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This reaction does not require transition metal catalysts, utilizes oxygen from the air as an oxidant, and is performed at room temperature. Notably, the lignin \u03b2-O-4 model compounds can be directly converted into a variety of quinolines by using this method. Mechanistic studies reveal that the reaction proceeds through a cascade of dehydrogenation, aldol condensation, and ketoamine condensation.<\/jats:p>","DOI":"10.1021\/acs.joc.5c00444","type":"journal-article","created":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:48:02Z","timestamp":1763038082000},"page":"16671-16678","source":"Crossref","is-referenced-by-count":1,"title":["Dehydrogenative\nCyclization of 2-Aminobenzyl\nAlcohols with Ketones or Secondary Alcohols to Construct Quinolines"],"prefix":"10.1021","volume":"90","author":[{"given":"Xiaoyu","family":"Ren","sequence":"first","affiliation":[{"name":"Ministry of Education Taiyuan University of Technology , , ,","place":["Taiyuan, People\u2019s Republic of China, 030024"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Tan","sequence":"additional","affiliation":[{"name":"Jinan University , , ,","place":["Guangzhou, People\u2019s Republic of China, 510632"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2235-6070","authenticated-orcid":true,"given":"Cong-Ying","family":"Zhou","sequence":"additional","affiliation":[{"name":"Jinan University , , ,","place":["Guangzhou, People\u2019s Republic of China, 510632"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9528-1383","authenticated-orcid":true,"given":"Zhen","family":"Guo","sequence":"additional","affiliation":[{"name":"Ministry of Education Taiyuan University of Technology , , ,","place":["Taiyuan, People\u2019s Republic of China, 030024"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,11,13]]},"reference":[{"key":"2026090713225155500_cit1","doi-asserted-by":"publisher","first-page":"5057","DOI":"10.1021\/acs.chemrev.8b00567","article-title":"Progress in the Chemistry of Tetrahydroquinolines","volume":"119","author":"Muthukrishnan","year":"2019","journal-title":"Chem. 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