referenced-by-count":8,"title":["Galtonosides A\u2013E: Antiproliferative and Antiplasmodial\nCholestane Glycosides from\n                    <i>Galtonia regalis<\/i>"],"prefix":"10.1021","volume":"83","author":[{"given":"Yongle","family":"Du","sequence":"first","affiliation":[{"name":"Virginia Tech , , , ,","place":["Blacksburg, Virginia, United States, 24061"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brooke A.","family":"Martin","sequence":"additional","affiliation":[{"name":"Virginia Tech , , , ,","place":["Blacksburg, Virginia, United States, 24061"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Lisa","family":"Valenciano","sequence":"additional","affiliation":[{"name":"University of Georgia , , , ,","place":["Athens, Georgia, United States, 30602"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason A.","family":"Clement","sequence":"additional","affiliation":[{"name":"Baruch S. 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