{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T17:09:24Z","timestamp":1789751364733,"version":"4.0.1"},"reference-count":64,"publisher":"American Chemical Society (ACS)","issue":"37","license":[{"start":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100004260","name":"Renmin University of China","doi-asserted-by":"publisher","award":["RUC25QSDL134"],"award-info":[{"award-number":["RUC25QSDL134"]}],"id":[{"id":"10.13039\/501100004260","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005089","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["2252010"],"award-info":[{"award-number":["2252010"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22571319"],"award-info":[{"award-number":["22571319"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We report an operationally simple synthesis of \u03b3-pyrones via the defluorinative annulation of \u03b1-trifluoromethyl ketones with 1,3-dicarbonyl compounds. 18O-labeling experiments revealed that an intramolecular 1,3-oxygen transposition occurs within the \u03b1-trifluoromethyl ketone moiety during the transformation. Downstream transformations have also been demonstrated to showcase the utility of this protocol.<\/jats:p>","DOI":"10.1021\/acs.joc.6c01099","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T16:10:17Z","timestamp":1788451817000},"page":"12568-12577","source":"Crossref","is-referenced-by-count":0,"title":["Synthesis of \u03b3-Pyrones\nfrom \u03b1-Trifluoromethyl\nKetones and 1,3-Dicarbonyls via Defluorinative Annulation\/1,3-Oxygen\nTransposition"],"prefix":"10.1021","volume":"91","author":[{"given":"Yahui","family":"Ma","sequence":"first","affiliation":[{"name":"Renmin University of China , , ,","place":["Beijing, China, 100872"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyu","family":"Yin","sequence":"additional","affiliation":[{"name":"Renmin University of China , , ,","place":["Beijing, China, 100872"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanjin","family":"Chen","sequence":"additional","affiliation":[{"name":"Yunnan Minzu University , , ,","place":["Kunming, China, 650504"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5361-6659","authenticated-orcid":true,"given":"Dawei","family":"Gong","sequence":"additional","affiliation":[{"name":"Jilin Normal University , , ,","place":["Changchun, China, 130103"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2850-8952","authenticated-orcid":true,"given":"Leiyang","family":"Lv","sequence":"additional","affiliation":[{"name":"Renmin University of China , , ,","place":["Beijing, China, 100872"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,9,2]]},"reference":[{"key":"2026091808080728900_cit1","doi-asserted-by":"publisher","first-page":"4151","DOI":"10.1039\/D5QO00163C","article-title":"Recent Developments in Organic Synthesis\nfor Constructing Carbon Frameworks Using Transposition Strategies","volume":"12","author":"Gat","year":"2025","journal-title":"Org. Chem. Front."},{"key":"2026091808080728900_cit2a","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1002\/anie.199709761","article-title":"Mechanistic Insights into the Very Efficient [ReO3OSiR3]-Catalyzed Isomerization of Allyl Alcohols","volume":"36","author":"Bellemin-Laponnaz","year":"1997","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026091808080728900_cit2b","doi-asserted-by":"publisher","first-page":"4381","DOI":"10.1039\/c4cs00036f","article-title":"Recent Developments of Direct Rhenium-Catalyzed [1,3]-Transpositions\nof Allylic Alcohols and Their Silyl Ethers","volume":"43","author":"Volchkov","year":"2014","journal-title":"Chem. Soc. Rev."