{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T12:55:15Z","timestamp":1792500915370,"version":"4.5.0"},"reference-count":39,"publisher":"American Chemical Society (ACS)","license":[{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22371297"],"award-info":[{"award-number":["22371297"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Org. Chem."],"DOI":"10.1021\/acs.joc.6c00614","type":"journal-article","created":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:08:57Z","timestamp":1777939737000},"source":"Crossref","is-referenced-by-count":1,"title":["Enantioselective Synthesis of Dihydropyridione-Fused Uracils by N-Heterocyclic Carbene Organocatalysis"],"prefix":"10.1021","author":[{"given":"Xiyun","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Chemistry, School of Science","place":["Nanjing, P. R. China"]},{"name":"China Pharmaceutical University","place":["Nanjing, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhao","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Chemistry, School of Science","place":["Nanjing, P. R. China"]},{"name":"China Pharmaceutical University","place":["Nanjing, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lanhao","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Chemistry, School of Science","place":["Nanjing, P. R. China"]},{"name":"China Pharmaceutical University","place":["Nanjing, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Chemistry, School of Science","place":["Nanjing, P. R. China"]},{"name":"China Pharmaceutical University","place":["Nanjing, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4615-5433","authenticated-orcid":true,"given":"Ding","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Chemistry, School of Science","place":["Nanjing, P. R. China"]},{"name":"China Pharmaceutical University","place":["Nanjing, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,5,4]]},"reference":[{"key":"ref1\/cit1","unstructured":"Scott, G. D. Method using lifespan-altering compounds for altering the lifespan of eukaryotic organisms, and screening for such compounds. WO Patent WO2009086303A3"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.6b01336"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1039\/c3ob42132e"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1039\/D5SC00452G"},{"key":"ref5\/cit5a","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4039(00)61389-8"},{"key":"ref5\/cit5b","doi-asserted-by":"publisher","DOI":"10.1021\/jo00086a009"},{"key":"ref5\/cit5c","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2022.114579"},{"key":"ref5\/cit5d","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2006.01.148"},{"key":"ref5\/cit5e","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1260163"},{"key":"ref6\/cit6a","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.5b00060"},{"key":"ref6\/cit6b","doi-asserted-by":"publisher","DOI":"10.1002\/asia.201800537"},{"key":"ref6\/cit6c","doi-asserted-by":"publisher","DOI":"10.1002\/ajoc.201700538"},{"key":"ref6\/cit6d","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1612305"},{"key":"ref6\/cit6e","doi-asserted-by":"publisher","DOI":"10.1002\/cjoc.202000107"},{"key":"ref6\/cit6f","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.9b00635"},{"key":"ref6\/cit6g","doi-asserted-by":"publisher","DOI":"10.1038\/s41570-021-00321-1"},{"key":"ref6\/cit6h","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2021.132456"},{"key":"ref6\/cit6i","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202108630"},{"key":"ref6\/cit6j","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.1c03459"},{"key":"ref6\/cit6k","doi-asserted-by":"publisher","DOI":"10.1007\/s11426-022-1291-2"},{"key":"ref6\/cit6l","doi-asserted-by":"publisher","DOI":"10.1038\/s41929-024-01235-z"},{"key":"ref6\/cit6m","doi-asserted-by":"crossref","first-page":"111052","DOI":"10.1016\/j.cclet.2025.111052","volume":"36","author":"Bingbing D.","year":"2025","journal-title":"Chin. Chem. Lett."},{"key":"ref6\/cit6n","doi-asserted-by":"publisher","DOI":"10.1039\/D4CS01179A"},{"key":"ref6\/cit6o","doi-asserted-by":"publisher","DOI":"10.1039\/D5CS00600G"},{"key":"ref6\/cit6p","doi-asserted-by":"publisher","DOI":"10.1039\/D1QO01127H"},{"key":"ref7\/cit7a","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.6b03663"},{"key":"ref7\/cit7b","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.8b00550"},{"key":"ref8\/cit8a","doi-asserted-by":"publisher","DOI":"10.1021\/ol202272t"},{"key":"ref8\/cit8b","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201204145"},{"key":"ref8\/cit8c","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201303247"},{"key":"ref8\/cit8d","doi-asserted-by":"publisher","DOI":"10.1039\/C5OB00176E"},{"key":"ref8\/cit8e","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.7b00820"},{"key":"ref8\/cit8f","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.0c01112"},{"key":"ref8\/cit8g","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.2c02185"},{"key":"ref8\/cit8h","doi-asserted-by":"publisher","DOI":"10.1039\/D2QO01736A"},{"key":"ref8\/cit8i","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.3c00793"},{"key":"ref8\/cit8j","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.2c03945"},{"key":"ref8\/cit8k","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.2c00952"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/acs.joc.0c00657"}],"container-title":["The Journal of Organic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.joc.6c00614","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.joc.6c00614","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T08:12:17Z","timestamp":1778832737000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.joc.6c00614"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,4]]},"references-count":39,"alternative-id":["10.1021\/acs.joc.6c00614"],"URL":"https:\/\/doi.org\/10.1021\/acs.joc.6c00614","relation":{},"ISSN":["0022-3263","1520-6904"],"issn-type":[{"value":"0022-3263","type":"print"},{"value":"1520-6904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,4]]},"article-number":"acs.joc.6c00614"}}