{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T23:17:38Z","timestamp":1788391058733,"version":"build-2803163510"},"reference-count":48,"publisher":"American Chemical Society (ACS)","issue":"9","license":[{"start":{"date-parts":[[2020,4,14]],"date-time":"2020-04-14T00:00:00Z","timestamp":1586822400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/pubs.acs.org\/page\/policy\/authorchoice_ccby_termsofuse.html"}],"funder":[{"DOI":"10.13039\/501100000266","name":"Engineering and Physical Sciences Research Council","doi-asserted-by":"publisher","award":["EP\/K024205\/1"],"award-info":[{"award-number":["EP\/K024205\/1"]}],"id":[{"id":"10.13039\/501100000266","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We report the synthesis of sulfinamides using organometallic reagents, a sulfur dioxide reagent, and nitrogen based-nucleophiles. The addition of an organometallic reagent to the commercially available sulfur dioxide surrogate, DABSO, generates a metal sulfinate which is reacted with thionyl chloride to form a sulfinyl chloride intermediate. Trapping the sulfinyl chlorides in situ with a variety of nitrogen nucleophiles delivers sulfinamides in 32\u201383% yields. Each stage of the process is performed at room temperature, and the total reaction time is only 1.5 h.<\/jats:p>","DOI":"10.1021\/acs.joc.0c00334","type":"journal-article","created":{"date-parts":[[2020,4,14]],"date-time":"2020-04-14T14:19:18Z","timestamp":1586873958000},"page":"5753-5760","source":"Crossref","is-referenced-by-count":54,"title":["Sulfinamide Synthesis Using Organometallic Reagents,\nDABSO, and Amines"],"prefix":"10.1021","volume":"85","author":[{"given":"Pui Kin Tony","family":"Lo","sequence":"first","affiliation":[{"name":"University of Oxford , , Mansfield Road , ,","place":["Oxford, United Kingdom, OX1 3TA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwyndaf A.","family":"Oliver","sequence":"additional","affiliation":[{"name":"University of Oxford , , Mansfield Road , ,","place":["Oxford, United Kingdom, OX1 3TA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0636-6471","authenticated-orcid":true,"given":"Michael C.","family":"Willis","sequence":"additional","affiliation":[{"name":"University of Oxford , , Mansfield Road , ,","place":["Oxford, United Kingdom, OX1 3TA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2020,4,14]]},"reference":[{"key":"2026090218451285000_cit1a","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1021\/ar020066u","article-title":"N-tert-Butanesulfinyl Imines:\u2009 Versatile Intermediates for the Asymmetric\nSynthesis of Amines","volume":"35","author":"Ellman","year":"2002","journal-title":"Acc. 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Chem."}],"container-title":["The Journal of Organic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.joc.0c00334","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/joceah\/article-pdf\/85\/9\/5753\/67040625\/acs.joc.0c00334.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/joceah\/article-pdf\/85\/9\/5753\/67040625\/acs.joc.0c00334.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T22:45:20Z","timestamp":1788389120000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/joceah\/article\/85\/9\/5753\/1330455\/Sulfinamide-Synthesis-Using-Organometallic"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,14]]},"references-count":48,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2020,4,14]]},"published-print":{"date-parts":[[2020,5,1]]}},"URL":"https:\/\/doi.org\/10.1021\/acs.joc.0c00334","relation":{},"ISSN":["0022-3263","1520-6904"],"issn-type":[{"value":"0022-3263","type":"print"},{"value":"1520-6904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,14]]}}}