},{"key":"2026091808080728900_cit3a","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1021\/cr60273a001","article-title":"Rupe and Meyer-Schuster rearrangements","volume":"71","author":"Swaminathan","year":"1971","journal-title":"Chem. Rev."},{"key":"2026091808080728900_cit3b","doi-asserted-by":"publisher","first-page":"4149","DOI":"10.1039\/b912099h","article-title":"The Meyer\u2013Schuster Rearrangement\nfor the Synthesis of \u03b1,\u03b2-Unsaturated\nCarbonyl Compounds","volume":"7","author":"Engel","year":"2009","journal-title":"Org. Biomol. Chem."},{"key":"2026091808080728900_cit3c","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1002\/ejoc.202001494","article-title":"Recent Developments\nin the Meyer-Schuster Rearrangement","volume":"2021","author":"Justaud","year":"2021","journal-title":"Eur. J.\nOrg. Chem."},{"key":"2026091808080728900_cit4a","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1038\/nchem.2445","article-title":"Remote Functionalization\nthrough Alkene Isomerization","volume":"8","author":"Vasseur","year":"2016","journal-title":"Nat. Chem."},{"key":"2026091808080728900_cit4b","doi-asserted-by":"publisher","first-page":"13654","DOI":"10.1002\/anie.201906124","article-title":"Positional and Geometrical\nIsomerisation of Alkenes: The Pinnacle of Atom Economy","volume":"58","author":"Molloy","year":"2019","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026091808080728900_cit5a","doi-asserted-by":"publisher","DOI":"10.1002\/tcr.202200221","article-title":"Merging Fluorine Incorporation\nand Functional Group Migration","volume":"23","author":"Ma","year":"2023","journal-title":"Chem. Rec."},{"key":"2026091808080728900_cit5b","doi-asserted-by":"publisher","first-page":"1705","DOI":"10.1039\/D3QO00049D","article-title":"Ruthenium-Catalyzed 1,3-Indolyl Migration\nwithin \u03b1,\u03b1-Disubstituted Allylic Alcohols","volume":"10","author":"Zhang","year":"2023","journal-title":"Org. Chem. Front."},{"key":"2026091808080728900_cit6","doi-asserted-by":"publisher","first-page":"3418","DOI":"10.1039\/b710379d","article-title":"Advances in the Metallotropic [1,3]-Shift of Alkynyl Carbenoids","volume":"5","author":"Lee","year":"2007","journal-title":"Org. Biomol. Chem."},{"key":"2026091808080728900_cit7a","doi-asserted-by":"publisher","first-page":"9882","DOI":"10.1021\/ja504892c","article-title":"Gold-Catalyzed\n1,3-Transposition of Ynones","volume":"136","author":"Shiroodi","year":"2014","journal-title":"J. Am. Chem. Soc."},{"issue":"2","key":"2026091808080728900_cit7b","doi-asserted-by":"publisher","first-page":"960","DOI":"10.1021\/acscatal.7b04262","article-title":"Gold(I)-Catalyzed 1,3-O-Transposition\nof Ynones: Mechanism and Catalytic Acceleration with Electron-Rich\nAldehydes","volume":"8","author":"Aikonen","year":"2018","journal-title":"ACS Catal."},{"key":"2026091808080728900_cit7c","doi-asserted-by":"publisher","first-page":"1167","DOI":"10.1039\/D4QO01890G","article-title":"Tf2O-Induced Selective 1,3-Transposition\/Cyclization of Ynones in DMF","volume":"12","author":"Lan","year":"2025","journal-title":"Org. Chem. Front."