{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T10:00:24Z","timestamp":1777024824890,"version":"3.51.4"},"reference-count":85,"publisher":"American Chemical Society (ACS)","issue":"11","license":[{"start":{"date-parts":[[2021,5,17]],"date-time":"2021-05-17T00:00:00Z","timestamp":1621209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,5,17]],"date-time":"2021-05-17T00:00:00Z","timestamp":1621209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,5,17]],"date-time":"2021-05-17T00:00:00Z","timestamp":1621209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21901074"],"award-info":[{"award-number":["21901074"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81660576"],"award-info":[{"award-number":["81660576"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Org. Chem."],"published-print":{"date-parts":[[2021,6,4]]},"DOI":"10.1021\/acs.joc.1c00570","type":"journal-article","created":{"date-parts":[[2021,5,17]],"date-time":"2021-05-17T21:41:46Z","timestamp":1621287706000},"page":"7797-7805","source":"Crossref","is-referenced-by-count":15,"title":["Construction of <i>gem<\/i>-Difluoroenol Esters through Catalytic <i>O<\/i>-Selective Addition of Difluoroenoxysilanes to Ketenes"],"prefix":"10.1021","volume":"86","author":[{"given":"Yang","family":"Shi","sequence":"first","affiliation":[{"name":"College of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang 550025, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo-Wen","family":"Pan","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang 550025, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun-Xiong","family":"He","sequence":"additional","affiliation":[{"name":"Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Zhou","sequence":"additional","affiliation":[{"name":"College of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang 550025, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0679-6735","authenticated-orcid":true,"given":"Jian","family":"Zhou","sequence":"additional","affiliation":[{"name":"Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China"},{"name":"State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Shanghai 200032, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0619-2037","authenticated-orcid":true,"given":"Jin-Sheng","family":"Yu","sequence":"additional","affiliation":[{"name":"Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2021,5,17]]},"reference":[{"key":"ref1\/cit1a","doi-asserted-by":"crossref","DOI":"10.1002\/9780470281895","volume-title":"Bioorganic and Medicinal Chemistry of Fluorine","author":"B\u00e9gu\u00e9 J.-P.","year":"2008"},{"key":"ref1\/cit1b","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.200300829"},{"key":"ref2\/cit2a","doi-asserted-by":"crossref","DOI":"10.1002\/9781444312096","volume-title":"Fluorine in Medicinal Chemistry and Chemical Biology","author":"Ojima I.","year":"2009"},{"key":"ref2\/cit2b","doi-asserted-by":"publisher","DOI":"10.1126\/science.1131943"},{"key":"ref2\/cit2c","doi-asserted-by":"publisher","DOI":"10.1039\/B711844A"},{"key":"ref2\/cit2d","doi-asserted-by":"publisher","DOI":"10.1039\/B610213C"},{"key":"ref2\/cit2e","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201206566"},{"key":"ref2\/cit2f","doi-asserted-by":"publisher","DOI":"10.1021\/cr4002879"},{"key":"ref2\/cit2g","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.7b01788"},{"key":"ref3\/cit3a","doi-asserted-by":"publisher","DOI":"10.1021\/jm034162s"},{"key":"ref3\/cit3b","doi-asserted-by":"publisher","DOI":"10.1021\/jm900321u"},{"key":"ref3\/cit3c","doi-asserted-by":"publisher","DOI":"10.1021\/jm00391a036"},{"key":"ref3\/cit3d","unstructured":"dFujii, K.; Nakamoto, Y.; Hatano, K.; Kanetsuki, Y. JP 2006016331A, 2006."},{"key":"ref3\/cit3e","doi-asserted-by":"publisher","DOI":"10.1021\/jm0495982"},{"key":"ref3\/cit3f","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfluchem.2005.12.013"},{"key":"ref4\/cit4a","doi-asserted-by":"publisher","DOI":"10.1021\/cr800388c"},{"key":"ref4\/cit4b","doi-asserted-by":"publisher","DOI":"10.1039\/D0CC04318D"},{"key":"ref5\/cit5a","doi-asserted-by":"publisher","DOI":"10.1021\/cr200165q"},{"key":"ref5\/cit5b","doi-asserted-by":"publisher","DOI":"10.1021\/cr941140s"},{"key":"ref5\/cit5c","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-1139(99)00268-7"},{"key":"ref5\/cit5d","doi-asserted-by":"publisher","DOI":"10.1016\/0040-4020(96)00311-0"},{"key":"ref5\/cit5e","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2016.12.054"},{"key":"ref5\/cit5f","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201805292"},{"key":"ref5\/cit5g","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201801702"},{"key":"ref6\/cit6a","doi-asserted-by":"publisher","DOI":"10.1039\/a903681d"},{"key":"ref6\/cit6b","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-1139(01)00535-8"},{"key":"ref7\/cit7a","doi-asserted-by":"publisher","DOI":"10.1039\/C9CC07677H"},{"key":"ref7\/cit7b","doi-asserted-by":"publisher","DOI":"10.1039\/C5OB00855G"},{"key":"ref8\/cit8a","doi-asserted-by":"publisher","DOI":"10.1021\/jo001549j"},{"key":"ref8\/cit8b","doi-asserted-by":"publisher","DOI":"10.1021\/jo0158579"},{"key":"ref8\/cit8c","doi-asserted-by":"publisher","DOI":"10.1039\/c2cc17140f"},{"key":"ref8\/cit8d","