{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T23:09:12Z","timestamp":1785193752438,"version":"3.55.0"},"reference-count":45,"publisher":"American Chemical Society (ACS)","issue":"25","license":[{"start":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T00:00:00Z","timestamp":1749772800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T00:00:00Z","timestamp":1749772800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T00:00:00Z","timestamp":1749772800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82104019"],"award-info":[{"award-number":["82104019"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Org. Chem."],"published-print":{"date-parts":[[2025,6,27]]},"DOI":"10.1021\/acs.joc.5c00859","type":"journal-article","created":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T13:10:13Z","timestamp":1749820213000},"page":"8737-8744","source":"Crossref","is-referenced-by-count":4,"title":["Biomimetic Synthesis of Myrtucommulones D\u2013E"],"prefix":"10.1021","volume":"90","author":[{"given":"Hong","family":"Guo","sequence":"first","affiliation":[{"name":"State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]},{"name":"Center for Bioactive Natural Molecules and Innovative Drugs, and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Fang","family":"Qi","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]},{"name":"Center for Bioactive Natural Molecules and Innovative Drugs, and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si-Si","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]},{"name":"Center for Bioactive Natural Molecules and Innovative Drugs, and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-Hang","family":"Zhu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]},{"name":"Center for Bioactive Natural Molecules and Innovative Drugs, and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi-Lin","family":"Lin","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]},{"name":"Center for Bioactive Natural Molecules and Innovative Drugs, and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-Qi","family":"Zheng","sequence":"additional","affiliation":[{"name":"Center for Bioactive Natural Molecules and Innovative Drugs, and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-Yi","family":"Wu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]},{"name":"Center for Bioactive Natural Molecules and Innovative Drugs, and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-Xia","family":"Hu","sequence":"additional","affiliation":[{"name":"Center for Bioactive Natural Molecules and Innovative Drugs, and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4344-0498","authenticated-orcid":true,"given":"Chuang-Chuang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Shenzhen Grubbs Institute","place":["Shenzhen, P. R. China"]},{"name":"Southern University of Science and Technology","place":["Shenzhen, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9242-1109","authenticated-orcid":true,"given":"Lei","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]},{"name":"Center for Bioactive Natural Molecules and Innovative Drugs, and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]},{"name":"Guangdong-Hong Kong-Macau Joint Laboratory for Pharmacodynamic Constituents of TCM and New Drugs Research","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min-Jing","family":"Cheng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]},{"name":"Center for Bioactive Natural Molecules and Innovative Drugs, and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]},{"name":"Guangdong-Hong Kong-Macau Joint Laboratory for Pharmacodynamic Constituents of TCM and New Drugs Research","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2810-1001","authenticated-orcid":true,"given":"Wen-Cai","family":"Ye","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Bioactive Molecules and Druggability Assessment, Guangdong Basic Research Center of Excellence for Natural Bioactive Molecules and Discovery of Innovative Drugs","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]},{"name":"Center for Bioactive Natural Molecules and Innovative Drugs, and Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, College of Pharmacy","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]},{"name":"Guangdong-Hong Kong-Macau Joint Laboratory for Pharmacodynamic Constituents of TCM and New Drugs Research","place":["Guangzhou, P. R. China"]},{"name":"Jinan University","place":["Guangzhou, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,6,13]]},"reference":[{"key":"ref1\/cit1b","doi-asserted-by":"publisher","DOI":"10.1039\/c3np20122h"},{"key":"ref1\/cit1c","doi-asserted-by":"publisher","DOI":"10.3390\/molecules23123370"},{"key":"ref1\/cit1d","doi-asserted-by":"publisher","DOI":"10.1039\/D2NP00046F"},{"key":"ref1\/cit1e","doi-asserted-by":"publisher","DOI":"10.2174\/1573406419666221226093311"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1002\/ejoc.200500936"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.202000292"},{"key":"ref4\/cit4b","doi-asserted-by":"publisher","DOI":"10.1021\/np800247u"},{"key":"ref4\/cit4c","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2008.09.054"},{"key":"ref4\/cit4d","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2013.05.085"},{"key":"ref4\/cit4e","doi-asserted-by":"publisher","DOI":"10.1021\/ol4002976"},{"key":"ref4\/cit4f","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.202000292"},{"key":"ref4\/cit4g","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2021.112890"},{"key":"ref5\/cit5a","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200903906"},{"key":"ref5\/cit5b","doi-asserted-by":"publisher","DOI":"10.1021\/ja204040k"},{"key":"ref5\/cit5c","doi-asserted-by":"publisher","DOI":"10.1021\/ja203642n"},{"key":"ref5\/cit5d","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201205837"},{"key":"ref5\/cit5e","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.2173"},{"key":"ref5\/cit5f","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b05484"},{"key":"ref5\/cit5g","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b03110"},{"key":"ref5\/cit5h","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.8b00901"},{"key":"ref5\/cit5i","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-08241-3"},{"key":"ref5\/cit5j","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201915787"},{"key":"ref5\/cit5k","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c13864"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1080\/10286020.2015.1121997"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2022.114445"},{"key":"ref8\/cit8","unstructured":"Gervais, A. Studies toward the Total Synthesis of Tetramethyldihydroxanthene Natural Products; Boston University, 2014; pp 57\u201360."},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-49629-8"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202420671"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202312568"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1039\/jr9650003690"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1270955"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.9b00108"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/np010441b"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2017.11.044"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(01)97486-1"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-1026(199611)11:6<361::AID-FFJ591>3.0.CO;2-T"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1039\/C7SC04672C"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/ejoc.201700887"},{"key":"ref21\/cit21b","doi-asserted-by":"publisher","DOI":"10.2174\/1871520620666200318094138"},{"key":"ref21\/cit21c","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.3c05695"},{"key":"ref21\/cit21d","doi-asserted-by":"publisher","DOI":"10.2174\/1573406419666221226093311"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24121"},{"key":"ref23\/cit23b","doi-asserted-by":"publisher","DOI":"10.1038\/nature17153"},{"key":"ref23\/cit23c","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b01734"},{"key":"ref23\/cit23d","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1038\/s41586-023-06535-1","volume":"622","author":"Tang J.","year":"2023","journal-title":"Nature"}],"container-title":["The Journal of Organic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.joc.5c00859","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.joc.5c00859","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T08:11:33Z","timestamp":1751011893000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.joc.5c00859"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,13]]},"references-count":45,"journal-issue":{"issue":"25","published-print":{"date-parts":[[2025,6,27]]}},"alternative-id":["10.1021\/acs.joc.5c00859"],"URL":"https:\/\/doi.org\/10.1021\/acs.joc.5c00859","relation":{},"ISSN":["0022-3263","1520-6904"],"issn-type":[{"value":"0022-3263","type":"print"},{"value":"1520-6904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,13]]}}}