},{"key":"2026091808080728900_cit8","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1126\/science.abl7854","article-title":"Carbonyl 1,2-Transposition through\nTriflate-Mediated \u03b1-Amination","volume":"374","author":"Wu","year":"2021","journal-title":"Science"},{"key":"2026091808080728900_cit9a","doi-asserted-by":"publisher","first-page":"9747","DOI":"10.1002\/anie.201303576","article-title":"Oxidative Trifluoromethylation of\nUnactivated Olefins: An Efficient and Practical Synthesis of \u03b1-Trifluoromethyl-Substituted Ketones","volume":"52","author":"Deb","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026091808080728900_cit9b","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.1021\/acs.joc.0c02431","article-title":"Scissoring Enaminone C\u2550C Double\nBond by Free Radical Process for the Synthesis of \u03b1-Trifluoromethyl Ketones with CF3SO2Na","volume":"86","author":"Gan","year":"2021","journal-title":"J. Org. Chem."},{"key":"2026091808080728900_cit9c","doi-asserted-by":"publisher","first-page":"3741","DOI":"10.1039\/D3QO00609C","article-title":"Dual Role of BrCF2CO2Et: Difluorocarbene-Enabled\nAccess to \u03b1-Trifluoromethyl Ketones from Sulfoxonium\nYlides","volume":"10","author":"Wu","year":"2023","journal-title":"Org. Chem. Front."},{"key":"2026091808080728900_cit10a","doi-asserted-by":"publisher","first-page":"4406","DOI":"10.1039\/C8CC01568F","article-title":"Pd-Catalyzed\nDefluorination\/Arylation of \u03b1-Trifluoromethyl Ketones via Consecutive \u03b2-F Elimination and C\u2013F Bond Activation","volume":"54","author":"Xu","year":"2018","journal-title":"Chem. Commun."},{"key":"2026091808080728900_cit10b","doi-asserted-by":"publisher","first-page":"2223","DOI":"10.1021\/acs.orglett.9b00518","article-title":"Direct Access\nto \u03b1-Oxoketene Aminals via Copper-Catalyzed\nFormal Oxyaminalization of Alkenes under Mild Conditions","volume":"21","author":"Wang","year":"2019","journal-title":"Org. Lett."},{"issue":"86","key":"2026091808080728900_cit10c","doi-asserted-by":"publisher","first-page":"17197","DOI":"10.1021\/acs.joc.1c02288","article-title":"Three-Component\nReactions of \u03b1-CF3 Carbonyls, NaN3, and Amines for the Synthesis of NH-1,2,3-Triazoles","volume":"86","author":"Lv","year":"2021","journal-title":"J. Org. Chem."},{"key":"2026091808080728900_cit10d","doi-asserted-by":"publisher","first-page":"2013","DOI":"10.1039\/D1QO01749G","article-title":"Multiple-Fold C\u2013F Bond Functionalization\nfor the Synthesis of (Hetero)Cyclic Compounds: Fluorine as a Detachable\nChemical Handle","volume":"9","author":"Ge","year":"2022","journal-title":"Org. Chem. Front."},{"key":"2026091808080728900_cit10e","doi-asserted-by":"publisher","first-page":"10137","DOI":"10.1021\/acs.joc.3c00979","article-title":"Amine-Induced Selective\nC\u2013C Bond Cleavage of 2,2,2-Trifluoroethyl Carbonyls for the\nSynthesis of Ureas and Amides","volume":"88","author":"Mao","year":"2023","journal-title":"J. Org. Chem."},{"key":"2026091808080728900_cit10f","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aea4120","article-title":"\u03b2-Acyloxyl Alkenyl Amide Synthesis via Multiple Defluorination: \u03b1-Trifluoromethyl Ketone\u2013Amine as Synergystic\nPeptide Coupling Reagent","volume":"11","author":"Cao","year":"2025","journal-title":"Sci. Adv."},{"key":"2026091808080728900_cit11","doi-asserted-by":"publisher","first-page":"86","DOI":"10.6023\/cjoc202411018","article-title":"Advances in\nthe Synthesis of \u03b1-Trifluoromethyl Ketones\nand Their Application via Defluorinative Reactions","volume":"45","author":"Cao","year":"2025","journal-title":"Chin. J. Org. Chem."