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201404432"},{"key":"ref8\/cit8e","doi-asserted-by":"publisher","DOI":"10.1016\/j.scib.2017.10.016"},{"key":"ref8\/cit8f","doi-asserted-by":"publisher","DOI":"10.1039\/C9OB02129A"},{"key":"ref9\/cit9a","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(98)00224-5"},{"key":"ref9\/cit9b","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200601808"},{"key":"ref9\/cit9c","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201501747"},{"key":"ref9\/cit9d","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2018.11.017"},{"key":"ref10\/cit10a","doi-asserted-by":"publisher","DOI":"10.1021\/ol049055m"},{"key":"ref10\/cit10b","doi-asserted-by":"publisher","DOI":"10.1021\/om1000259"},{"key":"ref10\/cit10c","doi-asserted-by":"publisher","DOI":"10.1039\/C6CC00177G"},{"key":"ref10\/cit10d","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201900745"},{"key":"ref10\/cit10e","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.0c02997"},{"key":"ref10\/cit10f","doi-asserted-by":"publisher","DOI":"10.1039\/D0CC05725H"},{"key":"ref11\/cit11a","doi-asserted-by":"publisher","DOI":"10.1002\/ejoc.200500106"},{"key":"ref11\/cit11b","doi-asserted-by":"publisher","DOI":"10.1021\/ol900541n"},{"key":"ref11\/cit11c","doi-asserted-by":"publisher","DOI":"10.1002\/cjoc.201090289"},{"key":"ref11\/cit11d","doi-asserted-by":"publisher","DOI":"10.1021\/ol200374m"},{"key":"ref11\/cit11e","doi-asserted-by":"publisher","DOI":"10.1039\/C5OB01895A"},{"key":"ref11\/cit11f","doi-asserted-by":"publisher","DOI":"10.1039\/C5QO00407A"},{"key":"ref11\/cit11g","doi-asserted-by":"publisher","DOI":"10.1039\/C9QO00577C"},{"key":"ref11\/cit11h","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.7b03213"},{"key":"ref11\/cit11i","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.0c03406"},{"key":"ref11\/cit11j","doi-asserted-by":"publisher","DOI":"10.1039\/C8OB02843E"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201611625"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2019.09.012"},{"key":"ref14\/cit14a","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.0c00018"},{"key":"ref14\/cit14b","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.0c03123"},{"key":"ref14\/cit14c","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-19387-4"},{"key":"ref14\/cit14d","doi-asserted-by":"publisher","DOI":"10.1039\/D0CC06980A"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1002\/ejoc.201800532"},{"key":"ref16\/cit16a","volume-title":"Ketenes II","author":"Tidwell T. T.","year":"2006","edition":"2"},{"key":"ref16\/cit16b","volume-title":"Three Carbon-Heteroatom Bonds: Ketenes and Derivatives","author":"Curt W.","year":"2006"},{"key":"ref16\/cit16c","doi-asserted-by":"publisher","DOI":"10.1021\/cr00087a005"},{"key":"ref16\/cit16d","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200500098"},{"key":"ref16\/cit16e","doi-asserted-by":"publisher","DOI":"10.1021\/cr3005263"},{"key":"ref17\/cit17","volume-title":"Organic Syntheses Based on Name Reactions","author":"Hassner A.","year":"2012","edition":"3"},{"key":"ref18\/cit18a","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(00)82014-6"},{"key":"ref18\/cit18b","doi-asserted-by":"publisher","DOI":"10.1021\/jo00298a047"},{"key":"ref19\/cit19a","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-20725-9"},{"key":"ref19\/cit19b","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfluchem.2007.03.004"},{"key":"ref19\/cit19c","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfluchem.2016.10.017"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.9b00604"},{"key":"ref21\/cit21a","doi-asserted-by":"publisher","DOI":"10.1002\/chem.200305407"},{"key":"ref21\/cit21b","doi-asserted-by":"publisher","DOI":"10.1021\/ol061174+"},{"key":"ref21\/cit21c","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2018.11.006"},{"key":"ref21\/cit21d","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.8b04444"},{"key":"ref23\/cit23a","doi-asserted-by":"publisher","DOI":"10.1039\/C6CS00351F"},{"key":"ref23\/cit23b","doi-asserted-by":"publisher","DOI":"10.1039\/C7CC02341C"},{"key":"ref23\/cit23c","doi-asserted-by":"publisher","DOI":"10.6023\/A18080360"},{"key":"ref24\/cit24a","doi-asserted-by":"publisher","DOI":"10.1021\/ja00305a012"},{"key":"ref24\/cit24b","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.200800532"},{"key":"ref24\/cit24c","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201503308"},{"key":"ref24\/cit24d","doi-asserted-by":"publisher","DOI":"10.1021\/ol300982f"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/ejoc.201403361"}],"container-title":["The Journal of Organic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.joc.1c00570","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T00:08:28Z","timestamp":1682467708000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.joc.1c00570"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,17]]},"references-count":85,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,6,4]]}},"alternative-id":["10.1021\/acs.joc.1c00570"],"URL":"https:\/\/doi.org\/10.1021\/acs.joc.1c00570","relation":{},"ISSN":["0022-3263","1520-6904"],"issn-type":[{"value":"0022-3263","type":"print"},{"value":"1520-6904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,17]]}}}