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Though ene-azide cycloaddition emerged as a reliable strategy for their synthesis, it often requires metal catalysts and\/or high temperature. To tackle this challenge, we herein disclose our approach of visible-light photoredox catalysis (VLPC) by employing Rose Bengal (RB) as a organo-photocatalyst. The chemistry works under blue light-emitting diode illumination by generating a solvent radical intermediate through the cooperation of RB and DMF. The reaction works well for various organic azides and Michael acceptors generating a library of substituted triazoles (50 examples) in excellent regio- and product control. The scope of the methodology is highlighted through the formal synthesis of rufinamide, an antiepileptic drug. From a technoeconomic perspective, our procedure holds sustainable advantages like room temperature, an ambient atmosphere, no byproducts, good to excellent yields, extension to gram-scale synthesis, and a safe and inexpensive catalyst.<\/jats:p>","DOI":"10.1021\/acs.joc.6c01500","type":"journal-article","created":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T09:02:03Z","timestamp":1791968523000},"page":"14121-14130","source":"Crossref","is-referenced-by-count":0,"title":["Visible-Light Photoredox Catalysis Enabled Triazole Annulation of Azidophilic Michael Acceptors"],"prefix":"10.1021","volume":"91","author":[{"given":"Chandran","family":"Balamurugan","sequence":"first","affiliation":[{"name":"B. S. Abdur Rahman Crescent Institute of Science and Technology , , Vandalur, - , ,","place":["Chennai, Tamil Nadu, India, 600048"]},{"name":"Syngene International Limited , , Biocon Park, Bommasandra IV Phase, Jigani Link Road , - , ,","place":["Bangalore, Karnataka, India, 560099"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0356-2511","authenticated-orcid":true,"given":"Nitin S.","family":"Dange","sequence":"additional","affiliation":[{"name":"Syngene International Limited , , Biocon Park, Bommasandra IV Phase, Jigani Link Road , - , ,","place":["Bangalore, Karnataka, India, 560099"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5348-8810","authenticated-orcid":true,"given":"Kesavan","family":"Karthikeyan","sequence":"additional","affiliation":[{"name":"B. S. 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