},{"key":"2026091808080728900_cit12","doi-asserted-by":"publisher","first-page":"1402","DOI":"10.1002\/adsc.202200094","article-title":"Three-Component Coupling\nof \u03b1-Trifluoromethyl Carbonyls, Azides and\nAmines for the Regioselective Synthesis of 1,4,5-Trisubstituted 1,2,3-Triazoles","volume":"364","author":"Gao","year":"2022","journal-title":"Adv. Synth. Catal."},{"key":"2026091808080728900_cit13a","doi-asserted-by":"publisher","first-page":"1959","DOI":"10.1021\/np200454z","article-title":"Reappraising\nthe Structures and Distribution of Metabolites\nfrom Black Aspergilli Containing Uncommon 2-Benzyl-4H-Pyran-4-One and 2-Benzylpyridin-4(1H)-One Systems","volume":"74","author":"Henrikson","year":"2011","journal-title":"J. Nat. Prod."},{"key":"2026091808080728900_cit13b","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1007\/s00044-010-9534-8","article-title":"Synthesis and Calcium Channel Antagonist Activity of\nNovel 1,4-Dihydropyridine Derivatives Possessing 4-Pyrone Moieties","volume":"21","author":"Shahrisa","year":"2012","journal-title":"Med. Chem. Res."},{"key":"2026091808080728900_cit13c","doi-asserted-by":"publisher","first-page":"4960","DOI":"10.1021\/cr400265z","article-title":"Chromone: A Valid Scaffold in Medicinal Chemistry","volume":"114","author":"Gaspar","year":"2014","journal-title":"Chem. Rev."},{"key":"2026091808080728900_cit14","doi-asserted-by":"publisher","first-page":"6073","DOI":"10.1039\/c2cc31581e","article-title":"Dicyanomethylene-4H-Pyran Chromophores\nfor OLED Emitters, Logic Gates and Optical Chemosensors","volume":"48","author":"Guo","year":"2012","journal-title":"Chem. Commun."},{"issue":"25","key":"2026091808080728900_cit15a","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1021\/jo01074a013","article-title":"Aroylations of \u03b2-Diketones at the Terminal Methyl Group to Form 1,3,5-Triketones.\nCyclizations to 4-Pyrones and 4-Pyridones","volume":"25","author":"Light","year":"1960","journal-title":"J.\nOrg. Chem."},{"issue":"10","key":"2026091808080728900_cit15b","doi-asserted-by":"publisher","first-page":"2569","DOI":"10.1021\/ol800860p","article-title":"Rate-Accelerating Effect\nby the Neighboring-Group Participation of Protecting Groups in the\nDehydrative Cyclization of 1,3,5-Triketones","volume":"10","author":"Sakakura","year":"2008","journal-title":"Org. Lett."},{"key":"2026091808080728900_cit15c","doi-asserted-by":"publisher","first-page":"5002","DOI":"10.1021\/jo900702u","article-title":"Synthesis of Trifluoromethyl-Substituted Arenes, Cyclohexenones\nand Pyran-4-Ones by Cyclocondensation of 1,3-Bis(Silyloxy)-1,3-Butadienes\nwith 4,4-Dimethoxy-1,1,1-Trifluorobut-3-En-2-One: Influence of the\nLewis Acid on the Product Distribution","volume":"74","author":"Bunescu","year":"2009","journal-title":"J. Org.\nChem."},{"key":"2026091808080728900_cit16","doi-asserted-by":"publisher","first-page":"15051","DOI":"10.1021\/acs.joc.0c01924","article-title":"\u201cOne-Pot\u201d\nSynthesis of \u03b3-Pyrones from Aromatic Ketones\/Heteroarenes\nand Carboxylic Acids","volume":"85","author":"Sun","year":"2020","journal-title":"J. Org. Chem."},{"key":"2026091808080728900_cit17","doi-asserted-by":"publisher","first-page":"3882","DOI":"10.1021\/acs.orglett.6b01891","article-title":"Alkynyl Acylammoniums\nas Electrophilic 3C Synthons in a Formal [3 + 3] Annulation: Access\nto Functionalized 4H-Pyran-4-Ones","volume":"18","author":"Dong","year":"2016","journal-title":"Org. Lett."