{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T01:24:11Z","timestamp":1789089851255,"version":"build-2803163510"},"reference-count":37,"publisher":"American Chemical Society (ACS)","issue":"7","license":[{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22494691"],"award-info":[{"award-number":["22494691"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82293685"],"award-info":[{"award-number":["82293685"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82322064"],"award-info":[{"award-number":["82322064"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["XDB0830000"],"award-info":[{"award-number":["XDB0830000"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Org. Chem."],"published-print":{"date-parts":[[2026,2,20]]},"DOI":"10.1021\/acs.joc.5c03053","type":"journal-article","created":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T14:48:14Z","timestamp":1770648494000},"page":"2915-2927","source":"Crossref","is-referenced-by-count":4,"title":["Harperoids A\u2013F, Complex Polyprenylated Acylphloroglucinols from\n                    <i>Harrisonia perforata<\/i>\n                    that Reverse Multidrug Resistance by Targeting ABC Transporter Function"],"prefix":"10.1021","volume":"91","author":[{"given":"Pei-Pei","family":"An","sequence":"first","affiliation":[{"name":"State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering","place":["Lanzhou, China"]},{"name":"Lanzhou University","place":["Lanzhou, China"]},{"name":"State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica","place":["Shanghai, China"]},{"name":"Chinese Academy of Sciences","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Li","sequence":"additional","affiliation":[{"name":"Shandong Laboratory of Yantai Drug Discovery","place":["Yantai, China"]},{"name":"Bohai Rim Advanced Research Institute for Drug Discovery","place":["Yantai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4104-3168","authenticated-orcid":true,"given":"Jin-Hai","family":"Yu","sequence":"additional","affiliation":[{"name":"Shandong Laboratory of Yantai Drug Discovery","place":["Yantai, China"]},{"name":"Bohai Rim Advanced Research Institute for Drug Discovery","place":["Yantai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9000-5320","authenticated-orcid":true,"given":"Bin","family":"Zhou","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica","place":["Shanghai, China"]},{"name":"Chinese Academy of Sciences","place":["Shanghai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4053-4870","authenticated-orcid":true,"given":"Jian-Min","family":"Yue","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering","place":["Lanzhou, China"]},{"name":"Lanzhou University","place":["Lanzhou, China"]},{"name":"State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica","place":["Shanghai, China"]},{"name":"Chinese Academy of Sciences","place":["Shanghai, China"]},{"name":"Shandong Laboratory of Yantai Drug Discovery","place":["Yantai, China"]},{"name":"Bohai Rim Advanced Research Institute for Drug Discovery","place":["Yantai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,2,9]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00551"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2020.04.028"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1039\/C6QO00620E"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2024.109859"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.5c00605"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2024.110478"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2024.107145"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2024.107657"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c07007"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-48879-w"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2008.11.068"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.0c03460"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201602783"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201412126"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytol.2022.04.003"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-020-0933-6"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.phytochem.2022.113482"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.8b03445"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1007\/s13659-014-0007-5"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2020.104678"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.4c04135"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2022.114532"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2024.107739"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.2c00971"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.3c01920"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1126\/science.aav7102"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2021.166980"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.4c04798"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2025.465912"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.4c12108"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.eng.2023.09.015"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2023.05.001"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.0c00337"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2021.113336"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jnatprod.0c00334"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.drup.2024.101100"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.1c01452"}],"container-title":["The Journal of Organic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.joc.5c03053","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.joc.5c03053","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T08:58:03Z","timestamp":1773133083000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.joc.5c03053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,9]]},"references-count":37,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,2,20]]}},"alternative-id":["10.1021\/acs.joc.5c03053"],"URL":"https:\/\/doi.org\/10.1021\/acs.joc.5c03053","relation":{},"ISSN":["0022-3263","1520-6904"],"issn-type":[{"value":"0022-3263","type":"print"},{"value":"1520-6904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,9]]}}}