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This operationally simple and air-tolerant protocol provides rapid access to alkynyl sulfides and selenides in good to excellent yields within 1 h. By simply tuning the thiol\/KOH stoichiometry and reaction time, the reaction selectively affords alkynyl sulfides or symmetrical and unsymmetrical (Z)-1,2-dithioalkenes with exclusive Z-selectivity. The methodology features a broad substrate scope (&amp;gt;70 examples) and excellent functional-group tolerance. Control experiments, including D2O-labeling studies, support an ionic addition\u2013elimination pathway involving a vinyl anion intermediate. The present protocol offers an efficient, practical, and scalable approach for the synthesis of structurally diverse organosulfur and organoselenium compounds.<\/jats:p>","DOI":"10.1021\/acs.joc.6c01177","type":"journal-article","created":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T05:06:03Z","timestamp":1787375163000},"page":"11992-12009","source":"Crossref","is-referenced-by-count":0,"title":["Selective Mono-\nand Bis-Sulfenylation and Mono-Selenylation of 1-Bromoalkynes\nwith Thiols and Phenylselenol: Divergent Access to Alkynyl Sulfides\/Selenides\nand Symmetrical or Unsymmetrical (\n                    <i>Z<\/i>\n                    )-1,2-Dithioalkenes"],"prefix":"10.1021","volume":"91","author":[{"given":"Rekha","family":"Bai","sequence":"first","affiliation":[{"name":"National Chung Hsing University , , ,","place":["Taichung City, Taiwan, R.O.C., 40227"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Tung","family":"Chen","sequence":"additional","affiliation":[{"name":"National Chung Hsing University , , ,","place":["Taichung City, Taiwan, R.O.C., 40227"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chin-Fa","family":"Lee","sequence":"additional","affiliation":[{"name":"National Chung Hsing University , , ,","place":["Taichung City, Taiwan, R.O.C., 40227"]},{"name":"National Chung Hsing University , , ,","place":["Taichung City, Taiwan, R.O.C., 40227"]},{"name":"National Chung Hsing University , , ,","place":["Taichung City, Taiwan, R.O.C., 40227"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,8,21]]},"reference":[{"key":"2026090408095153100_cit1a","doi-asserted-by":"publisher","first-page":"23704","DOI":"10.1039\/D5RA03124A","article-title":"Frontiers\nin Bond Construction: Innovative\nApproaches to C-C and Carbon\u2013Heteroatom (C-S, C-N, C-O, C-Se,\nC-P) Transformations-A Review","volume":"15","author":"Islam","year":"2025","journal-title":"RSC Adv."},{"key":"2026090408095153100_cit1b","doi-asserted-by":"publisher","DOI":"10.1016\/j.apcata.2025.120714","article-title":"Sustainable Catalytic Strategies\nfor Carbon\u2013Carbon and Carbon-Heteroatom (C-S, C-N, C-O, C-Se)\nBond Formation: Green Pathways to Advanced Molecules","volume":"711","author":"Bhat","year":"2026","journal-title":"Appl. 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