},{"key":"2026091808080728900_cit18","doi-asserted-by":"publisher","first-page":"9603","DOI":"10.1021\/acs.joc.9b01254","article-title":"Synthesis of \u03b3-Pyrones from Formal [4 + 2]\nCyclization of Ketene\nDithioacetals with Acyl Chlorides","volume":"84","author":"Wang","year":"2019","journal-title":"J. Org. Chem."},{"key":"2026091808080728900_cit19a","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1021\/acs.orglett.8b03989","article-title":"Gold(I)-Catalyzed\nHydroxy Group Assisted C(Sp2)\u2013H Alkylation of Enaminones\nwith Diazo Compounds To Access 3-Alkyl Chromones","volume":"21","author":"Bagle","year":"2019","journal-title":"Org. Lett."},{"key":"2026091808080728900_cit19b","doi-asserted-by":"publisher","first-page":"7138","DOI":"10.1021\/acs.joc.9b00814","article-title":"One-Pot\nSynthesis of B-Ring Ortho-Hydroxylated Sappanin-Type Homoisoflavonoids","volume":"84","author":"Mrug","year":"2019","journal-title":"J. Org. Chem."},{"key":"2026091808080728900_cit19c","doi-asserted-by":"publisher","first-page":"4896","DOI":"10.1021\/acs.joc.0c02294","article-title":"Arylation of Ortho-Hydroxyarylenaminones\nby Sulfonium Salts and Arenesulfonyl Chlorides: An Access to Isoflavones","volume":"86","author":"Mkrtchyan","year":"2021","journal-title":"J. Org. Chem."},{"key":"2026091808080728900_cit19d","doi-asserted-by":"publisher","first-page":"12378","DOI":"10.1021\/acs.joc.1c01347","article-title":"Electrochemical\nC-H Halogenations of Enaminones and Electron-Rich Arenes with Sodium\nHalide (NaX) as Halogen Source for the Synthesis of 3-Halochromones\nand Haloarenes","volume":"86","author":"Lin","year":"2021","journal-title":"J. Org. Chem."},{"key":"2026091808080728900_cit19e","doi-asserted-by":"publisher","first-page":"3003","DOI":"10.1021\/acs.orglett.2c00912","article-title":"Rh-Catalyzed [4 + 2] Annulation with a Removable Monodentate\nStructure toward Iminopyranes and Pyranones by C\u2013H Annulation","volume":"24","author":"Fu","year":"2022","journal-title":"Org. Lett."},{"key":"2026091808080728900_cit19f","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1021\/acs.joc.3c02399","article-title":"Photoredox-Catalyzed\nTandem Cyclization of Enaminones with N-Sulfonylaminopyridinium\nSalts toward the Synthesis of 3-Sulfonaminated Chromones","volume":"89","author":"Hu","year":"2024","journal-title":"J. Org. Chem."},{"key":"2026091808080728900_cit19g","doi-asserted-by":"publisher","first-page":"12024","DOI":"10.1021\/acs.orglett.5c03726","article-title":"A Cut-and-Sew\nStrategy with Rongalite: Sulfonylmethylation Relay of Two Distinct\nAlkenes to Access Lactam\u2013Chromone Hybrid Alkyl\u2013Alkyl\nSulfones","volume":"27","author":"Wang","year":"2025","journal-title":"Org. Lett."},{"key":"2026091808080728900_cit19h","doi-asserted-by":"publisher","first-page":"6031","DOI":"10.1021\/acs.joc.5c00424","article-title":"Visible-Light-Driven\nTandem Cyclization of o-Hydroxyaryl Enaminones: Access\nto 3-(\u03b1-Arylsulfonamido)Trifluoroethyl Chromones","volume":"90","author":"Yuan","year":"2025","journal-title":"J. Org. Chem."},{"key":"2026091808080728900_cit19i","doi-asserted-by":"publisher","first-page":"112202","DOI":"10.1016\/j.cclet.2025.112202","article-title":"Photocatalytic Free\nRadical Geminal Carboamination of \u03b1-Diazo Esters\ntoward Chromone-Derived \u03b1-Amino Acids","volume":"37","author":"Liu","year":"2026","journal-title":"Chin. Chem. Lett."},{"key":"2026091808080728900_cit20a","doi-asserted-by":"publisher","first-page":"12018","DOI":"10.1021\/jo402055a","article-title":"Br\u00f8nsted\nAcid Catalyzed and NIS-Promoted Cyclization\nof Diynones: Selective Synthesis of 4-Pyrone, 4-Pyridone, and 3-Pyrrolone\nDerivatives","volume":"78","author":"Qiu","year":"2013","journal-title":"J. Org. Chem."