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This transition-metal-free reaction proceeds rapidly at room temperature, featuring operational simplicity and scalability to gram quantities. Moreover, HFIP was recycled for further use by distillation, which makes this protocol a greener and more sustainable choice.<\/jats:p>","DOI":"10.1021\/acs.joc.6c01262","type":"journal-article","created":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T02:01:49Z","timestamp":1792720909000},"source":"Crossref","is-referenced-by-count":0,"title":["HFIP-Promoted Bis-Phosphorylation via Dual C\u2013P Coupling of Unprotected\n                    <i>sec<\/i>\n                    -Propargylic Alcohols and Phosphites: Access to Substituted (Prop-2-ene-1,2-diyl)(\n                    <i>E<\/i>\n                    )-Bisphosphonates"],"prefix":"10.1021","author":[{"given":"Showkat Ahmad","family":"Bhat","sequence":"first","affiliation":[{"name":"Ningbo University , , , ,","place":["Ningbo, Zhejiang, China, 315211"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Ningbo University , , , ,","place":["Ningbo, Zhejiang, China, 315211"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Peng","sequence":"additional","affiliation":[{"name":"Ningbo University , , , ,","place":["Ningbo, Zhejiang, China, 315211"]},{"name":"Ningbo University , , , ,","place":["Ningbo, Zhejiang, China, 315211"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3560-435X","authenticated-orcid":true,"given":"Yufen","family":"Zhao","sequence":"additional","affiliation":[{"name":"Ningbo University , , , ,","place":["Ningbo, Zhejiang, China, 315211"]},{"name":"Xiamen University , , ,","place":["Xiamen, China, 361005"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongbin","family":"Zhai","sequence":"additional","affiliation":[{"name":"Ningbo University , , , ,","place":["Ningbo, Zhejiang, China, 315211"]},{"name":"Shenzhen Graduate School of Peking University , , ,","place":["Shenzhen, China, 518055"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1169-6149","authenticated-orcid":true,"given":"Hua","family":"Zhao","sequence":"additional","affiliation":[{"name":"Ningbo University , , , ,","place":["Ningbo, Zhejiang, China, 315211"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,10,23]]},"reference":[{"key":"2026102222014375900_cit1a","doi-asserted-by":"publisher","first-page":"4862","DOI":"10.1021\/jm100213c","article-title":"Mercaptophosphonate Compounds as Broad-Spectrum Inhibitors of the Metallo-\u03b2-lactamases","volume":"53","author":"Lassaux","year":"2010","journal-title":"J. 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