{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T00:36:15Z","timestamp":1776731775110,"version":"3.51.2"},"reference-count":43,"publisher":"American Chemical Society (ACS)","issue":"16","license":[{"start":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T00:00:00Z","timestamp":1744761600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005057","name":"National Tsing Hua University","doi-asserted-by":"publisher","award":["112QI055E1"],"award-info":[{"award-number":["112QI055E1"]}],"id":[{"id":"10.13039\/501100005057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020950","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["111-2634-F-007-023"],"award-info":[{"award-number":["111-2634-F-007-023"]}],"id":[{"id":"10.13039\/501100020950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020950","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["112-2113-M-007-001"],"award-info":[{"award-number":["112-2113-M-007-001"]}],"id":[{"id":"10.13039\/501100020950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010002","name":"Ministry of Education Republic of China Taiwan","doi-asserted-by":"crossref","award":["110QR001I5"],"award-info":[{"award-number":["110QR001I5"]}],"id":[{"id":"10.13039\/100010002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100010002","name":"Ministry of Education Republic of China Taiwan","doi-asserted-by":"crossref","award":["111QR001I5"],"award-info":[{"award-number":["111QR001I5"]}],"id":[{"id":"10.13039\/100010002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Org. Chem."],"published-print":{"date-parts":[[2025,4,25]]},"DOI":"10.1021\/acs.joc.4c02340","type":"journal-article","created":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:23:51Z","timestamp":1744849431000},"page":"5343-5348","source":"Crossref","is-referenced-by-count":1,"title":["Calcium Impregnated Silica Gel in the Domino Reaction Involving Irreversible Aldol Addition, Dehydration, and Michael Addition"],"prefix":"10.1021","volume":"90","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9225-8484","authenticated-orcid":true,"given":"Jih Ru","family":"Hwu","sequence":"first","affiliation":[{"name":"Department of Chemistry and Frontier Research Center on Fundamental and Applied Sciences of Matters","place":["Hsinchu, Taiwan"]},{"name":"National Tsing Hua University","place":["Hsinchu, Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khagendra Prasad","family":"Bohara","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Frontier Research Center on Fundamental and Applied Sciences of Matters","place":["Hsinchu, Taiwan"]},{"name":"National Tsing Hua University","place":["Hsinchu, Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Animesh","family":"Roy","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Frontier Research Center on Fundamental and Applied Sciences of Matters","place":["Hsinchu, Taiwan"]},{"name":"National Tsing Hua University","place":["Hsinchu, Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Chieh","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Frontier Research Center on Fundamental and Applied Sciences of Matters","place":["Hsinchu, Taiwan"]},{"name":"National Tsing Hua University","place":["Hsinchu, Taiwan"]},{"name":"Institute of Biotechnology and Pharmaceutical Research","place":["Miaoli County, Taiwan"]},{"name":"National Health Research Institutes","place":["Miaoli County, Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1814-9869","authenticated-orcid":true,"given":"Kuo-Chu","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Frontier Research Center on Fundamental and Applied Sciences of Matters","place":["Hsinchu, Taiwan"]},{"name":"National Tsing Hua University","place":["Hsinchu, Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2323-0920","authenticated-orcid":true,"given":"Chun-Cheng","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Frontier Research Center on Fundamental and Applied Sciences of Matters","place":["Hsinchu, Taiwan"]},{"name":"National Tsing Hua University","place":["Hsinchu, Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kao Shu","family":"Chuang","sequence":"additional","affiliation":[{"name":"Department of Green Material Technology","place":["Kaohsiung City, Taiwan"]},{"name":"Green Technology Research Institute, CPC Corporation","place":["Kaohsiung City, Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu-Yu","family":"Lin","sequence":"additional","affiliation":[{"name":"Institute of Biotechnology and Pharmaceutical Research","place":["Miaoli County, Taiwan"]},{"name":"National Health Research Institutes","place":["Miaoli County, Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shwu-Chen","family":"Tsay","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Frontier Research Center on Fundamental and Applied Sciences of Matters","place":["Hsinchu, Taiwan"]},{"name":"National Tsing Hua University","place":["Hsinchu, Taiwan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2025,4,16]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-662-39510-3","volume-title":"Advanced Organic Chemistry Part B: Reactions and Synthesis","author":"Carey F. A.","year":"2001","edition":"6"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1002\/0471264180.or016.01"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.6b00959"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1002\/0471264180.or028.03"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-3765(19990702)5:7<1959::AID-CHEM1959>3.3.CO;2-Z"},{"key":"ref11\/cit11","doi-asserted-by":"crossref","unstructured":"Vrana, L. M. Calcium and Calcium Alloys. Kirk-Othmer Encyclopedia of Chemical Technology; John Wiley & Sons, Inc., 2011; pp. 1\u201310.","DOI":"10.1002\/0471238961.0301120308090202.a01.pub3"},{"key":"ref12\/cit12","first-page":"483","volume-title":"Ullmann\u2019s Encyclopedia of Industrial Chemistry","author":"Hluchan S. E.","year":"2006"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/3527602607.ch4","volume-title":"Main Group Metals in Organic Synthesis","author":"Hwu J. R.","year":"2004"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/jo951219c"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/jo00399a052"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/ja001825b"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1039\/C1SC00724F"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1039\/C1SC00661D"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1039\/c3gc41403e"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1039\/C9CS00615J"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/ol402213k"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1039\/C5RA08682E"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1078445"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1039\/c2ee21779a"},{"key":"ref20\/cit20a","unstructured":"aFile no. 23-0430\nfor Ca metal."},{"key":"ref20\/cit20b","unstructured":"bFile\nno. 46-1045 for SiO2."},{"key":"ref20\/cit20c","unstructured":"cFile no. 65-2384 for CaH2."},{"key":"ref20\/cit20d","unstructured":"dFile no. 17-0912 for CaO."},{"key":"ref21\/cit21a","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2012.01.024"},{"key":"ref21\/cit21b","doi-asserted-by":"publisher","DOI":"10.1007\/s00339-018-1756-5"},{"key":"ref21\/cit21c","doi-asserted-by":"publisher","DOI":"10.1039\/b406392a"},{"key":"ref21\/cit21d","doi-asserted-by":"publisher","DOI":"10.1590\/S1516-14392014005000085"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.3390\/nano10050996"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbon.2017.03.056"},{"key":"ref24\/cit24","volume-title":"Chemical Principles","author":"Zumdahl S. S.","year":"1998","edition":"3"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1038\/srep36225"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.8b00201"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/asia.201500326"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/ar2000698"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/jo970445e"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201404440"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/asia.201901169"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/ol061634z"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202014876"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0804348105"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1351\/pac200072071233"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/ja003629a"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1039\/B918763B"}],"container-title":["The Journal of Organic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.joc.4c02340","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.joc.4c02340","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T08:12:16Z","timestamp":1745568736000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.joc.4c02340"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,16]]},"references-count":43,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2025,4,25]]}},"alternative-id":["10.1021\/acs.joc.4c02340"],"URL":"https:\/\/doi.org\/10.1021\/acs.joc.4c02340","relation":{},"ISSN":["0022-3263","1520-6904"],"issn-type":[{"value":"0022-3263","type":"print"},{"value":"1520-6904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,16]]}}}