},{"key":"2026091808080728900_cit20b","doi-asserted-by":"publisher","first-page":"7681","DOI":"10.1021\/acs.orglett.0c02892","article-title":"Regiodivergent Hydration\u2013Cyclization of Diynones under Gold\nCatalysis","volume":"22","author":"Solas","year":"2020","journal-title":"Org. Lett."},{"key":"2026091808080728900_cit20c","doi-asserted-by":"publisher","first-page":"14476","DOI":"10.1021\/acs.joc.1c01340","article-title":"Phosphine-Catalyzed Synthesis of\n3-Allyl-4-Pyrones by the Tandem Reaction of Diynones and Allylic Alcohols","volume":"86","author":"Ye","year":"2021","journal-title":"J. Org. Chem."},{"key":"2026091808080728900_cit20d","doi-asserted-by":"publisher","first-page":"7216","DOI":"10.1021\/acs.orglett.2c03017","article-title":"Synthesis of 3-SCF2H-\/3-SCF3-Chromones via Interrupted Pummerer Reaction\/Intramolecular\nCyclization Mediated by Difluoromethyl or Trifluoromethyl Sulfoxide\nand Tf2O","volume":"24","author":"Li","year":"2022","journal-title":"Org. Lett."},{"key":"2026091808080728900_cit20e","doi-asserted-by":"publisher","first-page":"7042","DOI":"10.1021\/acs.orglett.2c02914","article-title":"Synthesis of 4-Pyrones by Formal\nHydration of 1,3-Diynones Promoted by 1,4-Addition of Piperidine","volume":"24","author":"Perera","year":"2022","journal-title":"Org. Lett."},{"key":"2026091808080728900_cit20f","doi-asserted-by":"publisher","first-page":"4496","DOI":"10.1021\/acs.joc.3c02711","article-title":"Cyclization Reactions of In Situ-Generated Acyl Ketene with Ynones\nto Form Oxacycles","volume":"89","author":"Perera","year":"2024","journal-title":"J. Org. Chem."},{"key":"2026091808080728900_cit20g","doi-asserted-by":"publisher","first-page":"1568","DOI":"10.1021\/acs.orglett.5c00214","article-title":"Sulfinate-Promoted Defluorinative\nCyclization of Polyfluoroalkyl Tetralones Enabled by Photocatalysis","volume":"27","author":"Tang","year":"2025","journal-title":"Org. Lett."},{"key":"2026091808080728900_cit21a","doi-asserted-by":"publisher","first-page":"2566","DOI":"10.1002\/adsc.201301086","article-title":"One-Pot\nSynthesis of Multi-Substituted 4-Pyrones by a Gold- Catalyzed Cascade\nof Wolff Rearrangement\/[4 + 2] Cycloaddition\/Elimination Reactions","volume":"356","author":"Neupane","year":"2014","journal-title":"Adv. Synth. Catal."},{"key":"2026091808080728900_cit21b","doi-asserted-by":"publisher","first-page":"4523","DOI":"10.1002\/adsc.201800874","article-title":"Transition-Metal-Free Regioselective\nConstruction of Diverse 3-Carbonyl Functionalized 4-Pyrones via Thermal\nWolff-Rearrangement of Diazodicarbonyls","volume":"360","author":"Park","year":"2018","journal-title":"Adv.\nSynth. Catal."},{"key":"2026091808080728900_cit21c","doi-asserted-by":"publisher","first-page":"3447","DOI":"10.1039\/C8QO01006D","article-title":"Regiospecific Construction\nof Diverse and Polyfunctionalized \u03b3-Pyrone\nCores by Indium(III)-Catalyzed Annulation of Diazodicarbonyls with\nActive Methylenes, 4-Hydroxycoumarins, or 4-Hydroxyquinolinone","volume":"5","author":"Maezono","year":"2018","journal-title":"Org. Chem. Front."},{"key":"2026091808080728900_cit21d","doi-asserted-by":"publisher","first-page":"6207","DOI":"10.1021\/acs.joc.9b00418","article-title":"On-Water\nCp*Ir(III)-Catalyzed C\u2013H Functionalization for the Synthesis\nof Chromones through Annulation of Salicylaldehydes with Diazo-Ketones","volume":"84","author":"Debbarma","year":"2019","journal-title":"J. Org. Chem."},{"key":"2026091808080728900_cit21e","doi-asserted-by":"publisher","first-page":"9227","DOI":"10.1021\/acs.orglett.4c03329","article-title":"Synergistic Rh(II)- and Zn(II)-Catalyzed\n[3 + 3] Annulation of Diazoenals and \u03b1-Hydroxy\nKetones for the Direct Synthesis of 2H-Pyrans, A\nGateway Toward \u03b3-Pyrones","volume":"26","author":"Mandal","year":"2024","journal-title":"Org. Lett."},{"key":"2026091808080728900_cit59"},{"key":"2026091808080728900_cit23","doi-asserted-by":"publisher","first-page":"11590","DOI":"10.1021\/acs.joc.3c00907","article-title":"Oxidative Ring-Opening Transformation of 5-Acyl-4-Pyrones\nas an Approach for the Tunable Synthesis of Hydroxylated Pyrones and\nFurans","volume":"88","author":"Steparuk","year":"2023","journal-title":"J. Org. Chem."},{"key":"2026091808080728900_cit61","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1002\/352760393X","volume-title":"Modern Fluoroorganic\nChemistry: Synthesis, Reactivity, Applications","author":"Kirsch","year":"2004"},{"key":"2026091808080728900_cit25a","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1021\/acs.orglett.4c04488","article-title":"Modular Synthesis of Furans with\nFour Nonidentical Substituents by Aqueous Defluorinative Reaction\nof Trifluoromethyl Enones with Two Nucleophiles","volume":"27","author":"Huang","year":"2025","journal-title":"Org. Lett."},{"key":"2026091808080728900_cit25b","doi-asserted-by":"publisher","first-page":"5144","DOI":"10.1039\/D4QO00962B","article-title":"Multi-Functionalization of \u03b2-Trifluoromethyl\nEnones Enabled 2,3-Dihydrofuran Synthesis","volume":"11","author":"Hu","year":"2024","journal-title":"Org.\nChem. Front."},{"key":"2026091808080728900_cit25c","doi-asserted-by":"publisher","first-page":"16749","DOI":"10.1021\/acs.joc.5c01993","article-title":"Defluorinative Hydrophosphorylation\nof Trifluoromethylated Enones: Insight into the Roles of H-Phosphine\nOxide","volume":"90","author":"Ren","year":"2025","journal-title":"J. Org. Chem."},{"key":"2026091808080728900_cit26","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/j.jfluchem.2014.01.020","article-title":"Highly Efficient Cu(I)-Catalyzed\nTrifluoromethylation of Aryl(Heteroaryl) Enol Acetates with CF3 Radicals Derived from CF3SO2Na and\nTBHP at Room Temperature","volume":"161","author":"Lu","year":"2014","journal-title":"J. Fluorine Chem."}],"container-title":["The Journal of Organic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.joc.6c01099","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/joceah\/article-pdf\/91\/37\/12568\/68187074\/acs.joc.6c01099.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/joceah\/article-pdf\/91\/37\/12568\/68187074\/acs.joc.6c01099.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T16:23:29Z","timestamp":1789748609000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/joceah\/article\/91\/37\/12568\/5404585\/Synthesis-of-Pyrones-from-Trifluoromethyl-Ketones"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,2]]},"references-count":64,"journal-issue":{"issue":"37","published-online":{"date-parts":[[2026,9,2]]},"published-print":{"date-parts":[[2026,9,18]]}},"URL":"https:\/\/doi.org\/10.1021\/acs.joc.6c01099","relation":{},"ISSN":["0022-3263","1520-6904"],"issn-type":[{"value":"0022-3263","type":"print"},{"value":"1520-6904","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,2]]}}}